scholarly journals Lymph node metastases display gene expression profiles of their primary breast carcinomas

2005 ◽  
Vol 7 (S2) ◽  
Author(s):  
B Weigelt ◽  
LFA Wessels ◽  
AJ Bosma ◽  
AM Glas ◽  
DSA Nuyten ◽  
...  
Keyword(s):  
Gene Expression ◽  
Lymph Node ◽  
Lymph Node Metastases ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Breast Carcinomas ◽  
Node Metastases

scholarly journals Gene Expression of Mesenchyme Forkhead 1 (FOXC2) Significantly Correlates With the Degree of Lymph Node Metastasis in Colorectal Cancer

2011 ◽  
Vol 96 (3) ◽  
pp. 207-216 ◽  
Author(s):  
Toshiaki Watanabe ◽  
Takashi Kobunai ◽  
Yoko Yamamoto ◽  
Keiji Matsuda ◽  
Soichiro Ishihara ◽  
...  
Keyword(s):  
Gene Expression ◽  
Colorectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Lymph Node Metastases ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Node Metastasis ◽  
Node Metastases ◽  
Colorectal Cancer Patients

Abstract In stage III colorectal cancer, patients with N1 stage tumors show poorer outcome than patients with N2 stage tumors. Our objective was to identify genes that are predictive for the presence of lymph node metastasis, and to characterize the aggressiveness of lymph node metastases. Gene expression profiles of colorectal cancer were determined by microarray in training (n  =  116) and test (n  =  25) sets of patients. We identified 40 discriminating probes in patients with and without lymph node metastases. Using these probes, we could predict the presence of lymph node metastasis with an accuracy of 87.1% (training set) and 76.0% (test set). Among discriminating probes, FOXC2 expression was significantly correlated with the degree of lymph node metastasis. FOXC2 was expressed significantly and disparately in patients with N1 and N2 stage tumors as analyzed by real-time reverse transcriptase–polymerase chain reaction. FOXC2 appears to be involved in determining the aggressiveness of lymph node metastasis in colorectal cancer.

Gene expression profiles of primary breast tumors maintained in lymph node- and distant metastases

2004 ◽  
Vol 2 (3) ◽  
pp. 125
Author(s):  
B Weigelt ◽  
A.M Glas ◽  
L.F Wessels ◽  
A.T Witteveen ◽  
A.J Bosma ◽  
...  
Keyword(s):  
Gene Expression ◽  
Lymph Node ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Distant Metastases ◽  
Breast Tumors

PD.128 Gene expression profiles of oralsquamous cell carcinoma depending on lymph node status

2005 ◽  
Vol 1 (1) ◽  
pp. 104
Author(s):  
T. Fillies ◽  
H. Bürger ◽  
B. Brandt ◽  
D. Kemmmg ◽  
R. Werkmeister ◽  
...  
Keyword(s):  
Gene Expression ◽  
Lymph Node ◽  
Cell Carcinoma ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Lymph Node Status ◽  
Node Status

FAS and FAS-L expression by tumor cells and lymphocytes in breast carcinomas and their lymph node metastases

2005 ◽  
Vol 200 (11-12) ◽  
pp. 743-751 ◽  
Author(s):  
Harry L. Ioachim ◽  
Ramona Decuseara ◽  
Francesca Giancotti ◽  
Brent H. Dorsett
Keyword(s):  
Lymph Node ◽  
Tumor Cells ◽  
Lymph Node Metastases ◽  
Breast Carcinomas ◽  
Node Metastases ◽  
Fas L
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