scholarly journals Noninvasive mechanical ventilation (NIMV) in weaning failure: could be an alternative approach?

Critical Care ◽  
10.1186/cc402 ◽  
1999 ◽  
Vol 3 (Suppl 1) ◽  
pp. P027
Author(s):  
A Esquinas ◽  
D González ◽  
A Carrillo ◽  
M Del Baño ◽  
M Rodríguez ◽  
...  
2021 ◽  
Vol 66 (2) ◽  
pp. 246-253
Author(s):  
Szymon Skoczyński ◽  
Maciej Ogonowski ◽  
Ewelina Tobiczyk ◽  
Damian Krzyżak ◽  
Grzegorz Brożek ◽  
...  

2013 ◽  
Vol 60 (5) ◽  
pp. 1234-1240 ◽  
Author(s):  
G. G. Rodrigues ◽  
U. S. Freitas ◽  
D. Bounoiare ◽  
L. A. Aguirre ◽  
C. Letellier

2021 ◽  
Vol 49 (5) ◽  
pp. 030006052110100
Author(s):  
Ju Gong ◽  
Bibo Zhang ◽  
Xiaowen Huang ◽  
Bin Li ◽  
Jian Huang

Objective Clinicians cannot precisely determine the time for withdrawal of ventilation. We aimed to evaluate the performance of driving pressure (DP)×respiratory rate (RR) to predict the outcome of weaning. Methods Plateau pressure (Pplat) and total positive end-expiratory pressure (PEEPtot) were measured during mechanical ventilation with brief deep sedation and on volume-controlled mechanical ventilation with a tidal volume of 6 mL/kg and a PEEP of 0 cmH2O. Pplat and PEEPtot were measured by patients holding their breath for 2 s after inhalation and exhalation, respectively. DP was determined as Pplat minus PEEPtot. The rapid shallow breathing index was measured from the ventilator. The highest RR was recorded within 3 minutes during a spontaneous breathing trial. Patients who tolerated a spontaneous breathing trial for 1 hour were extubated. Results Among the 105 patients studied, 44 failed weaning. During ventilation withdrawal, DP×RR was 136.7±35.2 cmH2O breaths/minute in the success group and 230.2±52.2 cmH2O breaths/minute in the failure group. A DP×RR index >170.8 cmH2O breaths/minute had a sensitivity of 93.2% and specificity of 88.5% to predict failure of weaning. Conclusions Measurement of DP×RR during withdrawal of ventilation may help predict the weaning outcome. A high DP×RR increases the likelihood of weaning failure. Statement: This manuscript was previously posted as a preprint on Research Square with the following link: https://www.researchsquare.com/article/rs-15065/v3 and DOI: 10.21203/rs.2.24506/v3


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