scholarly journals The Distribution of Soluble Copper- and Zinc-Binding Proteins in Liver and Kidney of Chronic Copper-Poisoned Goats

1980 ◽  
Vol 21 (4) ◽  
pp. 578-586
Author(s):  
Milica Mjør-Grimsrud ◽  
Nils E. Søli ◽  
Gunnar Norheim
Keyword(s):  
Binding Proteins ◽  
Zinc Binding ◽  
Copper And Zinc ◽  
Liver And Kidney

Copper- and Zinc-binding Proteins in Sheep Liver and Intestine: Effects of Dietary Levels of the Metals

1980 ◽  
Vol 110 (3) ◽  
pp. 460-468 ◽  
Author(s):  
William W. Saylor ◽  
Franklin D. Morrow ◽  
Roland M. Leach
Keyword(s):  
Binding Proteins ◽  
Zinc Binding ◽  
Sheep Liver ◽  
Copper And Zinc

scholarly journals Hepatic copper–and zinc-binding proteins in ruminants

1974 ◽  
Vol 32 (2) ◽  
pp. 283-291 ◽  
Author(s):  
I Bremner ◽  
R. B Marshall
Keyword(s):  
Molecular Weight ◽  
Metal Binding ◽  
Binding Proteins ◽  
Mutual Interaction ◽  
Zinc Binding ◽  
Direct Function ◽  
Hepatic Copper ◽  
Copper And Zinc ◽  
Zn Concentration ◽  
Cu And Zn

1. A metal-binding fraction with a molecular weight of about 12000 in calf and sheep liver has been characterized as a metallothionein-like protein.2. The combined concentrations of copper and zinc in the fraction (as μg/g liver) are a direct function of liver Zn concentration.3. The relative proportions of Cu and Zn in the fraction are dependent on the Cu: Zn ratio in the liver.4. These findings may be relevant to the mutual interaction between Cu and Zn.

scholarly journals Isolation of (copper, zinc)-thioneins from the livers of copper-injected rats

1976 ◽  
Vol 157 (2) ◽  
pp. 517-520 ◽  
Author(s):  
I Bremner ◽  
B W Young
Keyword(s):  
Rat Liver ◽  
Metal Atom ◽  
Binding Proteins ◽  
Zinc Binding ◽  
Cysteine Residues ◽  
Copper And Zinc ◽  
Total Metal ◽  
Copper Zinc

The mixed copper- and zinc-binding proteins, with mol.wt. of approx. 12000, induced in rat liver after injection of copper were isolated and characterized as metallothioneins. Three separate forms were obtained, with 7-11% total metal in the protein, equivalent to 2.6-1.6 cysteine residues/metal atom.

The Distribution of Soluble Copper- and Zinc-binding Proteins in Goat Liver

2009 ◽  
Vol 44 (5) ◽  
pp. 319-323 ◽  
Author(s):  
Milica Mjör-Grimsrud ◽  
Nils E. Søli ◽  
Tore Sivertsen
Keyword(s):  
Binding Proteins ◽  
Zinc Binding ◽  
Copper And Zinc

scholarly journals Fractionation of Soluble Copper- and Zinc-Binding Proteins From Cattle Liver

1980 ◽  
Vol 21 (1) ◽  
pp. 71-78 ◽  
Author(s):  
Milica Mjør-Grimsrud ◽  
Gunnar Norheim
Keyword(s):  
Binding Proteins ◽  
Zinc Binding ◽  
Copper And Zinc

scholarly journals Hepatic copper–and zinc-binding proteins in ruminants

1974 ◽  
Vol 32 (2) ◽  
pp. 293-300 ◽  
Author(s):  
I Bremner ◽  
R. B Marshall
Keyword(s):  
Molecular Weight ◽  
Binding Proteins ◽  
Gel Filtration ◽  
Weight Fraction ◽  
Zinc Binding ◽  
Molecular Weights ◽  
Hepatic Copper ◽  
Copper And Zinc ◽  
Zn Status ◽  
Cu And Zn

1. A study has been made by gel-filtration techniques of the soluble copper- and zinc-binding proteins in livers from calves and sheep of widely differing Cu and Zn status.2. Cu and Zn generally occurred together in three main fractions, with approximate molecular weights of > 75000, 35000 and 12000, and Zn also in one other fraction with molecular weight about 65000. The distribution of the metals between these fractions was variable and dependent on both the Cu and Zn status of the animals.3. Zn was usually absent from the low-molecular-weight fraction in Zn-deficient or high-Cu livers, with Cu also being absent in the former instance.4. The fraction with molecular weight of 35000 was tentatively identified as hepatocuprein. It generally accounted for only 4% of the total hepatic Cu except in Cu-deficient livers.5. The possible relationship of these findings to the mutual antagonism between Cu and Zn is discussed.

scholarly journals Proteins of the canine seminal plasma

2016 ◽  
Vol 46 (5) ◽  
pp. 901-908 ◽  
Author(s):  
Annice Aquino-Cortez ◽  
Lúcia Daniel Machado da Silva ◽  
Airton Alencar de Araújo ◽  
Erika da Silva Bezerra de Menezes ◽  
Arlindo de Alencar Araripe Noronha Moura
Keyword(s):  
Alkaline Phosphatase ◽  
Seminal Plasma ◽  
Binding Proteins ◽  
Reproductive Tract ◽  
Sperm Quality ◽  
Zinc Binding ◽  
Heparin Binding ◽  
Reproductive Disorders ◽  
The Matrix ◽  
Peroxidase Enzymes

ABSTRACT: Studies have been performed to identify the proteins present in canine seminal plasma (SP) and relate them to sperm quality as well as to discover molecular markers of reproductive tract diseases. There is evidence that heparin-binding proteins, zinc-binding proteins, and lactoferrin as well as the matrix metalloproteinase, superoxide dismutase, catalase, and glutathione peroxidase enzymes are associated with canine sperm quality. Other studies indicate that prolactin and enzymes like arginine esterase, acid phosphatase, and alkaline phosphatase could be successfully used as biomarkers of reproductive disorders. Thus, the present literature review aims to address aspects related to proteins of the canine SP, their influence on fertility, and their importance as biomarkers of reproductive disorders.

Zinc- and copper-binding proteins in the plasma of winter flounder (Pseudopleuronectes americanus)

1980 ◽  
Vol 58 (4) ◽  
pp. 609-613 ◽  
Author(s):  
P. E. Fletcher ◽  
G. L. Fletcher
Keyword(s):  
Molecular Weight ◽  
Binding Proteins ◽  
Binding Protein ◽  
Gel Filtration ◽  
Protein S ◽  
Egg Yolk ◽  
Winter Flounder ◽  
Zinc Binding ◽  
Copper Binding ◽  
Copper Binding Proteins

Zinc- and copper-binding proteins were isolated from the plasma of winter flounder using gel filtration chromatography. A single copper-binding protein fraction of molecular weight 170 000 was isolated from the plasma of both sexes.In male and female flounder over 95% of the plasma zinc was associated with a zinc-binding protein(s) with a molecular weight of 76 000. In male flounder the remaining zinc appeared to be bound to a protein(s) of molecular weight 186 000. In female flounder the remaining 5% of the zinc was associated with two zinc-binding fractions with apparent molecular weights of 186 000 and 340 000 – 370 000.Extracts of plasma vitellogenin and egg yolk proteins revealed significant quantities of zinc and copper. It is hypothesized that the female specific zinc-binding protein (340 000 – 370 000) was vitellogenin.

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