scholarly journals Development and validation of a robust automated analysis of plasma phospholipid fatty acids for metabolic phenotyping of large epidemiological studies

10.1186/gm443 ◽  
2013 ◽  
Vol 5 (4) ◽  
pp. 39 ◽  
Author(s):  
Laura Wang ◽  
Keith Summerhill ◽  
Carmen Rodriguez-Canas ◽  
Ian Mather ◽  
Pinal Patel ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Plasma Phospholipid ◽  
Automated Analysis ◽  
Epidemiological Studies ◽  
Phospholipid Fatty Acids ◽  
Metabolic Phenotyping ◽  
Development And Validation

scholarly journals Validation of a FFQ to estimate the intake of PUFA using plasma phospholipid fatty acids and weighed foods records

2007 ◽  
Vol 97 (3) ◽  
pp. 561-568 ◽  
Author(s):  
S. A. McNaughton ◽  
M. C. Hughes ◽  
G. C. Marks
Keyword(s):  
Fatty Acids ◽  
Dietary Intake ◽  
Controlled Trial ◽  
Dietary Assessment ◽  
Plasma Phospholipid ◽  
Docosapentaenoic Acid ◽  
Phospholipid Fatty Acids ◽  
Food Record ◽  
Dietary Assessment Methods ◽  
Randomised Controlled

Due to the growing knowledge about the role of specific fatty acids in health and disease, dietary intake measurements of individual fatty acids or classes of fatty acids are becoming increasingly important. The objective of this study was to evaluate the ability of the Nambour FFQ to estimate intakes of specific fatty acids, particularly PUFA. The study population was a sub-sample of adult participants in a randomised controlled trial of β-carotene and sunscreen in the prevention of skin cancer (n43). Dietary intake was assessed by a self-administered FFQ and a weighed food record (WFR). Non-fasting blood samples were collected and analysed for plasma phospholipid fatty acids. Median intakes on the FFQ were generally higher than the WFR except for then-3 PUFA groups, where the FFQ estimated higher intakes. Correlations between the FFQ and WFR were moderate (r0·32–0·59) except fortransfatty acids (r0·03). Correlations between each of the dietary assessment methods and the plasma phospholipids were poor for all fatty acids other than the PUFA. Using the methods of triads approach, the FFQ validity coefficients for totaln-3 fatty acids, total long chainn-3 fatty acids, EPA, arachidonic acid, docosapentaenoic acid and DHA were 0·50, 0·63, 0·45 and 0·62 and 0·62, respectively. For most fatty acids, the FFQ adequately estimates group mean fatty acid intakes and can adequately rank individuals; however, the ability of this FFQ to estimatetransfatty acids was poor.

Effects of two types of fish oil supplements on serum lipids and plasma phospholipid fatty acids in coronary artery disease

1990 ◽  
Vol 66 (17) ◽  
pp. 1171-1175 ◽  
Author(s):  
Gregg J. Reis ◽  
David I. Silverman ◽  
Theresa M. Boucher ◽  
Mary Ellen Sipperly ◽  
Gary L. Horowitz ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Fatty Acids ◽  
Coronary Artery ◽  
Fish Oil ◽  
Serum Lipids ◽  
Plasma Phospholipid ◽  
Phospholipid Fatty Acids ◽  
Artery Disease
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