Hebephrenia is dead, long live hebephrenia, or why Hecker and Chaslin were on to something

2019 ◽  
Vol 25 (6) ◽  
pp. 373-376 ◽  
Author(s):  
Alvaro Barrera ◽  
Owen Curwell-Parry ◽  
Marie-Claire Raphael
Keyword(s):  
Mental Illness ◽  
Differential Diagnosis ◽  
Personality Disorder ◽  
Emotional Expression ◽  
Early Onset ◽  
Clinical Presentation ◽  
Severe Form ◽  
Thought Disorder ◽  
Formal Thought Disorder ◽  
Dsm 5

SUMMARYSince its first description in 1863, ‘hebephrenia’ has highlighted a group of patients characterised by an early onset of illness, formal thought disorder, bizarre behaviour and incongruent emotional expression. A proportion of patients with the most severe form of mental illness have a clinical presentation that is best captured by this diagnosis. Here, we outline the construct of hebephrenia and two of its core overlapping constituent parts: bizarre behaviour and the disorganisation dimension. We argue that, despite the removal of hebephrenia (disorganised schizophrenia) from DSM-5, clinicians should consider it as a differential diagnosis, particularly in suspected personality disorder.

scholarly journals Normocytic Normochromic Anemia Revealed an Early Onset Hashimoto’s Hypothyroidism in an Infant: A Case Report

2021 ◽  
pp. 1-5
Author(s):  
Manal Mustafa Khadora ◽  
Maysa Saleh ◽  
Rawah Idres ◽  
Sura Ahmed Al-Doory ◽  
Mahmoud Ahmed Radaideh
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Autoimmune Thyroiditis ◽  
Subclinical Hypothyroidism ◽  
Early Onset ◽  
Clinical Presentation ◽  
Primary Hypothyroidism ◽  
Normocytic Normochromic Anemia ◽  
Wide Range ◽  
Normochromic Anemia

Autoimmune thyroiditis is very rare etiology of primary hypothyroidism in infancy. Hypothyroidism has a wide range of clinical presentation, from subclinical hypothyroidism to overt type. It is unclear what pathological mechanisms connect thyroid function and erythropoiesis or how thyroid disease can contribute to anemia. We report a 12-month-old infant who presented with anemia associated with early onset of overt autoimmune thyroiditis. The peculiarity of our case enables us to draw attention of physician to consider acquired hypothyroidism in the differential diagnosis of unexplained anemia even if the neonatal screening is normal and congenital hypothyroidism is a remote possibility.

scholarly journals Early Onset Marfan Syndrome: Atypical Clinical Presentation of Two Cases

2015 ◽  
Vol 18 (1) ◽  
pp. 71-76 ◽  
Author(s):  
Abdullah Ozyurt ◽  
A. Baykan ◽  
M. Argun ◽  
O. Pamukcu ◽  
H. Halis ◽  
...  
Keyword(s):  
Marfan Syndrome ◽  
Early Onset ◽  
Poor Prognosis ◽  
Clinical Presentation ◽  
Severe Form ◽  
Early Age ◽  
Newborn Period ◽  
Heart Failure Treatment ◽  
Failure Treatment ◽  
Atypical Clinical Presentation

Abstract Early onset Marfan Syndrome (eoMFS) is a rare, severe form of Marfan Syndrome (MFS). The disease has a poor prognosis and most patients present with resistance to heart failure treatment during the newborn period. This report presents two cases of eoMFS with similar clinical features diagnosed in the newborn period and who died at an early age due to the complications related to the involvement of the cardiovascular system.

scholarly journals Analysing Joker: an attempt to establish diagnosis for a film icon

2021 ◽  
pp. 1-4
Author(s):  
Valentin Yurievich Skryabin
Keyword(s):  
Traumatic Brain Injury ◽  
Mental Illness ◽  
Brain Injury ◽  
Personality Disorder ◽  
Mental Disorder ◽  
Psychotic Disorder ◽  
Narcissistic Personality Disorder ◽  
Dsm 5 ◽  
Narcissistic Personality ◽  
Unusual Combination

Summary Todd Phillips's film Joker, a 2019 psychological thriller, has stirred up strong reactions to the portrayal of the lead character's mental disorder, which is never specified. I used DSM-5 criteria to study whether Joker/Arthur Fleck showed signs of a real mental disorder. The psychopathology Arthur exhibits is unclear, preventing diagnosis of psychotic disorder or schizophrenia; the unusual combination of symptoms suggests a complex mix of features of certain personality traits, namely psychopathy and narcissism (he meets DSM-5 criteria for narcissistic personality disorder). He also shows the symptoms of pseudobulbar affect due to traumatic brain injury. This apparent co-occurrence of both mental disorder and a neurological condition may be confusing for audiences trying to understand mental illness.

