The effect of a lifestyle intervention on body weight, psychological health status and risk factors associated with disease recurrence in women recovering from breast cancer treatment

2013 ◽  
Author(s):  
John Saxton
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Body Weight ◽  
Health Status ◽  
Cancer Treatment ◽  
Lifestyle Intervention ◽  
Psychological Health ◽  
Disease Recurrence ◽  
Breast Cancer Treatment ◽  
Factors Associated

scholarly journals Probiotics for the Treatment of Docetaxel-Related Weight Gain of Breast Cancer Patients—A Single-Center, Randomized, Double-Blind, and Placebo-Controlled Trial

2021 ◽  
Vol 8 ◽  
Author(s):  
Zhang Juan ◽  
Zhang Qing ◽  
Liang Yongping ◽  
Liyuan Qian ◽  
Wei Wu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Body Weight ◽  
Weight Gain ◽  
Cancer Treatment ◽  
Cancer Patients ◽  
Body Fat ◽  
Breast Cancer Treatment ◽  
Body Fat Percentage ◽  
Breast Cancer Patients ◽  
Fat Percentage

Background: Docetaxel is an important chemotherapy-agent for breast cancer treatment. One of its side-effects is weight gain, which increases the all-cause mortality rate. Considering gut microbiota is one important factor for weight regulation, we hypothesized that probiotics could be potentially used to reduce the docetaxel-related weight gain in breast cancer patients.Methods: From 10/8/2018 to 10/17/2019, 100 breast cancer (Stage I-III) patients underwent four cycles of docetaxel-based chemotherapy were enrolled and randomly assigned to receive probiotics (Bifidobacterium longum, Lactobacillus acidophilus, and Enterococcus faecalis) or placebo (supplementary material of the probiotics capsule) treatment for 84 days with three capsules per time, twice/day. The primary outcome: the changes in body weight and body-fat percentage of the patients were measured by a designated physician using a fat analyzer, and the secondary outcomes: the fasting insulin, plasma glucose, and lipids were directly obtained from the Hospital Information System (HIS); The metabolites were measured using liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS); The fecal microbiome was analyzed using bacterial 16S ribosomal RNA (rRNA) gene sequence. All indicators were measured 1 day before the first cycle of docetaxel-based chemotherapy and 21 days after the last cycle of docetaxel-based chemotherapy.Results: Compared with the placebo group, the probiotic group showed significantly smaller changes in body weight (Mean [SD] 0.77 [2.58] vs. 2.70 [3.08], P = 0.03), body-fat percentage (Mean [SD] 0.04 [1.14] vs. 3.86 [11.09], P = 0.02), and low density lipoprotein (LDL) (Mean [SD]−0.05[0.68] vs. 0.39 [0.58], P = 0.002). Moreover, five of the 340 detected plasma metabolites showed significant differences between the two groups. The change of biliverdin dihydrochloride (B = −0.724, P = 0.02) was inverse correlated with weight gain. One strain of the phylum and three strains of the genus were detected to be significantly different between the two groups. Also, the changes of Bacteroides (B = −0.917, P < 0.001) and Anaerostipes (B = −0.894, P < 0.001) were inverse correlated with the change of LDL.Conclusions: Probiotics supplement during docetaxel-based chemotherapy for breast cancer treatment may help to reduce the increase in body weight, body-fat percentage, plasma LDL, and minimize the metabolic changes and gut dysbacteriosis.Clinical Trial Registration:http://www.chictr.org.cn/showproj.aspx?proj=24294, ChiCTR-INQ-17014181.

scholarly journals Identification and Management of Lymphedema in Patients With Breast Cancer

2019 ◽  
Vol 15 (5) ◽  
pp. 255-262 ◽  
Author(s):  
Pavankumar Tandra ◽  
Avyakta Kallam ◽  
Jairam Krishnamurthy
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Cancer Treatment ◽  
Early Stage ◽  
Financial Burden ◽  
Breast Cancer Treatment ◽  
Initial Diagnosis ◽  
Axillary Surgery ◽  
Incidence Risk ◽  
End Stage

