scholarly journals A new miniaturized extracorporeal membrane oxygenator with integrated rotary blood pump (Ilias): first results in a porcine model of lung injury

Critical Care ◽  
2012 ◽  
Vol 16 (S1) ◽  
Author(s):  
K Pilarczyk ◽  
J Heckmann ◽  
K Lyskawa ◽  
A Strauß ◽  
U Aschenbrenner ◽  
...  
ASAIO Journal ◽  
2011 ◽  
Vol 57 (3) ◽  
pp. 158-163 ◽  
Author(s):  
Ruedger Kopp ◽  
Ralf Bensberg ◽  
Jutta Arens ◽  
Ulrich Steinseifer ◽  
Thomas Schmitz-Rode ◽  
...  

Membranes ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 379
Author(s):  
Sung Yoon Lim ◽  
Young-Jae Cho ◽  
Dong Jung Kim ◽  
Jun Sung Kim ◽  
Sanghoon Jheon ◽  
...  

Low-tidal-volume ventilation decreases mortality in acute respiratory distress syndrome (ARDS) patients. This study investigated the effects of ultralow tidal ventilation under veno-venous extracorporeal membrane oxygenator (ECMO) support in pigs with ARDS. Eight pigs were intubated and inoculated with methicillin-resistant Staphylococcus aureus through bronchoscopy. Ultralow tidal ventilation (3 mL/kg) under extracorporeal membrane oxygenator (ECMO) support was applied to one group and high tidal ventilation (15 mL/kg) was applied to another group to maintain comparable oxygenation for 12 h without ECMO support. Each group had similar arterial blood gas values and hemodynamic variables at baseline and during the experiment. The high-tidal-volume ventilation group showed a gradual decline in arterial oxygen levels, and repeated ANOVA showed significant differences in oxygenation change over time in the ultralow tidal ventilation group. Inflammatory cytokine levels in the bronchoalveolar lavage fluid and lung ultrasound scores were similar between two groups. Histologic analysis showed that both groups developed pneumonia after 12 h; however, the ultralow tidal ventilation group had a lower lung injury score assessed by the pathologist. We developed the first ultralow-tidal-volume ventilation porcine model under veno-venous ECMO support. The ultralow-tidal-volume ventilation strategy can mitigate mechanical ventilator-associated lung injury.


2003 ◽  
Vol 27 (6) ◽  
pp. 530-536 ◽  
Author(s):  
Rolf Dembinski ◽  
Rudger Kopp ◽  
Dietrich Henzler ◽  
Nadine Hochhausen ◽  
Nicole Oslender ◽  
...  

2008 ◽  
Vol 56 (S 1) ◽  
Author(s):  
M Grossmann ◽  
J Landrath ◽  
I Merkel ◽  
R Holland ◽  
W Juettner ◽  
...  

Author(s):  
M. V. Denisov ◽  
M. Walter ◽  
S. Leonhard ◽  
D. V. Telyshev
Keyword(s):  

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