scholarly journals Perioperative risk factors for serious gastrointestinal complications treated by laparotomy after cardiac surgery using cardiopulmonary bypass

Critical Care ◽  
2011 ◽  
Vol 15 (S1) ◽  
Author(s):  
P Soos ◽  
B Schmack ◽  
A Weymann ◽  
G Veres ◽  
B Merkely ◽  
...  
2015 ◽  
Vol 2015 ◽  
pp. 1-12 ◽  
Author(s):  
Nikil Patel ◽  
Jatinder S. Minhas ◽  
Emma M. L. Chung

Modern day cardiac surgery evolved upon the advent of cardiopulmonary bypass machines (CPB) in the 1950s. Following this development, cardiac surgery in recent years has improved significantly. Despite such advances and the introduction of new technologies, neurological sequelae after cardiac surgery still exist. Ischaemic stroke, delirium, and cognitive impairment cause significant morbidity and mortality and unfortunately remain common complications. Postoperative cognitive decline (POCD) is believed to be associated with the presence of new ischaemic lesions originating from emboli entering the cerebral circulation during surgery. Cardiopulmonary bypass was thought to be the reason of POCD, but randomised controlled trials comparing with off-pump surgery show contradictory results. Attention has now turned to the growing evidence that perioperative risk factors, as well as patient-related risk factors, play an important role in early and late POCD. Clearly, identifying the mechanism of POCD is challenging. The purpose of this systematic review is to discuss the literature that has investigated patient and perioperative risk factors to better understand the magnitude of the risk factors associated with POCD after cardiac surgery.


2005 ◽  
Vol 62 (1) ◽  
pp. 64-70 ◽  
Author(s):  
Gopal C. Kowdley ◽  
Shishir Maithal ◽  
Shafqat Ahmed ◽  
David Naftel ◽  
Robert Karp

2016 ◽  
Vol 101 (11) ◽  
pp. 1010-1016 ◽  
Author(s):  
Julia K Gunn ◽  
John Beca ◽  
Rodney W Hunt ◽  
Michelle Goldsworthy ◽  
Christian P Brizard ◽  
...  

ObjectiveHistorical cohort studies have reported adverse neurodevelopment following cardiac surgery during early infancy. Advances in surgical techniques and perioperative care have coincided with updating of neurodevelopmental assessment tools. We aimed to determine perioperative risk factors for impaired neurodevelopment at 2 years following surgery for congenital heart disease (CHD) in early infancy.Design and patientsWe undertook a prospective longitudinal study of 153 full-term infants undergoing surgery for CHD before 2 months of age. Infants were excluded if they had a genetic syndrome associated with neurodevelopmental impairment.Outcome measuresPredefined perioperative parameters were recorded and infants were classified according to cardiac anatomy. At 2 years, survivors were assessed using the Bayley Scales of Infant Development-III.ResultsAt 2 years, 130 children (98% of survivors) were assessed. Mean cognitive, language and motor scores were 93.4±13.6, 93.6±16.1 and 96.8±12.5 respectively (100±15 norm). Twenty (13%) died and 12 (9%) survivors had severe impairment (score <70), mostly language (8%). The lowest scores were in infants born with single ventricle physiology with obstruction to the pulmonary circulation who required a neonatal systemic-to-pulmonary artery shunt. Additional risk factors for impairment included reduced gestational age, postoperative elevation of lactate or S100B and repeat cardiac surgery.ConclusionsIn the modern era of infant cardiac surgery and perioperative care, children continue to demonstrate neurodevelopmental delays. The use of updated assessment tools has revealed early language dysfunction and relative sparing of motor function. Ongoing follow-up is critical in this high-risk population.


2020 ◽  
Vol 24 (2) ◽  
pp. 83
Author(s):  
V. V. Pasyuga ◽  
D. A. Demin ◽  
I. L. Nudel ◽  
E. V. Demina ◽  
A. V. Kadykova ◽  
...  

<p><strong>Aim.</strong> This study was conducted to determine the incidence of delirium after cardiac surgery and its effect on the length of the patient’s stay in the ICU and to identify the perioperative risk factors.<br /><strong>Methods.</strong> This research was a retrospective assessment of 1941 medical records and the course of the perioperative period in patients subjected to elective cardiac surgery.<br /><strong>Results.</strong> Delirium developed in 193 cases (9.94%); whereas, hyperactive, hypoactive and mixed delirium was observed in 13%, 43% and 44% of the patients, respectively. Most often (26% of the cases), delirium occurred after complex combined surgeries. Independent risk factors for the development of delirium were older age (OR 1.041, 95% CI [1.002–1.081], p = 0.038), EuroSCORE II score (OR 1.286, 95% CI [1.093–1.731], p = 0.025), acute kidney injury (OR 1.306, 95% CI [1.107–1.942], p = 0.0018) and renal replacement therapy (OR 1.399 95% CI [1.361–2.792], p = 0.001). Cardiopulmonary bypass duration and time of clamping of the aorta, postoperative serum creatinine level, need for blood transfusions and duration of mechanical ventilation and duration of ICU stay were identified as predictors and were also significantly higher in the delirium group. Delirium was closely associated with critical illness polyneuropathy (OR 9.201, 95% CI [2.13–38.826], p &lt; 0.001) and neurogenic dysphagia (OR 7.48, 95% CI [1.12–56.07], p = 0.022).<br /><strong>Conclusion.</strong> The key factors for delirium development in the postoperative period include advanced age, high EuroSCORE II scale and acute kidney injury requiring continuous renal replacement therapy. Delirium significantly increases the duration of mechanical ventilation and the duration of ICU stay.</p><p>Received 30 January 2020. Revised 18 March 2020. Accepted 24 March 2020.</p><p><strong>Funding:</strong> The study did not have sponsorship.</p><p><strong>Conflict of interest:</strong> Authors declare no conflict of interest.</p><p><strong>Author contributions</strong><br />Conception and design: V.V. Pasyuga, I.N. Leiderman<br />Data collection: D.A. Demin, E.V. Demina, I.L. Nudel, V.V. Pasyuga <br />Data analysis: V.V. Pasyuga, I.N. Leiderman, D.A. Demin, D.G. Tarasov<br />Drafting the article: V.V. Pasyuga, D.A. Demin<br />Critical revision of the article: I.N. Leiderman, A.V. Kadykova<br />Final approval of the version to be published: V.V. Pasyuga, D.A. Demin, I.L. Nudel, E.V. Demina, A.V. Kadykova, D.G. Tarasov, I.N. Leiderman</p>


2020 ◽  
Vol 36 (1) ◽  
pp. 88 ◽  
Author(s):  
Surbhi Gupta ◽  
RoshanJoseph Fernandes ◽  
JosephSushil Rao ◽  
Radhika Dhanpal

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