scholarly journals Prospective, randomized trial comparing fluids and dobutamine optimization of oxygen delivery in high-risk surgical patients [ISRCTN42445141]

Critical Care ◽  
2006 ◽  
Vol 10 (3) ◽  
Author(s):  
Suzana M Lobo ◽  
Francisco R Lobo ◽  
Carlos A Polachini ◽  
Daniela S Patini ◽  
Adriana E Yamamoto ◽  
...  
Critical Care ◽  
2005 ◽  
Vol 9 (S1) ◽  
Author(s):  
S Lobo ◽  
F Lobo ◽  
C Polachini ◽  
D Patini ◽  
K Andraus ◽  
...  

Critical Care ◽  
10.1186/cc514 ◽  
1999 ◽  
Vol 3 (Suppl 1) ◽  
pp. P140
Author(s):  
SMA Lobo ◽  
PS Fialho ◽  
AA Borim ◽  
SLA Brienzc ◽  
VG Castilho ◽  
...  

1997 ◽  
Vol 23 (1) ◽  
pp. 85-90 ◽  
Author(s):  
J. F. Guest ◽  
O. Boyd ◽  
W. M. Hart ◽  
R. M. Grounds ◽  
E. D. Bennett

PEDIATRICS ◽  
1978 ◽  
Vol 61 (6) ◽  
pp. 940-940
Author(s):  
Peter Camfield ◽  
Carol Camfield

The riddle of febrile seizures is that despite their high risk of recurrence (35% to 50%), the natural history of the disorder is benign for the vast majority of children.1 If daily phenobarbital administration for several years is to be recommended after the first febrile seizure, it must be shown to be exceedingly effective and safe. The commendable study of Woff et al. is the second2 prospective randomized trial with concurrent controls of the efficacy of phenobarbital to prevent recurrent febrile seizures.


This case focuses on increasing the amount of oxygen delivered to the surgical patient during the perioperative period by asking the question: Does the deliberate increase in oxygen delivery with the use of perioperative dopexamine reduce mortality and morbidity in high-risk surgical patients? Dopexamine is a dopamine analogue that produces peripheral vasodilation and an increase in cardiac index without significant increases in myocardial oxygen consumption. High-risk surgical patients were randomized to control or protocol limbs of the study. This randomized controlled study demonstrated a significant reduction in mortality and morbidity when dopexamine was used to increase oxygen delivery during the perioperative period in high-risk surgical patients.


2009 ◽  
pp. 654-664
Author(s):  
S. M. Lobo ◽  
E. Rezende ◽  
F. Suparregui Dias

2016 ◽  
Vol 25 (9) ◽  
pp. 1326-1332 ◽  
Author(s):  
Nicholas M. Donin ◽  
Allan Pantuck ◽  
Pia Klöpfer ◽  
Paul Bevan ◽  
Barbara Fall ◽  
...  

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