Prospective Surveillance and Risk Reduction of Cancer Treatment–Related Lymphedema: Systematic Review and Meta-Analysis

2020 ◽  
Vol 47 (5) ◽  
pp. E161-E170
Author(s):  
Jingyi Ding ◽  
Bashar Hasan ◽  
Konstantinos Malandris ◽  
Magdoleen Farah ◽  
Apostolos Manolopoulos ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cancer Treatment ◽  
Risk Reduction ◽  
Meta Analysis ◽  
Prospective Surveillance

scholarly journals Incidence of Oral Mucositis in Patients Undergoing Head and Neck Cancer Treatment: Systematic Review and Meta-Analysis

2021 ◽  
Vol 5 (1) ◽  
pp. 23
Author(s):  
Raquel Pacheco ◽  
Maria Alzira Cavacas ◽  
Paulo Mascarenhas ◽  
Pedro Oliveira ◽  
Carlos Zagalo
Keyword(s):  
Systematic Review ◽  
Head And Neck Cancer ◽  
Oral Health ◽  
Cancer Treatment ◽  
Head And Neck ◽  
Neck Cancer ◽  
Oral Mucositis ◽  
Negative Impact ◽  
Meta Analysis ◽  
Incidence Rates

This systematic review and meta-analysis aimed to assess the literature about the incidence of oral mucositis and its degrees (mild, moderate, and severe), in patients undergoing head and neck cancer treatment (radiotherapy, chemotherapy, and surgery). Addressing this issue is important since oral mucositis has a negative impact on oral health and significantly deteriorates the quality of life. Therefore, a multidisciplinary team, including dentists, should be involved in the treatment. The overall oral mucositis incidence was 89.4%. The global incidence for mild, moderate, and severe degrees were 16.8%, 34.5%, and 26.4%, respectively. The high incidence rates reported in this review point out the need for greater care in terms of the oral health of these patients.

Genetic variants associated with methotrexate-induced mucositis in cancer treatment: a systematic review and meta-analysis

2021 ◽  
pp. 103312
Author(s):  
Hedy Maagdenberg ◽  
Natanja Oosterom ◽  
Jolanda Zanen ◽  
Donato Gemmati ◽  
Rachael E. Windsor ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cancer Treatment ◽  
Genetic Variants ◽  
Meta Analysis

Early-rectal Cancer Treatment: A Decision-tree Making Based on Systematic Review and Meta-analysis

2021 ◽  
Vol 99 (2) ◽  
pp. 89-107
Author(s):  
Ignacio Aguirre-Allende ◽  
Jose Maria Enriquez-Navascues ◽  
Garazi Elorza-Echaniz ◽  
Ane Etxart-Lopetegui ◽  
Nerea Borda-Arrizabalaga ◽  
...  
Keyword(s):  
Systematic Review ◽  
Rectal Cancer ◽  
Decision Tree ◽  
Cancer Treatment ◽  
Meta Analysis ◽  
Early Rectal Cancer ◽  
Rectal Cancer Treatment

scholarly journals Mortality due to cancer treatment delay: systematic review and meta-analysis

BMJ ◽  
2020 ◽  
pp. m4087 ◽  
Author(s):  
Timothy P Hanna ◽  
Will D King ◽  
Stephane Thibodeau ◽  
Matthew Jalink ◽  
Gregory A Paulin ◽  
...  
Keyword(s):  
Systematic Review ◽  
Overall Survival ◽  
Confidence Interval ◽  
Cancer Treatment ◽  
Head And Neck ◽  
Adjuvant Radiotherapy ◽  
Systemic Treatment ◽  
Meta Analysis ◽  
Treatment Delay ◽  
Hazard Ratio

Abstract Objective To quantify the association of cancer treatment delay and mortality for each four week increase in delay to inform cancer treatment pathways. Design Systematic review and meta-analysis. Data sources Published studies in Medline from 1 January 2000 to 10 April 2020. Eligibility criteria for selecting studies Curative, neoadjuvant, and adjuvant indications for surgery, systemic treatment, or radiotherapy for cancers of the bladder, breast, colon, rectum, lung, cervix, and head and neck were included. The main outcome measure was the hazard ratio for overall survival for each four week delay for each indication. Delay was measured from diagnosis to first treatment, or from the completion of one treatment to the start of the next. The primary analysis only included high validity studies controlling for major prognostic factors. Hazard ratios were assumed to be log linear in relation to overall survival and were converted to an effect for each four week delay. Pooled effects were estimated using DerSimonian and Laird random effect models. Results The review included 34 studies for 17 indications (n=1 272 681 patients). No high validity data were found for five of the radiotherapy indications or for cervical cancer surgery. The association between delay and increased mortality was significant (P<0.05) for 13 of 17 indications. Surgery findings were consistent, with a mortality risk for each four week delay of 1.06-1.08 (eg, colectomy 1.06, 95% confidence interval 1.01 to 1.12; breast surgery 1.08, 1.03 to 1.13). Estimates for systemic treatment varied (hazard ratio range 1.01-1.28). Radiotherapy estimates were for radical radiotherapy for head and neck cancer (hazard ratio 1.09, 95% confidence interval 1.05 to 1.14), adjuvant radiotherapy after breast conserving surgery (0.98, 0.88 to 1.09), and cervix cancer adjuvant radiotherapy (1.23, 1.00 to 1.50). A sensitivity analysis of studies that had been excluded because of lack of information on comorbidities or functional status did not change the findings. Conclusions Cancer treatment delay is a problem in health systems worldwide. The impact of delay on mortality can now be quantified for prioritisation and modelling. Even a four week delay of cancer treatment is associated with increased mortality across surgical, systemic treatment, and radiotherapy indications for seven cancers. Policies focused on minimising system level delays to cancer treatment initiation could improve population level survival outcomes.

Volume-outcome associations in head and neck cancer treatment: A systematic review and meta-analysis

Head & Neck ◽  
2014 ◽  
Vol 36 (12) ◽  
pp. 1820-1834 ◽  
Author(s):  
Antoine Eskander ◽  
Mazin Merdad ◽  
Jonathan C. Irish ◽  
Stephen F. Hall ◽  
Patti A. Groome ◽  
...  
Keyword(s):  
Systematic Review ◽  
Head And Neck Cancer ◽  
Cancer Treatment ◽  
Head And Neck ◽  
Neck Cancer ◽  
Meta Analysis ◽  
Volume Outcome

The Effect of Resistance Training on Body Composition During and After Cancer Treatment: A Systematic Review and Meta-Analysis

2021 ◽  
Author(s):  
Briana Clifford ◽  
Sean Koizumi ◽  
Michael A. Wewege ◽  
Hayley B. Leake ◽  
Lauren Ha ◽  
...  
Keyword(s):  
Systematic Review ◽  
Body Composition ◽  
Resistance Training ◽  
Cancer Treatment ◽  
Meta Analysis ◽  
After Cancer
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