A Comparative Study of 470 Cases of Early-Onset and Late-Onset Schizophrenia

1993 ◽  
Vol 163 (3) ◽  
pp. 352-357 ◽  
Author(s):  
Robert Howard ◽  
David Castle ◽  
Simon Wessely ◽  
Robin Murray
Keyword(s):  
Early Onset ◽  
Late Onset ◽  
Age At Onset ◽  
Thought Disorder ◽  
Auditory Hallucinations ◽  
Formal Thought Disorder ◽  
Persecutory Delusions ◽  
Affective Symptoms ◽  
Third Person ◽  
Organic Psychoses

The presence or absence of 22 schizophrenic symptoms was recorded with the age at onset of illness in 470 patients with non-affective, non-organic psychoses. Positive and negative formal thought disorder, affective symptoms, inappropriate affect, delusions of grandiosity or passivity, primary delusions other than delusional perception, and thought insertion and withdrawal were all more common in early-onset cases (age at onset 44 years or less;n= 336). Persecutory delusions with and without hallucinations, organised delusions, and third-person, running commentary and accusatory or abusive auditory hallucinations were all more common in late-onset cases (age at onset 45 years or more;n= 134). There was no difference between cases of early and late onset in the prevalence of delusions of reference, bizarre delusions, delusional perception, or lack of insight. We conclude that although there are clinical similarities between cases of schizophrenia with early and late onset, there are sufficient differences between them to suggest that they are not phenotypically homogeneous.

scholarly journals S112. RELATION BETWEEN EARLY-ONSET PSYCHOSIS AND FORMAL THOUGHT DISORDER IN SCHIZOPHRENIA

2018 ◽  
Vol 44 (suppl_1) ◽  
pp. S368-S368
Author(s):  
Koksal Alptekin ◽  
Simge Altinok ◽  
Halis Ulas ◽  
Banu Degirmencioglu ◽  
Berna Akded
Keyword(s):  
Early Onset ◽  
Thought Disorder ◽  
Formal Thought Disorder ◽  
Early Onset Psychosis

scholarly journals A Practical Approach to Early-Onset Parkinsonism

2021 ◽  
pp. 1-26
Author(s):  
Giulietta M. Riboldi ◽  
Emanuele Frattini ◽  
Edoardo Monfrini ◽  
Steven J. Frucht ◽  
Alessio Di Fonzo
Keyword(s):  
Differential Diagnosis ◽  
Early Onset ◽  
Clinical Presentation ◽  
Late Onset ◽  
Correct Diagnosis ◽  
Disease Onset ◽  
Practical Approach ◽  
Juvenile Onset ◽  
Laboratory Findings ◽  
Work Planning

Early-onset parkinsonism (EO parkinsonism), defined as subjects with disease onset before the age of 40 or 50 years, can be the main clinical presentation of a variety of conditions that are important to differentiate. Although rarer than classical late-onset Parkinson’s disease (PD) and not infrequently overlapping with forms of juvenile onset PD, a correct diagnosis of the specific cause of EO parkinsonism is critical for offering appropriate counseling to patients, for family and work planning, and to select the most appropriate symptomatic or etiopathogenic treatments. Clinical features, radiological and laboratory findings are crucial for guiding the differential diagnosis. Here we summarize the most important conditions associated with primary and secondary EO parkinsonism. We also proposed a practical approach based on the current literature and expert opinion to help movement disorders specialists and neurologists navigate this complex and challenging landscape.

Relation between early-onset psychosis and formal thought disorder in schizophrenia

2019 ◽  
Vol 29 ◽  
pp. S130
Author(s):  
S. Altinok ◽  
K. Alptekin ◽  
H. Ulas ◽  
B. Yalincetin ◽  
B. Degirmencioglu ◽  
...  
Keyword(s):  
Early Onset ◽  
Thought Disorder ◽  
Formal Thought Disorder ◽  
Early Onset Psychosis

scholarly journals Clinical presentation, differential diagnosis and management of bipolar disorder in children and adolescents: a review

2021 ◽  
Vol 8 (11) ◽  
pp. 1769
Author(s):  
Jeplin Bez
Keyword(s):  
Bipolar Disorder ◽  
Mental Illness ◽  
Differential Diagnosis ◽  
Children And Adolescents ◽  
20Th Century ◽  
Clinical Presentation ◽  
Adult Population ◽  
Age Group ◽  
Children And Adolescent ◽  
Management Approaches

Bipolar disorder is a mental illness that causes serious disabilities in both social and work function. The occurrence of this disorder in children and adolescent age group has gained the attention of research workers since the 20th century. The varied clinical presentation of this disorder in comparison to the adult population, as well as the management approaches have been a matter of debate for ages. The aim of the study was to put forward the diagnostic and treatment approaches of bipolar disorder in children and adolescent.

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