The computingmethod forthe safety boundary of obstacle in complex area

2018 ◽  
Author(s):  
Ding Jianqun ◽  
Li Weibo ◽  
He Yongqing ◽  
Guan Yezhi ◽  
Bai Zhihong
Keyword(s):  
Safety Boundary

F.04 Flow diversion in the treatment of aneurysms: A randomized care trial and registry

2016 ◽  
Vol 43 (S2) ◽  
pp. S19-S19
Author(s):  
T Darsaut ◽  
J Gentric ◽  
D Iancu ◽  
M Chow ◽  
J Rempel ◽  
...  
Keyword(s):  
Primary Outcome ◽  
Standard Treatment ◽  
Flow Diversion ◽  
Parent Vessel ◽  
Vessel Occlusion ◽  
Safety Outcome ◽  
Standard Management ◽  
Efficacy Outcome ◽  
Parent Vessel Occlusion ◽  
Safety Boundary

Background: The Flow diversion in the treatment of Intracranial Aneurysm (FIAT) trial was designed to guide the clinical use of flow diversion. Methods: FIAT proposed randomized allocation flow diversion or standard management (observation, coiling, parent vessel occlusion, or clipping), and a registry of non-randomized patients treated with flow diversion. Primary safety outcome was death or dependency (mRS > 2) at 3 months. Primary efficacy outcome was angiographic occlusion at 3-12 months combined with independent clinical outcome. Results: Of 112 participating patients recruited, 78 were randomized, and 34 received flow diversion within the registry. The study was halted for safety concerns. Twelve of 73 patients (16.4%; CI [9.7% -26.7%]) who were allocated or received flow diversion at any time were dead (n=8) or dependent (n=4) at 3 months or more, crossing a predefined safety boundary. Death or dependency occurred in 5 of 36 patients randomly allocated flow diversion and in 5 of 36 patients allocated standard treatment (13.9%; [6.1%-28.7%]). Efficacy was below hypothesized expectations: 15 of 36 patients (41.7%; [27.1%-57.8%]) randomly allocated flow diversion failed to reach the primary outcome, as compared to 11 of 36 patients allocated standard treatment (30.1%; [18.0%-46.9%]). Conclusions: Flow diversion was not as safe and effective as hypothesized. More randomized trials are needed.

Study on safety boundary for high-speed train running in severe environments

2013 ◽  
Vol 1 (1-2) ◽  
pp. 87-108 ◽  
Author(s):  
Xuesong Jin ◽  
Xinbiao Xiao ◽  
Liang Ling ◽  
Li Zhou ◽  
Jiayang Xiong
Keyword(s):  
High Speed ◽  
High Speed Train ◽  
Severe Environments ◽  
Safety Boundary

Study on safety boundary of flow instability and CHF for parallel channels in motion

2018 ◽  
Vol 335 ◽  
pp. 219-230 ◽  
Author(s):  
Di Liu ◽  
Wenxi Tian ◽  
Mengmeng Xi ◽  
Ronghua Chen ◽  
Suizheng Qiu ◽  
...  
Keyword(s):  
Flow Instability ◽  
Parallel Channels ◽  
Safety Boundary
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