scholarly journals A population-based study of tumor gene expression and risk of breast cancer death among lymph node-negative patients

2006 ◽  
Vol 8 (3) ◽  
Author(s):  
Laurel A Habel ◽  
Steven Shak ◽  
Marlena K Jacobs ◽  
Angela Capra ◽  
Claire Alexander ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Lymph Node ◽  
Population Based ◽  
Cancer Death ◽  
Population Based Study ◽  
Node Negative ◽  
Breast Cancer Death ◽  
Tumor Gene Expression ◽  
Tumor Gene

scholarly journals In modern times, how important are breast cancer stage, grade and receptor subtype for survival: a population-based cohort study

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Anna L. V. Johansson ◽  
Cassia B. Trewin ◽  
Irma Fredriksson ◽  
Kristin V. Reinertsen ◽  
Hege Russnes ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Tumour Size ◽  
Breast Cancer Mortality ◽  
Population Based ◽  
Breast Cancer Treatment ◽  
Nodal Status ◽  
Cancer Death ◽  
Node Negative ◽  
Breast Cancer Death ◽  
Grade Tumour

Abstract Background In breast cancer, immunohistochemistry (IHC) subtypes, together with grade and stage, are well-known independent predictors of breast cancer death. Given the immense changes in breast cancer treatment and survival over time, we used recent population-based data to test the combined influence of IHC subtypes, grade and stage on breast cancer death. Methods We identified 24,137 women with invasive breast cancer aged 20 to 74 between 2005 and 2015 in the database of the Cancer Registry of Norway. Kaplan-Meier curves, mortality rates and adjusted hazard ratios for breast cancer death were estimated by IHC subtypes, grade, tumour size and nodal status during 13 years of follow-up. Results Within all IHC subtypes, grade, tumour size and nodal status were independent predictors of breast cancer death. When combining all prognostic factors, the risk of death was 20- to 40-fold higher in the worst groups compared to the group with the smallest size, low grade and ER+PR+HER2− status. Among node-negative ER+HER2− tumours, larger size conferred a significantly increased breast cancer mortality. ER+PR−HER2− tumours of high grade and advanced stage showed particularly high breast cancer mortality similar to TNBC. When examining early versus late mortality, grade, size and nodal status explained most of the late (> 5 years) mortality among ER+ subtypes. Conclusions There is a wide range of risks of dying from breast cancer, also across small breast tumours of low/intermediate grade, and among node-negative tumours. Thus, even with modern breast cancer treatment, stage, grade and molecular subtype (reflected by IHC subtypes) matter for prognosis.

scholarly journals HOXB13:IL17BR and molecular grade index and risk of breast cancer death among patients with lymph node-negative invasive disease

2013 ◽  
Vol 15 (2) ◽  
Author(s):  
Laurel A Habel ◽  
Lori C Sakoda ◽  
Ninah Achacoso ◽  
Xiao-Jun Ma ◽  
Mark G Erlander ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Invasive Disease ◽  
Cancer Death ◽  
Node Negative ◽  
Breast Cancer Death ◽  
Grade Index

scholarly journals A population-based study of the impact of the St-Gallen treatment guidelines on survival of women with node-negative breast cancer

The Breast ◽  
2003 ◽  
Vol 12 ◽  
pp. S17-S18
Author(s):  
N. Hebert-Croteau ◽  
J. Brisson ◽  
J. Latreille ◽  
M. Rivard ◽  
G. Martin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Treatment Guidelines ◽  
Population Based ◽  
Population Based Study ◽  
Node Negative ◽  
Node Negative Breast Cancer ◽  
The Impact

scholarly journals Radiogenomic Analysis of Breast Cancer by Linking MRI Phenotypes with Tumor Gene Expression

Radiology ◽  
2020 ◽  
Vol 296 (2) ◽  
pp. 277-287 ◽  
Author(s):  
Tycho Bismeijer ◽  
Bas H. M. van der Velden ◽  
Sander Canisius ◽  
Esther H. Lips ◽  
Claudette E. Loo ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Tumor Gene Expression ◽  
Tumor Gene

scholarly journals Cyclin E1 is a strong prognostic marker for death from lymph node negative breast cancer. A population-based case-control study

2015 ◽  
Vol 54 (4) ◽  
pp. 543-549 ◽  
Author(s):  
Claudia Lundgren ◽  
Cecilia Ahlin ◽  
Lars Holmberg ◽  
Rose-Marie Amini ◽  
Marie-Louise Fjällskog ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Prognostic Marker ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Node Negative ◽  
Cyclin E1 ◽  
Node Negative Breast Cancer ◽  
Control Study

scholarly journals Population-based study of the effect of gene expression profiling on adjuvant chemotherapy use in breast cancer patients under the age of 65 years

Cancer ◽  
2015 ◽  
Vol 121 (22) ◽  
pp. 4062-4070 ◽  
Author(s):  
Arnold L. Potosky ◽  
Suzanne C. O'Neill ◽  
Claudine Isaacs ◽  
Huei-Ting Tsai ◽  
Calvin Chao ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Adjuvant Chemotherapy ◽  
Gene Expression Profiling ◽  
Cancer Patients ◽  
Expression Profiling ◽  
Population Based ◽  
Breast Cancer Patients ◽  
Population Based Study
Sign in / Sign up

Export Citation Format

Share Document