scholarly journals Chromosomal imbalances mapped by array-based comparative genomic hybridization in an integrated approach to combat breast cancer in Denmark

2005 ◽  
Vol 7 (S2) ◽  
Author(s):  
J Li ◽  
X Zhang ◽  
TD Jensen ◽  
K Wang ◽  
S Kølvraa ◽  
...  
2005 ◽  
Vol 53 (3) ◽  
pp. 381-384 ◽  
Author(s):  
H. Tönnies ◽  
A. Gerlach ◽  
R. Klunker ◽  
R. Schultka ◽  
L. Göbbel

We present the first data on our comparative genomic hybridization (CGH)–based strategy for the analysis of ancient DNA (aDNA) samples extracted from fetuses preserved in the Meckel Anatomical Collection in Halle, Germany. The collection contains numerous differently fixed ancient samples of fetal malformations collected from the middle of the 18th to the early 19th century. The main objective of this study is to establish a “standard” aDNA extraction and amplification protocol as a prerequisite for successful CGH analyses to detect or exclude chromosomal imbalances possibly causative for the malformations described for the fetuses.


2002 ◽  
Vol 134 (1) ◽  
pp. 71-76 ◽  
Author(s):  
Xiao-Lu Yin ◽  
Angela Bik-Yu Hui ◽  
Jesse Chung-Sean Pang ◽  
Wai Sang Poon ◽  
Ho-Keung Ng

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