scholarly journals Selenium Levels and Glutathione Peroxidase Activity in Blood, Plasma and Reproductive Organs in Dairy Cows

1988 ◽  
Vol 29 (3-4) ◽  
pp. 431-435
Author(s):  
Erik Ropstad ◽  
Arne Frøslie ◽  
Kristina Landsverk
Keyword(s):  
Glutathione Peroxidase ◽  
Blood Plasma ◽  
Dairy Cows ◽  
Peroxidase Activity ◽  
Reproductive Organs ◽  
Glutathione Peroxidase Activity ◽  
In Blood Plasma

scholarly journals Effect of T-2 and HT-2 Toxin during the Growing Period on Body Weight, Lipid Peroxide and Glutathione Redox Status of Broiler Chickens

2010 ◽  
Vol 79 (1) ◽  
pp. 27-31 ◽  
Author(s):  
Mária Weber ◽  
Krisztián Balogh ◽  
Judit Fodor ◽  
Márta Erdélyi ◽  
Zsolt Ancsin ◽  
...  
Keyword(s):  
Body Weight ◽  
Glutathione Peroxidase ◽  
Blood Cell ◽  
Blood Plasma ◽  
Red Blood Cell ◽  
Peroxidase Activity ◽  
Broiler Chickens ◽  
Reduced Glutathione ◽  
Liver Homogenate ◽  
Glutathione Peroxidase Activity

The effect of T-2 and HT-2 toxin using different doses in the starter (0-21 days: 1.04 mg T-2 toxin and 0.49 mg HT-2 toxin kg-1feed), and finisher diets (22-39 days: 0.12 mg T-2 toxin and 0.02 mg HT-2 toxin kg-1feed) was investigated in broiler chickens. Birds were divided into two groups fed with control and T-2 and HT-2 toxin contaminated diets. Pathological signs of toxicity were investigated on days 21 and 39 of the trial, individual liveweight was measured weekly. Five birds from each group were sacrificed on the 21st and 39th days of treatment, when blood plasma, red blood cell, liver and kidney samples were taken, in which malondialdehyde and reduced glutathione concentration and glutathione-peroxidase activity were determined. Pathological signs (lesions in the oral cavity and on the tongue, inflammation in the small intestine) were found in the group fed T-2 and HT-2 toxin contaminated feed on day 21 compared to control. Body weight was significantly lower as a result of feeding T-2 and HT-2 toxin contaminated diet. However, the contamination did not cause a significant increase of malondialdehyde content in the analysed tissues. Reduced glutathione content was significantly lower in the liver homogenate on day 39 than that of the control. Glutathione peroxidase activity also did not differ significantly in blood plasma, red blood cell haemolysates and kidney homogenates, while it was significantly higher in the liver homogenates of the mycotoxin-challenged birds. In conclusion, it can be stated that T-2 and HT-2 toxin exposure has long-term effects in broiler chickens.

Effects of ochratoxin a on some production traits, lipid peroxide and glutathione redox status of weaned piglets

2007 ◽  
Vol 55 (4) ◽  
pp. 463-470 ◽  
Author(s):  
K. Balogh ◽  
J. Hausenblasz ◽  
Mária Weber ◽  
Márta Erdélyi ◽  
Judit Fodor ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Glutathione Peroxidase ◽  
Blood Plasma ◽  
Peroxidase Activity ◽  
Redox System ◽  
Production Traits ◽  
Weaned Piglets ◽  
Glutathione Peroxidase Activity ◽  
Glutathione Redox System ◽  
Glutathione Redox

The effect of feeding ochratoxin A (OTA) contaminated diet (379.6 and 338.1 μg/kg in starter and grower diets) on production traits, lipid peroxidation and some parameters of the glutathione redox system were investigated in weaned piglets over a seven-week period. Feed intake and feed conversion ratio (FCR) did not differ significantly, but in the first phase (0–28 days) the daily weight gain was significantly lower in the piglets fed the OTA-contaminated diet. Lipid peroxidation, as measured by the amount of malondialdehyde, glutathione content and glutathione peroxidase activity, did not change significantly in the blood plasma and red blood cell haemolysate in the OTA-loaded group, while malondialdehyde content increased significantly in the liver and markedly but not significantly in the kidney of piglets fed OTA-contaminated feed. Glutathione content did not differ significantly in the studied organs of the two groups while glutathione peroxidase activity of the OTA-loaded animals was significantly lower both in the liver and in the kidney. The results suggest that the use of feed-stuffs contaminated with low levels of OTA for seven weeks did not cause marked differences in the production traits or in lipid peroxidation and amount or activity of the glutathione redox system in the blood plasma, red blood cells and kidney, while significant changes occurred in the liver homogenate.

