Amitriptyline and Perphenazine in Depressive Illness a Controlled Trial

1967 ◽  
Vol 113 (495) ◽  
pp. 195-199 ◽  
Author(s):  
Ijaz Haider
Keyword(s):  
Controlled Trial ◽  
Depressive Illness ◽  
Double Blind Trial ◽  
Double Blind ◽  
Matching Placebo ◽  
Blind Trial ◽  
Amitriptyline Hydrochloride

This paper describes a “double-blind” trial comparing ‘Triptafen’ tablets—each containing amitriptyline hydrochloride 25 mg. and perphenazine 2 mg.—with a matching placebo in the treatment of depressive illness.

scholarly journals Can Homeopaths Detect Homeopathic Medicines by Dowsing? A Randomized, Double-Blind, Placebo-Controlled Trial

2002 ◽  
Vol 95 (4) ◽  
pp. 189-191 ◽  
Author(s):  
R McCarney ◽  
P Fisher ◽  
F Spink ◽  
G Flint ◽  
R van Haselen
Keyword(s):  
Problem Solving ◽  
Confidence Interval ◽  
Controlled Trial ◽  
Double Blind Trial ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Blind Trial ◽  
Objective Information ◽  
Homeopathic Medicine

Dowsing is a method of problem-solving that uses a motor automatism, amplified through a pendulum or similar device. In a homeopathic context, it is used as an aid to prescribing and as a tool to identify miasm or toxin load. A randomized double-blind trial was conducted to determine whether six dowsing homeopaths were able to distinguish between Bryonia in a 12c potency and placebo by use of dowsing alone. The homeopathic medicine Bryonia was correctly identified in 48.1% of bottle pairs (n=156; 95% confidence interval 40.2%, 56.0%; P=0.689). These results, wholly negative, add to doubts whether dowsing in this context can yield objective information.

Double-Blind Trial of Aminophylline in Status Asthmaticus

PEDIATRICS ◽  
1971 ◽  
Vol 48 (4) ◽  
pp. 642-646
Author(s):  
William E. Pierson ◽  
C. Warren Bierman ◽  
Stanley J. Stamm ◽  
Paul P. VanArsdel
Keyword(s):  
Adverse Effects ◽  
Therapeutic Effect ◽  
Status Asthmaticus ◽  
Controlled Trial ◽  
Hospitalized Children ◽  
Double Blind Trial ◽  
Ventilatory Function ◽  
Double Blind ◽  
Medical Supervision ◽  
Blind Trial

Significant improvement in ventilatory function without observable adverse effects has been demonstrated by this double-blind controlled trial of intravenous aminophylline in status asthmaticus. Aminophylline appears to have a beneficial therapeutic effect when given in addition to other accepted medications in appropriate dosage and under careful medical supervision to hospitalized children with status asthmaticus.

A Double-Blind Trial: Vivalan against Placebo in Depressed Elderly Patients

1980 ◽  
Vol 8 (1) ◽  
pp. 18-21 ◽  
Author(s):  
L Knorring Von
Keyword(s):  
Elderly Patients ◽  
Cardiac Disease ◽  
Depressive Illness ◽  
Primary Diagnosis ◽  
Controlled Study ◽  
Double Blind Trial ◽  
Double Blind ◽  
Blind Trial ◽  
Depressed Patients ◽  
Depression Ratings

A double-blind controlled study of viloxazine against placebo in elderly depressed patients with a primary diagnosis of depressive illness records statistically significant improvements in depression ratings in the viloxazine group after three weeks. Viloxazine was effective and well tolerated at doses of 100 to 200 mg in depressed elderly patients, several of whom had concurrent cardiac disease.

A Controlled Trial of Prothipendyl (Tolnate) in Mentally Subnormal Patients

1966 ◽  
Vol 112 (482) ◽  
pp. 95-100 ◽  
Author(s):  
Margaret E. McKenzie ◽  
Daphne Roswell-Harris
Keyword(s):  
Side Effects ◽  
Controlled Trial ◽  
Double Blind Trial ◽  
Double Blind ◽  
Blind Trial ◽  
Preliminary Group

The improvement shown by a group of severely subnormal patients after treatment with prothipendyl (Tolnate) was the reason for conducting a double-blind trial to assess the effects of the drug, while attempts were made to control the environment. The preliminary group studied consisted of 35 patients of both sexes, of all ages, who all exhibited pronounced behaviour disorders and presented acute problems in nursing and management. None had responded adequately to the more widely used tranquillizers and sedatives, but all except two patients with superadded depression, responded to prothipendyl in some measure without side effects.

Lithium Continuation Therapy Following Electroconvulsive Therapy

1981 ◽  
Vol 139 (4) ◽  
pp. 284-287 ◽  
Author(s):  
A. Coppen ◽  
M. T. Abou-Saleh ◽  
P. Milln ◽  
J. Bailey ◽  
M. Metcalfe ◽  
...  
Keyword(s):  
Electroconvulsive Therapy ◽  
Depressive Illness ◽  
High Rate ◽  
Double Blind Trial ◽  
Double Blind ◽  
Blind Trial ◽  
Clinical Recovery ◽  
Continuation Therapy ◽  
One Year ◽  
To Receive

SummaryThirty-eight depressed patients who were treated with ECT were randomly assigned to receive lithium therapy or identical-looking placebo tablets for one year after clinical recovery in a double-blind trial. The patients who received placebo tablets spent an average of 7.8 weeks with an episode of depression (either as in-patients or day-patients) during the year. In comparison, patients who received lithium spent on average 1.7 weeks with an episode (P <0.02). The trial confirms the high rate of relapses after ECT and suggests that lithium considerably reduces this morbidity. It is suggested that ECT without continuation therapy is not a satisfactory treatment of depressive illness.

Double-Blind Trial of the New Analgesic and Anti-Inflammatory Drug Indoprofen in Post-Episiotomic Pain

1975 ◽  
Vol 3 (1) ◽  
pp. 16-20 ◽  
Author(s):  
S Pedronetto ◽  
F Gorini ◽  
V Mandelli ◽  
L M Fuccella
Keyword(s):  
Side Effects ◽  
Controlled Trial ◽  
Double Blind Trial ◽  
Analgesic Drug ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Inflammatory Drug ◽  
Blind Trial ◽  
Anti Inflammatory

A double-blind, placebo-controlled trial of indoprofen, a new anti-inflammatory and analgesic drug, was carried out in women with pain due to episiotomy. A single 100 mg dose of the drug proved to be significantly more active than placebo in decreasing pain and was devoid of any side-effects.

Acute and continuation risperidone monotherapy in bipolar mania: a 3-week placebo-controlled trial followed by a 9-week double-blind trial of risperidone and haloperidol

2005 ◽  
Vol 15 (1) ◽  
pp. 75-84 ◽  
Author(s):  
Anatoly B. Smulevich ◽  
Sumant Khanna ◽  
Mariëlle Eerdekens ◽  
Keith Karcher ◽  
Michelle Kramer ◽  
...  
Keyword(s):  
Controlled Trial ◽  
Double Blind Trial ◽  
Double Blind ◽  
Blind Trial ◽  
Bipolar Mania
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