scholarly journals Association between interleukin-10 (IL-10) gene promoter polymorphisms and outcome in acetaminophen induced acute liver failure requiring admission to a liver intensive care unit

Critical Care ◽  
10.1186/cc556 ◽  
1999 ◽  
Vol 3 (Suppl 1) ◽  
pp. P183
Author(s):  
N Jackson ◽  
S Cookson ◽  
W Bernal ◽  
J Wendon ◽  
P Donaldson
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Gene Promoter ◽  
Interleukin 10 ◽  
Promoter Polymorphisms

A STUDY ON ETIOLOGY, CLINICAL FEATURES, MANAGEMENT AND OUTCOME OF ACUTE LIVER FAILURE IN PAEDIATRIC INTENSIVE CARE UNIT OF BURDWAN MEDICAL COLLEGE

2021 ◽  
pp. 54-55
Author(s):  
Sankar narayan mishra ◽  
Kaustav nayek ◽  
Tamal kayal ◽  
Debarshi Jana
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Pediatric Intensive Care Unit ◽  
Clinical Features ◽  
Paediatric Intensive Care Unit ◽  
Pediatric Intensive Care ◽  
Medical College ◽  
Bacterial Peritonitis

Introduction: In the present study, etiology, important clinical features, management and outcome of acute liver failure in children admitted in Pediatric Intensive Care Unit (PICU) of BURDWAN MEDICALCOLLEGE, WB are studied. Aims and objectives:To study different clinical features among those children having acute liver failure. I. To study the management and outcome of those children with acute liver failure in the Pediatric Intensive Care Unit. Material and methods: Pediatric Intensive Care Unit of BURDWAN MEDICALCOLLEGE, WB. 1 Year [December 2019 to November 2020]. Patients from 3months of age to 12years of age are eligible for enrolment if they meet the following criteria. Conclusion: Present study showed that cerebral edema was signicantly associated with mortality whereas AKI and spontaneous bacterial peritonitis were not signicantly related with mortality. Mean TSB and Prothrobin Time were higher but mean serum albumin was lower in those cases that had died.

scholarly journals Acute liver failure (ALF) in a specialist intensive care unit: a 7 year experience

Critical Care ◽  
10.1186/cc279 ◽  
1998 ◽  
Vol 2 (Suppl 1) ◽  
pp. P150 ◽  
Author(s):  
AJ Ellis ◽  
A Rhodes ◽  
N Jackson ◽  
JG O'Grady ◽  
PM Harrison ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Liver Failure ◽  
Acute Liver Failure

Epidemiology of Infections in Patients With Acute Liver Failure in the Intensive Care Unit

CHEST Journal ◽  
2013 ◽  
Vol 144 (4) ◽  
pp. 380A
Author(s):  
Radhika Zopey ◽  
Alexander Zider ◽  
Ronak Garg ◽  
Scott Hu ◽  
Tisha Wang ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Liver Failure ◽  
Acute Liver Failure

scholarly journals Clinical and Demographic Profiles of Children Presenting with Acetaminophen Induced Acute Liver Failure in a Tertiary Paediatric Intensive Care Unit of South India

2021 ◽  
Vol 41 (1) ◽  
pp. 23-28
Author(s):  
Puja Amatya ◽  
Sudeep Kumar Kapalavai ◽  
Ravi Kumar Krupanandan ◽  
Kalaimaran Sadasivam ◽  
Srinivas Sankaranarayanan ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Paediatric Intensive Care Unit ◽  
South India ◽  
Paediatric Population ◽  
Paediatric Intensive Care ◽  
Average Dose ◽  
Demographic Profiles

Introduction: Acetaminophen (APAP) is the most widely used over-the-counter antipyretic and analgesic medicine in children. Although hepatic failure and death is rare in paediatric population, it is one of the most important and dangerous presentation of acetaminophen induced toxicity in children. There is very sparse data regarding APAP induced paediatric acute liver failure in our settings, hence this study was done to know the clinical and demographic profiles as well as outcome of children with APAP induced acute liver failure. Methods: This was a retrospective study done in children aged 0 - 18 years admitted with the diagnosis of acetaminophen induced acute liver failure in a tertiary paediatric intensive care unit of South India from January 2014 to December 2018. The clinical, demographic profiles and outcome of these patients were reviewed and analysed. Results: A total of 26 children had acetaminophen induced acute liver failure. Out of 26 patients, 53.8% were males and 46.1% were females. Among these, 24 (92.3%) survived and two (7.7%) died. The average dose of acetaminophen ingested was 168.5 mg/ kg/d. The mean serum acetaminophen level was 52.3 mg/dl. The presence of low pH, hypotension and international normalised ratio (INR) value of > 4 showed bad outcome in children with acetaminophen induced acute liver failure. Conclusion: Paracetamol induced acute liver failure is rare but fatal presentation in children. Children with acidosis, shock and INR value of > 4 had poor prognosis. Hence, judicious use of different preparations as well as counselling to parents regarding use of appropriate doses in children should be done while prescribing this medicine.

scholarly journals 994 DEVELOPMENT AND PILOT OF A CHECKLIST FOR MANAGEMENT OF ACUTE LIVER FAILURE IN THE INTENSIVE CARE UNIT

2013 ◽  
Vol 58 ◽  
pp. S410
Author(s):  
O.K. Fix ◽  
I. Liou ◽  
C. Karvellas ◽  
D. Ganger ◽  
K.A. Forde ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Liver Failure ◽  
Acute Liver Failure

Factors associated with outcome in acute liver failure in an intensive care unit

2012 ◽  
Vol 32 (3) ◽  
pp. 172-178 ◽  
Author(s):  
Banani Poddar ◽  
Saurabh Saigal ◽  
Anand Kumar ◽  
Ratender K. Singh ◽  
Afzal Azim ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Factors Associated

scholarly journals 625 Development and Pilot of a Checklist for Management of Acute Liver Failure in the Intensive Care Unit

2013 ◽  
Vol 144 (5) ◽  
pp. S-956
Author(s):  
Oren K. Fix ◽  
Iris Liou ◽  
Constantine Karvellas ◽  
Daniel Ganger ◽  
Kimberly A. Forde ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Liver Failure ◽  
Acute Liver Failure
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