Selenium biofortified alfalfa hay fed in low quantities improves selenium status and glutathione peroxidase activity in transition dairy cows and their calves

2020 ◽  
Vol 87 (2) ◽  
pp. 184-190 ◽  
Author(s):  
Shana Jaaf ◽  
Brandon Batty ◽  
Angela Krueger ◽  
Charles T. Estill ◽  
Massimo Bionaz
Keyword(s):  
Glutathione Peroxidase ◽  
Dairy Cows ◽  
Peroxidase Activity ◽  
Post Partum ◽  
Selenium Status ◽  
Glutathione Peroxidase Activity ◽  
Dry Period ◽  
Alfalfa Hay ◽  
Gpx Activity ◽  
Modest Effect

AbstractThe hypothesis of the study was that feeding a relatively low amount of Se biofortified alfalfa hay during the dry period and early lactation would improve selenium status and glutathione peroxidase activity in dairy cows and their calves. Ten Jersey and 8 Holstein primiparous dairy cows were supplemented with Se biofortified (TRT; n = 9) or non-biofortified (CTR; n = 9) alfalfa hay at a rate of 1 kg/100 kg of BW mixed with the TMR from 40 d prior parturition to 2 weeks post-partum. Se concentration in whole blood, liver, milk, and colostrum, the transfer of Se to calves, and the glutathione peroxidase (GPx) activity were assessed. TRT had 2-fold larger (P < 0.05) Se in blood v. CTR that resulted in larger Se in liver and colostrum but not milk and larger GPx activity in plasma and erythrocytes but not in milk. Compared to CTR, calves from TRT had larger Se in blood but only a numerical (P = 0.09) larger GPx activity in plasma. A positive correlation was detected between Se in the blood and GPx activity in erythrocytes and plasma in cows. Our results demonstrated that feeding pregnant primiparous dairy cows with a relatively low amount of Se-biofortified alfalfa hay is an effective way to increase Se in the blood and liver, leading to greater antioxidant activity via GPx. The same treatment was effective in improving Se concentration in calves but had a modest effect on their GPx activity. Feeding Se biofortified hay increased Se concentration in colostrum but not in milk.

Low Selenium Status in the Elderly Influences Thyroid Hormones

1995 ◽  
Vol 89 (6) ◽  
pp. 637-642 ◽  
Author(s):  
Oliviero Olivieri ◽  
Domenico Girelli ◽  
Margherita Azzini ◽  
Anna Maria Stanzial ◽  
Carla Russo ◽  
...  
Keyword(s):  
Glutathione Peroxidase ◽  
Thyroid Hormones ◽  
Peroxidase Activity ◽  
Controlled Trial ◽  
The Elderly ◽  
Serum Selenium ◽  
Selenium Status ◽  
Glutathione Peroxidase Activity ◽  
Double Blind ◽  
Double Blind Placebo

1. Iodothyronine 5′-deiodinase, which is mainly responsible for peripheral triiodothyronine (T3) production, has recently been demonstrated to be a selenium-containing enzyme. In the elderly, reduced peripheral conversion of thyroxine (T4) to T3 and overt hypothyroidism are frequently observed. 2. We measured serum selenium and erythrocyte glutathione peroxidase (as indices of selenium status), thyroid hormones and thyroid-stimulating hormone in 109 healthy euthyroid subjects (52 women, 57 men), carefully selected to exclude abnormally low thyroid hormone levels induced by acute or chronic diseases or calorie restriction. The subjects were subdivided into three age groups. To avoid conditions of undernutrition or malnutrition, dietary records were obtained for a sample of 24 subjects, randomly selected and representative of the whole population for age and sex. 3. In order to properly assess the influence of selenium status on iodothyronine 5′-deiodinase type I activity, a double-blind placebo-controlled trial was also carried out on 36 elderly subjects, resident at a privately owned nursing home. 4. In the free-living population, a progressive reduction of the T3/T4 ratio (due to increased T4 levels) and of selenium and erythrocyte glutathione peroxidase activity was observed with advancing age. A highly significant linear correlation between T4, T3/T4 and selenium was observed in the population as a whole (for T4, R = −0.312, P < 0.002; for T3/T4 ratio, R = 0.32, P < 0.01) and in older subjects (for T4, R = −0.40, P < 0.05; for T3/T4 ratio, R = 0.54, P < 0.002). 5. The main result of the double-blind placebo-controlled trial was a significant improvement of selenium indices and a decrease in the T4 level in selenium-treated subjects; serum selenium, erythrocyte glutathione peroxidase activity and thyroid hormones did not change in placebo-treated subjects. 6. We concluded that selenium status influences thyroid hormones in the elderly, mainly modulating T4 levels.

Sign in / Sign up

Export Citation Format

Share Document