Breast cancer–related lymphedema (BCRL) is a potentially debilitating and often irreversible complication of breast cancer treatment. Risk of BCRL is proportional to the extent of axillary surgery and radiation. Other risk factors include obesity and infections. Given the 5-year survival rate of 90% and its potential impact on the quality of life of survivors of breast cancer, BCRL has become a significant financial burden on the health care system. Minimizing axillary surgery and radiation has been proven to reduce the risk of BCRL. Comprehensive multidisciplinary assessment at the time of initial diagnosis; early referral to physical therapy after surgery; and patient education regarding weight loss, skin, and nail care are cornerstones of the management of early-stage lymphedema. End-stage lymphedema may benefit from referral to a plastic surgeon specializing in lymphedema surgery. In this review, we attempt to review the incidence, risk factors, staging, prevention, and management of this complication of breast cancer treatment. We also describe our multidisciplinary approach for the prevention of this complication at the time of initial diagnosis.

scholarly journals Risk factors, prevalence, and course of severe fatigue after breast cancer treatment: a meta-analysis involving 12 327 breast cancer survivors

2016 ◽  
Vol 27 (6) ◽  
pp. 965-974 ◽  
Author(s):  
H.J.G. Abrahams ◽  
M.F.M. Gielissen ◽  
I.C. Schmits ◽  
C.A.H.H.V.M. Verhagen ◽  
M.M. Rovers ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Cancer Survivors ◽  
Cancer Treatment ◽  
Breast Cancer Survivors ◽  
Meta Analysis ◽  
Breast Cancer Treatment ◽  
Severe Fatigue

Incidence and risk factors of lymphedema after breast cancer treatment: 10 years of follow-up

The Breast ◽  
2017 ◽  
Vol 36 ◽  
pp. 67-73 ◽  
Author(s):  
Ana Carolina Padula Ribeiro Pereira ◽  
Rosalina Jorge Koifman ◽  
Anke Bergmann
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Cancer Treatment ◽  
Breast Cancer Treatment

Risk factors of upper-arm lymphedema after breast cancer treatment

2017 ◽  
Vol 2 (1) ◽  
pp. 73
Author(s):  
Mokhtar Hamood ◽  
Yehia Safwat ◽  
Mohammed Shaalan ◽  
Mohsen Mokhtar
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Cancer Treatment ◽  
Breast Cancer Treatment ◽  
Upper Arm ◽  
Arm Lymphedema

Prevalence and risk factors of adhesive capsulitis of the shoulder after breast cancer treatment

2016 ◽  
Vol 25 (4) ◽  
pp. 1317-1322 ◽  
Author(s):  
Seoyon Yang ◽  
Dae Hwan Park ◽  
Sei Hyun Ahn ◽  
Jisun Kim ◽  
Jong Won Lee ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Cancer Treatment ◽  
Adhesive Capsulitis ◽  
Breast Cancer Treatment

scholarly journals Factors associated with wait times across the breast cancer treatment pathway in Ontario

SpringerPlus ◽  
2013 ◽  
Vol 2 (1) ◽  
pp. 388 ◽  
Author(s):  
Amalia Plotogea ◽  
Anna M Chiarelli ◽  
Lucia Mirea ◽  
Maegan V Prummel ◽  
Nelson Chong ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Treatment ◽  
Breast Cancer Treatment ◽  
Wait Times ◽  
Treatment Pathway ◽  
Factors Associated

scholarly journals Neuropathic Pain After Breast Cancer Treatment: Characterization and Risk Factors

2017 ◽  
Vol 54 (6) ◽  
pp. 877-888 ◽  
Author(s):  
Susana Pereira ◽  
Filipa Fontes ◽  
Teresa Sonin ◽  
Teresa Dias ◽  
Maria Fragoso ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Neuropathic Pain ◽  
Cancer Treatment ◽  
Breast Cancer Treatment
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