scholarly journals Usefulness of open lung biopsy in mechanically ventilated patients with undiagnosed diffuse pulmonary infiltrates: influence of comorbidities and organ dysfunction

Critical Care ◽  
2007 ◽  
Vol 11 (4) ◽  
pp. R93 ◽  
Author(s):  
Seong Lim ◽  
Gee Suh ◽  
Jae Choi ◽  
Won Koh ◽  
Si Lim ◽  
...  
Keyword(s):  
Organ Dysfunction ◽  
Lung Biopsy ◽  
Open Lung Biopsy ◽  
Mechanically Ventilated ◽  
Mechanically Ventilated Patients ◽  
Open Lung ◽  
Pulmonary Infiltrates ◽  
Ventilated Patients

The Impact of Open Lung Biopsy on Diffuse Pulmonary Infiltrates in Patients with AIDS

2009 ◽  
Vol 75 (2) ◽  
pp. 157-162
Author(s):  
Chao-hsiang Lee ◽  
Jang-ming Lee ◽  
Chien-ching Hung ◽  
Pei-ming Huang ◽  
Shunn-wen Kuo ◽  
...  
Keyword(s):  
Lung Biopsy ◽  
Pulmonary Infiltrate ◽  
Therapeutic Benefit ◽  
Open Lung Biopsy ◽  
University Hospital ◽  
Severe Illness ◽  
Open Lung ◽  
Pulmonary Infiltrates ◽  
Prolonged Air Leak ◽  
The Impact

The evidence concerning open lung biopsy (OLB) for diffuse pulmonary infiltrates in patients with AIDS is limited. This study retrospectively evaluated the diagnostic and therapeutic yields of OLB compared with bronchoscopy for patients with AIDS with diffuse pulmonary infiltrate treated in the National Taiwan University Hospital from 1997 to 2004. There were 15 and 46 patients enrolled in the OLB and bronchoscopic groups in this study, respectively. As compared with the bronchoscopic group, patients from the OLB group had a higher chance of acquiring a specific diagnosis and possible change of therapy (73 vs 32.6% and 60 vs 21.7%, respectively; P < 0.05). There were two (13.3%) patients with prolonged air leak (greater than 7 days) in the OLB group, whereas four patients (8.7%) had procedure-related complications in the bronchoscopic group. There was no procedure-related mortality in the OLB group. This study demonstrated that OLB can be safely performed in select patients and provide a superior diagnostic and therapeutic benefit compared with bronchoscopy for diffuse pulmonary infiltrates in patients with AIDS. This procedure should be performed early in the clinical course to avoid irreversible clinical deterioration of the patients with severe illness.

Diffuse pulmonary infiltrates after bone marrow transplantation: the role of open lung biopsy

2004 ◽  
Vol 78 (1) ◽  
pp. 267-272 ◽  
Author(s):  
Jann-Yuan Wang ◽  
Yih-Leong Chang ◽  
Li-Na Lee ◽  
Jen-Hau Chen ◽  
Jih-Luh Tang ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Marrow Transplantation ◽  
Lung Biopsy ◽  
Open Lung Biopsy ◽  
Open Lung ◽  
Pulmonary Infiltrates
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