scholarly journals Rare key functional domain missense substitutions in MRE11A, RAD50, and NBNcontribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study

2014 ◽  
Vol 16 (3) ◽  
Author(s):  
Francesca Damiola ◽  
Maroulio Pertesi ◽  
Javier Oliver ◽  
Florence Le Calvez-Kelm ◽  
Catherine Voegele ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Susceptibility ◽  
Mutation Screening ◽  
Breast Cancer Susceptibility ◽  
Case Control ◽  
Functional Domain ◽  
Breast Cancer Family ◽  
Cancer Family ◽  
Screening Study

ATM in breast cancer susceptibility: results of a pooled analysis of case-control mutation screening data

2008 ◽  
Vol 6 (9) ◽  
pp. 203
Author(s):  
D. Babikyan ◽  
F. Lesueur ◽  
C. Voegele ◽  
M. Vallee ◽  
F. Le Calvez-Kelm ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Susceptibility ◽  
Mutation Screening ◽  
Breast Cancer Susceptibility ◽  
Pooled Analysis ◽  
Case Control

scholarly journals RAD51 and Breast Cancer Susceptibility: No Evidence for Rare Variant Association in the Breast Cancer Family Registry Study

PLoS ONE ◽  
2012 ◽  
Vol 7 (12) ◽  
pp. e52374 ◽  
Author(s):  
Florence Le Calvez-Kelm ◽  
Javier Oliver ◽  
Francesca Damiola ◽  
Nathalie Forey ◽  
Nivonirina Robinot ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Rare Variant ◽  
Cancer Susceptibility ◽  
Breast Cancer Susceptibility ◽  
Registry Study ◽  
Breast Cancer Family ◽  
Rare Variant Association ◽  
Cancer Family

scholarly journals ABRAXAS (FAM175A) and Breast Cancer Susceptibility: No Evidence of Association in the Breast Cancer Family Registry

PLoS ONE ◽  
2016 ◽  
Vol 11 (6) ◽  
pp. e0156820 ◽  
Author(s):  
Anne-Laure Renault ◽  
Fabienne Lesueur ◽  
Yan Coulombe ◽  
Stéphane Gobeil ◽  
Penny Soucy ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Susceptibility ◽  
Breast Cancer Susceptibility ◽  
Breast Cancer Family ◽  
Cancer Family

scholarly journals Metabolomic profiles in breast cancer:a pilot case-control study in the breast cancer family registry

BMC Cancer ◽  
2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Marcelle M. Dougan ◽  
Yuqing Li ◽  
Lisa W. Chu ◽  
Robert W. Haile ◽  
Alice S. Whittemore ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Breast Cancer Family ◽  
Cancer Family ◽  
Control Study

scholarly journals Single Nucleotide Polymorphism in hsa-mir-196a-2 and Breast Cancer Risk: A Case Control Study

2011 ◽  
Vol 14 (5) ◽  
pp. 417-421 ◽  
Author(s):  
Dominik J. Jedlinski ◽  
Plamena N. Gabrovska ◽  
Stephen R. Weinstein ◽  
Robert A. Smith ◽  
Lyn R. Griffiths
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Cancer Susceptibility ◽  
Breast Cancer Susceptibility ◽  
Case Control ◽  
Cancer Tissue ◽  
Transcriptional Level ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

microRNAs are small, non-coding RNAs that influence gene expression on a post-transcriptional level. They participate in diverse biological pathways and may act as either tumor suppressor genes or oncogenes. As they may have an effect on thousands of target mRNAs, single-nucleotide polymorphisms in microRNA genes might have major functional consequences, because the microRNA's properties and/or maturation may change. miR-196a has been reported to be aberrantly expressed in breast cancer tissue. Additionally, the SNP rs11614913 in hsa-mir-196a-2 has been found to be associated with breast cancer risk in some studies although not in others. This study evaluated the association between rs11614913 and breast cancer risk in a Caucasian case-control cohort in Queensland, Australia. Results do not support an association of the tested hsa-mir-196a-2 polymorphism with breast cancer susceptibility in this cohort. As there is a discrepancy between our results and previous findings, it is important to assess the role of rs11614913 in breast cancer by further larger studies investigating different ethnic groups.

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