Antibody Levels to Herpes Simplex Type 1, Measles and Rubella Viruses in Psychiatric Patients

1974 ◽  
Vol 125 (588) ◽  
pp. 461-465 ◽  
Author(s):  
P. E. Halonen ◽  
R. Rimon ◽  
Katve Arohonka ◽  
V. Jäntti
Keyword(s):  
Herpes Simplex ◽  
Neurological Diseases ◽  
Psychiatric Patients ◽  
Subacute Sclerosing Panencephalitis ◽  
Systematic Search ◽  
Brain Cells ◽  
Histopathological Studies ◽  
Antibody Levels ◽  
Infectious Aetiology

The systematic search of aetiological agents from a variety of slowly progressing or subacute neurological diseases has revealed causative viruses or virus-like agents from kuru, Creutzfeldt-Jacob disease and other forms of presenile dementias, subacute sclerosing panencephalitis, progressive multifocal encephalopathy, and from many similar neurological diseases in animals (Gajdusek and Gibbs, 1973; Gajdusek, 1973). The first two diseases called subacute spongiform virus encephalopathies (Gajdusek and Gibbs, 1971) have many interesting features including heredo-familial occurrence and totally non-inflammatory neuropathology. Thus the epidemiology of these diseases is not typical for diseases with infectious aetiology, and the histopathological studies do not suggest the presence of extremely high-titred infectious material in brain cells.

The possible relationship of herpes simplex virus infection to cause of retardation in severe mental handicap

1980 ◽  
Vol 10 (3) ◽  
pp. 555-557
Author(s):  
A. H. Reid ◽  
K. W. Martin ◽  
B. R. Ballinger ◽  
B. B. Heather
Keyword(s):  
Mental Retardation ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Herpes Simplex Virus Infection ◽  
Research Findings ◽  
Simplex Virus ◽  
Antibody Levels ◽  
Relationship Of ◽  
The Relationship

SYNOPSISThe relationship between herpes simplex virus type 1 and mental retardation is explored by studying the antibody levels to this virus in a group of 86 severely and profoundly retarded adults. A tendency towards higher antibody levels is found in patients whose retardation is of unknown aetiology. The relationship of these observations to previous research findings and the possible significance of herpes simplex virus in the aetiology of mental retardation are discussed

Antibodies to Epstein-Barr virus, herpes simplex type 1, cytomegalovirus and measles virus in psychiatric patients

1981 ◽  
Vol 67 (4) ◽  
pp. 333-339 ◽  
Author(s):  
T. Gotlieb-Stematsky ◽  
J. Zonis ◽  
A. Arlazoroff ◽  
T. Mozes ◽  
M. Sigal ◽  
...  
Keyword(s):  
Herpes Simplex ◽  
Measles Virus ◽  
Epstein Barr Virus ◽  
Psychiatric Patients ◽  
Herpes Simplex Type ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals Herpes simplex virus Type 1 positivity in various neurological diseases

2019 ◽  
Vol 76 (1) ◽  
pp. 23-30
Author(s):  
Aylin Altay Koçak ◽  
Meryem Çolak ◽  
Ceyla İrkeç ◽  
Ayşe Serdaroğlu ◽  
Anıl Aktaş Tapısız ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Neurological Diseases ◽  
Simplex Virus

Presence of antibody in virus-infected brain cells of SSPE ferrets

1983 ◽  
Vol 41 ◽  
pp. 804-805
Author(s):  
Hannah R. Brown ◽  
Tammy L. Donato ◽  
Halldor Thormar
Keyword(s):  
Measles Virus ◽  
Plasma Cells ◽  
Subacute Sclerosing Panencephalitis ◽  
Protein A ◽  
Neutralizing Antibody ◽  
Brain Cells ◽  
Antibody Titers ◽  
A Cell ◽  
The Central Nervous System ◽  
The Brain

Measles virus specific immunoglobulin G (IgG) has been found in the brains of patients with subacute sclerosing panencephalitis (SSPE), a slowly progressing disease of the central nervous system (CNS) in children. IgG/albumin ratios indicate that the antibodies are synthesized within the CNS. Using the ferret as an animal model to study the disease, we have been attempting to localize the Ig's in the brains of animals inoculated with a cell associated strain of SSPE. In an earlier report, preliminary results using Protein A conjugated to horseradish peroxidase (PrAPx) (Dynatech Diagnostics Inc., South Windham, ME.) to detect antibodies revealed the presence of immunoglobulin mainly in antibody-producing plasma cells in inflammatory lesions and not in infected brain cells.In the present experiment we studied the brain of an SSPE ferret with neutralizing antibody titers of 1:1024 in serum and 1:512 in CSF at time of sacrifice 7 months after i.c. inoculation with SSPE measles virus-infected cells. The animal was perfused with saline and portions of the brain and spinal cord were immersed in periodate-lysine-paraformaldehyde (P-L-P) fixative. The ferret was not perfused with fixative because parts of the brain were used for virus isolation.

Role of herpes simplex virus type 1 (HSV-1) in the pathogenesis of peptic ulcer disease

2001 ◽  
Vol 120 (5) ◽  
pp. A136-A137
Author(s):  
K TSAMAKIDES ◽  
E PANOTOPOULOU ◽  
D DIMITROULOPOULOS ◽  
M CHRISTOPOULO ◽  
D XINOPOULOS ◽  
...  
Keyword(s):  
Peptic Ulcer ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Peptic Ulcer Disease ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Ulcer Disease ◽  
Simplex Virus
Sign in / Sign up

Export Citation Format

Share Document