scholarly journals Accuracy of axillary nodal ultrasound and ultrasound fine needle aspiration/core biopsy in the preoperative staging of patients with invasive breast cancer

2015 ◽  
Vol 17 (S1) ◽  
Author(s):  
William Cheung ◽  
Suzanne McLenachan ◽  
Gauripriya Babu ◽  
Melanie Smith
Keyword(s):  
Breast Cancer ◽  
Invasive Breast Cancer ◽  
Fine Needle Aspiration ◽  
Core Biopsy ◽  
Preoperative Staging ◽  
Needle Aspiration ◽  
Fine Needle ◽  
Aspiration Core

scholarly journals Axillary ultrasound and fine-needle aspiration in preoperative staging of axillary lymph nodes in patients with invasive breast cancer

2015 ◽  
Vol 48 (6) ◽  
pp. 345-352 ◽  
Author(s):  
Rafael Dahmer Rocha ◽  
André Ricardo Girardi ◽  
Renata Reis Pinto ◽  
Viviane Aguilera Rolim de Freitas
Keyword(s):  
Breast Cancer ◽  
Lymph Nodes ◽  
Invasive Breast Cancer ◽  
Fine Needle Aspiration ◽  
Predictive Value ◽  
Preoperative Staging ◽  
Needle Aspiration ◽  
Axillary Lymph ◽  
Fine Needle ◽  
Definitive Therapy

Abstract Objective: To propose an algorithm to determine the necessity for ultrasonography-guided fine-needle aspiration (US-FNA) in preoperative axillary lymph node staging of patients with invasive breast cancer. Materials and Methods: Prospective study developed at National Cancer Institute. The study sample included 100 female patients with breast cancer referred for axillary staging by US-FNA. Results: The overall US-FNA sensitivity was set at 79.4%. The positive predictive value was calculated to be 100%, and the negative predictive value, 69.5%. The US-FNA sensitivity for lymph nodes with normal sonographic features was 0%, while for indeterminate lymph nodes it was 80% and, for suspicious lymph nodes, 90.5%. In the assessment of invasive breast tumors stages T1, T2 and T3, the sensitivity was respectively 69.6%, 83.7% and 100%. US-FNA could avoid sentinel node biopsy in 54% of cases. Conclusion: Axillary ultrasonography should be included in the preoperative staging of all patients with invasive breast cancer. The addition of US-FNA in cases of lymph nodes suspicious for malignancy may prevent more than 50% of sentinel lymphadenectomies, significantly shortening the time interval to definitive therapy.

scholarly journals Ultrasound Guided Core Biopsy versus Fine Needle Aspiration for Evaluation of Axillary Lymphadenopathy in Patients with Breast Cancer

ISRN Oncology ◽  
2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Marie A. Ganott ◽  
Margarita L. Zuley ◽  
Gordon S. Abrams ◽  
Amy H. Lu ◽  
Amy E. Kelly ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Fine Needle Aspiration ◽  
Core Biopsy ◽  
Needle Aspiration ◽  
Axillary Node ◽  
Axillary Lymph ◽  
Ultrasound Guided ◽  
Axillary Lymph Node Metastases ◽  
Fine Needle ◽  
Node Metastases

Rationale and Objectives. To compare the sensitivities of ultrasound guided core biopsy and fine needle aspiration (FNA) for detection of axillary lymph node metastases in patients with a current diagnosis of ipsilateral breast cancer. Materials and Methods. From December 2008 to December 2010, 105 patients with breast cancer and abnormal appearing lymph nodes in the ipsilateral axilla consented to undergo FNA of an axillary node immediately followed by core biopsy of the same node, both with ultrasound guidance. Experienced pathologists evaluated the aspirate cytology without knowledge of the core histology. Cytology and core biopsy results were compared to sentinel node excision or axillary dissection pathology. Sensitivities were compared using McNemar’s test. Results. Of 70 patients with axillary node metastases, FNA was positive in 55/70 (78.6%) and core was positive in 61/70 (87.1%) (P = 0.18). The FNA and core results were discordant in 14/70 (20%) patients. Ten cases were FNA negative/core positive. Four cases were FNA positive/core negative. Conclusion. Core biopsy detected six (8.6%) more cases of metastatic lymphadenopathy than FNA but the difference in sensitivities was not statistically significant. Core biopsy should be considered if the node is clearly imaged and readily accessible. FNA is a good alternative when a smaller needle is desired due to node location or other patient factors. This trial is registered with NCT01920139.

scholarly journals Cost Modeling of Preoperative Axillary Ultrasound and Fine-Needle Aspiration to Guide Surgery for Invasive Breast Cancer

2010 ◽  
Vol 17 (4) ◽  
pp. 953-958 ◽  
Author(s):  
Judy C. Boughey ◽  
James P. Moriarty ◽  
Amy C. Degnim ◽  
Melissa S. Gregg ◽  
Jason S. Egginton ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Invasive Breast Cancer ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Cost Modeling ◽  
Axillary Ultrasound ◽  
Fine Needle

DIAGNOSIS OF BREAST CANCER WITH CORE-BIOPSY AND FINE NEEDLE ASPIRATION CYTOLOGY

1996 ◽  
Vol 66 (9) ◽  
pp. 592-594 ◽  
Author(s):  
G. H. Poole ◽  
P. C. Willsher ◽  
S. E. Pinder ◽  
J. F. R. Robertson ◽  
C. W. Elston ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Core Biopsy ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology
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