Cognitive Dysfunction in Schizophrenia, Affective Disorder and Organic Brain Disease

1981 ◽  
Vol 139 (3) ◽  
pp. 190-194 ◽  
Author(s):  
Richard Abrams ◽  
Joel Redfield ◽  
Michael Alan Taylor

SummaryWe used the Wechsler Adult Itelligence Scale (WAIS) to study a sample of patients with affective disorder (N = 52), schizophrenia (N = 17) and organic brain disease (N = 8). Schizophrenic patients had lower verbal, performance and full-scale IQs than patients with affective disorder, but were no different from those with organic brain disease. An individual WAIS subscale analysis showed that, compared with affectives, schizophrenics had relatively poorer performance on language than non-language tasks.These differences were independent of age, sex, handedness, educational level or drug administration and are consistent with a variety of studies demonstrating significant cerebral dysfunction in carefully diagnosed schizophrenic patients.

1972 ◽  
Vol 121 (562) ◽  
pp. 259-264 ◽  
Author(s):  
Randall Rosenthal ◽  
Llewellyn B. Bigelow

Despite extensive gross and microscopic scrutiny, no consistent pathological findings have emerged from studies of autopsy material from schizophrenic patients. Dunlap (1924) carried out the first controlled study involving schizophrenic and control brains and concluded that ‘there was not even a suspicion of consistent organic brain disease as a basis for the psychosis of schizophrenia’. More recently both Wolf and Cowen (1952), and Weinstein (1954), reviewed the neuropathological literature and concluded that there were no consistent findings at autopsy that could be construed as characteristic of schizophrenia. These authors felt that earlier claims were based on failure to appreciate the range of normal variation in the brain as well as a failure to include an adequate control population in the study.


1981 ◽  
Vol 14 (2) ◽  
pp. 105-111
Author(s):  
G. Ladurner ◽  
W. Pieringer ◽  
W.D. Sager

1983 ◽  
Vol 13 (2) ◽  
pp. 155-159 ◽  
Author(s):  
Robert W. Butler ◽  
William A. Dickinson ◽  
Charles Katholi ◽  
James H. Halsey

1997 ◽  
Vol 3 (4) ◽  
pp. 211-218 ◽  
Author(s):  
David Jolley ◽  
David Baxter

The purpose of this review is to outline current knowledge on the life expectation of people suffering from organic brain disease, the techniques available for describing and comparing life expectation in populations, factors which are associated with longer and shorter life expectation, and the causes of death among patients with this condition.


1978 ◽  
Vol 133 (1) ◽  
pp. 22-27 ◽  
Author(s):  
Aggrey W. Burke

SummaryDuring a six-month period, physical disorder was found among 50 per cent of the 133 patients at a day hospital. Few of these cases (5) had organic brain syndromes. Among the remainder (62) physical disorder was not associated with sex, formal psychiatric diagnosis or time of referral to the hospital; of those 33 patients with a neurological disorder, one-third had previously been diagnosed to be hysterical. For this ‘hysterical’ group, however, associations with folate deficiency, organic brain disease, and depression were noted. The need is demonstrated for routine investigations among day hospital patients with particular attention for those with atypical features.


Brain ◽  
2007 ◽  
Vol 130 (7) ◽  
pp. 1712-1714
Author(s):  
A. Compston

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