scholarly journals Ovine White-Liver Disease (OWLD). Vitamin B12 and Methyl Malonic Acid (MMA) Estimations in Blood

1990 ◽  
Vol 31 (3) ◽  
pp. 267-275
Author(s):  
Martha J. Ulvund
Keyword(s):  
Liver Disease ◽  
Vitamin B12 ◽  
Malonic Acid

Vitamin B12 and hepatic enzyme serum levels correlate with interleukin-6 in alcohol-dependent individuals without liver disease

2007 ◽  
Vol 40 (11) ◽  
pp. 781-786 ◽  
Author(s):  
Ioannis A. Liappas ◽  
Chryssoula Nicolaou ◽  
Stylianos Chatzipanagiotou ◽  
Elias O. Tzavellas ◽  
Christina Piperi ◽  
...  
Keyword(s):  
Liver Disease ◽  
Vitamin B12 ◽  
Interleukin 6 ◽  
Serum Levels ◽  
Hepatic Enzyme ◽  
Alcohol Dependent

Vitamin B12 Excretion as Index of Hepatic Disorders

1958 ◽  
Vol 4 (1) ◽  
pp. 27-31 ◽  
Author(s):  
Herman Baker ◽  
G Brill ◽  
I Pasher ◽  
Harry Sabotka
Keyword(s):  
Heart Disease ◽  
Liver Disease ◽  
Vitamin B12 ◽  
Rheumatic Heart Disease ◽  
Intramuscular Injection ◽  
Protein Composition ◽  
Hepatic Disease ◽  
Binding Factor ◽  
The Subject ◽  
Rheumatic Heart

Abstract Observations on lowered excretion of vitamin B12 after intramuscular injection of 60 µg. of this vitamin in hepatic disease have been extended and confirmed. Except for some borderline cases in other diseases with possible involvement of the liver, we find low excretion in rheumatic heart disease as well as in lobar pneumonia, previously reported. The mechanism underlying the deviations from the normal situation in liver disease and rheumatic heart disease in respect to the vitamin B12 binding factor, to the serum protein composition, and the role played by the kidney is the subject of current studies.

Hepatic and Serum Vitamin B12 Content in Liver Disease

1960 ◽  
Vol 38 (2) ◽  
pp. 188-193 ◽  
Author(s):  
Robert S. Nelson ◽  
Vasant M. Doctor
Keyword(s):  
Liver Disease ◽  
Vitamin B12 ◽  
Serum Vitamin

Cobalamin (Vitamin B12) and Holotranscobalamin Changes in Plasma and Liver Tissue in Alcoholics with Liver Disease

1998 ◽  
Vol 17 (3) ◽  
pp. 235-238 ◽  
Author(s):  
Herman Baker ◽  
Carroll B. Leevy ◽  
Barbara DeAngelis ◽  
Oscar Frank ◽  
Elliott R. Baker
Keyword(s):  
Liver Disease ◽  
Vitamin B12 ◽  
Liver Tissue

The Blood Vitamin B12 Level in Liver Disease

2009 ◽  
Vol 163 (6) ◽  
pp. 515-523
Author(s):  
H. P. ØSTERGAARD KRISTENSEN
Keyword(s):  
Liver Disease ◽  
Vitamin B12

Vitamin B12 and Methyl Malonic Acid: Do We Have All the Answers?

2003 ◽  
Vol 51 (2) ◽  
pp. 279-280 ◽  
Author(s):  
Giridhar U. Adiga ◽  
Thiruvinvamalai S. Dharmarajan
Keyword(s):  
Vitamin B12 ◽  
Malonic Acid

scholarly journals VITAMIN B12 AND HOMOCYSTEINE LEVELS IN PATIENTS WITH NAFLD: A SYSTEMATIC REVIEW AND METANALYSIS

2021 ◽  
Author(s):  
Débora Silva COSTA ◽  
Marina P GUAHNON ◽  
Fernanda Braga SEGANFREDO ◽  
Letícia P PINTO ◽  
Cristiane V TOVO ◽  
...  
Keyword(s):  
Systematic Review ◽  
Liver Disease ◽  
Vitamin B12 ◽  
Liver Damage ◽  
Fatty Liver Disease ◽  
Serum Vitamin ◽  
Nonalcoholic Fatty Liver ◽  
Potential Marker ◽  
Vitamin B12 Absorption ◽  
Low Serum

ABSTRACT BACKGROUND: The vitamin B12 absorption can be affected in patients with nonalcoholic fatty liver disease (NAFLD), and low serum vitamin B12 levels has been related to the high homocysteine (HCY) levels and to the degree of NAFLD. OBJECTIVE: To carry out a systematic review and metanalysis of serum vitamin B12 and HCY levels in patients with NAFLD. METHODS: Original studies including serum vitamin B12 and HCY levels in humans with NAFLD were included. The searches were performed in four databases. RESULTS: 159 studies were identified, and after excluding the duplicates and non-eligible titles, eight original articles were included. Six out of eight showed higher B12 levels in NAFLD patients (404.9±136.2 pg/mL in relation to controls 353.91±117.3 pg/mL). Seven of the eight studies also showed higher HCY levels in NAFLD patients (14.2±3.44 umol/L in relation to controls 11.05±3.6 umol/L). The results for serum vitamin B12 and HCY levels were submitted to metanalysis, showing no difference in the vitamin B12 levels between patients with NAFLD and controls. However, the levels of Hcy were higher in NAFLD patients than in controls. CONCLUSION: There was no relashionship between the vitamin B12 levels and NAFLD. The levels of HCY were significantly higher in patients with NAFLD, suggesting this could be a potential marker for liver damage.

scholarly journals The effect of antibiotics on rats receiving a vitamin B12-deficient diet

1970 ◽  
Vol 24 (2) ◽  
pp. 405-412 ◽  
Author(s):  
D. L. Williams ◽  
G. H. Spray
Keyword(s):  
Urinary Excretion ◽  
Vitamin B12 ◽  
Malonic Acid ◽  
Methylmalonic Acid ◽  
Deficient Diet

1. Rats fed on a vitamin B12-deficient or -supplemented diet were given either neomycin or a mixture of streptomycin and erythromycin by mouth for between 7 and 15 d. The urinary excretion of methylmalonic acid and the levels of vitamin B12 in plasma and tissues and of acetic and propionic acids in caecal contents were measured.2. Both treatments caused prompt reduction of methylmalonate excretion in the deficient rats. This was apparently due to depression of the production of some precursor of methyl-malonic acid, probably propionate, rather than to an immediate effect on vitamin B12 nutrition.3. After withdrawal of the antibiotics, neomycin-treated vitamin B12-deficient rats appeared to become partly repleted in vitamin B12, but the change in the vitamin B12 status of those which had received streptomycin and erythromycin was much smaller.

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