scholarly journals Vitamin D status in critically ill patients: the evidence is now bioavailable!

Critical Care ◽  
2014 ◽  
Vol 18 (4) ◽  
pp. 449 ◽  
Author(s):  
Gennaro De Pascale ◽  
Sadeq A Quraishi
Keyword(s):  
Vitamin D ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Vitamin D Status

scholarly journals Vitamin D status and overall and sepsis mortality in critically ill patients

Critical Care ◽  
2013 ◽  
Vol 17 (S2) ◽  
Author(s):  
P Zajic ◽  
C Schnedl ◽  
T Valentin ◽  
A Grisold ◽  
A Holl ◽  
...  
Keyword(s):  
Vitamin D ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Vitamin D Status ◽  
Sepsis Mortality

MON-PO611: Vitamin D Status and Inflammatory Bio-Markers in Critically Ill Patients with Sepsis

2019 ◽  
Vol 38 ◽  
pp. S285-S286
Author(s):  
L.S. Alnasrallah ◽  
M.M.A. Abulmeaty ◽  
A.M. Almajwal ◽  
Y. Arabi ◽  
H. Aldorzih ◽  
...  
Keyword(s):  
Vitamin D ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Vitamin D Status

scholarly journals Respond to Vitamin D status in adult critically ill patients in Eastern India: An observational retrospective study

Lung India ◽  
2015 ◽  
Vol 32 (2) ◽  
pp. 201
Author(s):  
Rajesh Padhi ◽  
Baikunthanath Panda ◽  
Snehalata Jagati ◽  
SubhasChandra Patra
Keyword(s):  
Vitamin D ◽  
Retrospective Study ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Vitamin D Status ◽  
Eastern India

scholarly journals Up to 40% of COVID-19 Critically Ill Patients Have Vitamin D Deficiency

2020 ◽  
Author(s):  
Teresa-Maria Tomasa-Irriguible ◽  
Lara Bielsa-Berrocal
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Statistical Significance ◽  
Vitamin D Status ◽  
Reactive Protein ◽  
Vitamin D Levels ◽  
Polymerase Chain ◽  
Potential Strategy

Background: Coronavirus disease (COVID-19) has caused more than 745,000 deaths worldwide. Vitamin D has been identified as a potential strategy to prevent or treat this disease. The purpose of the study was to measure vitamin D at hospital admission of COVID-19; Methods: We included critically ill patients with the polymerase chain reaction positive test for COVID-19, from March to April, 2020. Statistical significance was defined as P < .05. All tests were 2-tailed; Results: A total of 35 patients (median age, 60 years; 26 [74.3%] male) were included. Vitamin D levels were categorized as deficient for 14 participants (40%). Vitamin D deficiency was associated with vitamin A (P= 0.003) and Zinc (P= 0.019) deficiency and lower levels of albumin (P= 0.026) and prealbumin (P= 0.009). Overall, none of the studied variables were associated with vitamin D status: mortality, intensive care unit (ICU) or hospital stay, necessity of vasoactive agents, intubation, prone position, C reactive protein (CRP), Dimer-D, Interleukin 6 levels (IL-6), ferritin levels, or bacterial superinfection; Conclusions: In this single-center, retrospective cohort study, deficient vitamin D status was found in 40% in COVID-19 critically ill patients. However, deficient vitamin D status was not associated with inflammation or outcome.

scholarly journals Vitamin D status and its influence on outcomes following major burn injury and critical illness

2018 ◽  
Vol 6 ◽  
Author(s):  
Khaled Al-Tarrah ◽  
Martin Hewison ◽  
Naiem Moiemen ◽  
Janet M. Lord
Keyword(s):  
Vitamin D ◽  
Critical Illness ◽  
Vitamin D Deficiency ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Thermal Injury ◽  
Burn Injury ◽  
Vitamin D Supplementation ◽  
Burn Patients ◽  
Vitamin D Status

Abstract Vitamin D deficiency is common among the general population. It is also observed in up to 76% of critically ill patients. Despite the high prevalence of hypovitaminosis D in critical illness, vitamin D is often overlooked by medical staff as the clinical implications and consequences of vitamin D deficiency in acute contexts remain to be fully understood. Vitamin D has a broad range of pleotropic effects on various processes and systems including the immune-inflammatory response. 1α,25-dihydroxyvitamin D (1,25(OH)2D), has been shown to promote a tolerogenic immune response limiting deleterious inflammatory effects, modulation of the innate immune system, and enhancement of anti-microbial peptides. Vitamin D deficiency is frequently observed in critically ill patients and has been related to extrinsic causes (i.e., limited sunlight exposure), magnitude of injury/illness, or the treatment started by medical doctors including fluid resuscitation. Low levels of vitamin D in critically ill patients have been associated with sepsis, organ failure, and mortality. Despite this, there are subpopulations of critical illness, such as burn patients, where the literature regarding vitamin D status and its influence on outcomes remain insufficient. Thermal injury results in damage to both burned and non-burned tissues, as well as induces an exaggerated and persistent immune-inflammatory and hypermetabolic response. In this review, we propose potential mechanisms in which burn injury affects the vitamin D status and summarizes current literature investigating the influence of vitamin D status on outcomes. In addition, we reviewed the literature and trials investigating vitamin D supplementation in critically ill patients and discuss the therapeutic potential of vitamin D supplementation in burn and critically ill patients. We also highlight current limitations of studies that have investigated vitamin D status and supplementation in critical illness. Thermal injury influences vitamin D status. More studies investigating vitamin D depletion in burn patients and its influence on prognosis, via standardized methodology, are required to reach definitive conclusions and influence clinical practice.

scholarly journals Vitamin D status in critically ill patients: back to basics!

Critical Care ◽  
2014 ◽  
Vol 18 (6) ◽  
Author(s):  
Anne-Françoise Rousseau ◽  
Etienne Cavalier
Keyword(s):  
Vitamin D ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Vitamin D Status

scholarly journals Acute fluid shifts influence the assessment of serum vitamin D status in critically ill patients

Critical Care ◽  
2010 ◽  
Vol 14 (6) ◽  
pp. R216 ◽  
Author(s):  
Anand Krishnan ◽  
Judith Ochola ◽  
Julie Mundy ◽  
Mark Jones ◽  
Peter Kruger ◽  
...  
Keyword(s):  
Vitamin D ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Serum Vitamin ◽  
Vitamin D Status ◽  
Serum Vitamin D ◽  
Fluid Shifts

scholarly journals Impact of Hospital‐Acquired Infection on Vitamin D Status in Critically Ill Patients

2015 ◽  
Vol 29 (S1) ◽  
Author(s):  
B Peterson ◽  
J Alvarez ◽  
J Jones ◽  
G Hebbar ◽  
D Griffith ◽  
...  
Keyword(s):  
Vitamin D ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Vitamin D Status ◽  
Hospital Acquired Infection ◽  
Hospital Acquired
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