scholarly journals Serum level of adiponectin is a surrogate independent biomarker of radiographic disease progression in early rheumatoid arthritis: results from the ESPOIR cohort

2013 ◽  
Vol 15 (6) ◽  
pp. R210 ◽  
Author(s):  
Magali Meyer ◽  
Jérémie Sellam ◽  
Soraya Fellahi ◽  
Salma Kotti ◽  
Jean-Philippe Bastard ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Serum Level ◽  
Disease Progression ◽  
Early Rheumatoid Arthritis ◽  
Radiographic Disease

scholarly journals Prediction of disease progression in early rheumatoid arthritis by ICTP, RF and CRP. A comparative 3-year follow-up study

Rheumatology ◽  
2000 ◽  
Vol 39 (9) ◽  
pp. 1009-1013 ◽  
Author(s):  
S. Aman ◽  
L. Paimela ◽  
M. Leirisalo-Repo ◽  
J. Risteli ◽  
H. Kautiainen ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Disease Progression ◽  
Early Rheumatoid Arthritis ◽  
Follow Up Study

scholarly journals EFFICACY OF ADALIMUMAB IN EARLY RHEUMATOID ARTHRITIS IN RELATION TO ITS SERUM LEVEL AND THE PRESENCE OF ANTI-DRUG ANTIBODY

2014 ◽  
pp. 624
Author(s):  
A. S. Avdeeva ◽  
E. N. Aleksandrova ◽  
D. E. Karateev ◽  
E. L. Luchikhina ◽  
A. A. Novikov ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Serum Level ◽  
Early Rheumatoid Arthritis

scholarly journals MHC class II expression on myeloid cells inversely correlates with disease progression in early rheumatoid arthritis

Rheumatology ◽  
2007 ◽  
Vol 46 (6) ◽  
pp. 931-933 ◽  
Author(s):  
R. B. Mueller ◽  
A. Skapenko ◽  
J. Wendler ◽  
F. Schuch ◽  
J. R. Kalden ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Disease Progression ◽  
Mhc Class Ii ◽  
Early Rheumatoid Arthritis ◽  
Myeloid Cells ◽  
Class Ii

scholarly journals Fc-gamma receptors and S100A8/A9 cause bone erosion during rheumatoid arthritis. Do they act as partners in crime?

Rheumatology ◽  
2019 ◽  
Vol 58 (8) ◽  
pp. 1331-1343 ◽  
Author(s):  
Irene Di Ceglie ◽  
Nik N L Kruisbergen ◽  
Martijn H J van den Bosch ◽  
Peter L E M van Lent
Keyword(s):  
Rheumatoid Arthritis ◽  
Immune System ◽  
Disease Progression ◽  
Immune Cells ◽  
Bone Erosion ◽  
Fcγ Receptor ◽  
Receptor Signalling ◽  
Radiographic Disease ◽  
Osteoclast Function ◽  
And Function

AbstractBone erosion is one of the central hallmarks of RA and is caused by excessive differentiation and activation of osteoclasts. Presence of autoantibodies in seropositive arthritis is associated with radiographic disease progression. ICs, formed by autoantibodies and their antigens, activate Fcγ-receptor signalling in immune cells, and as such stimulate inflammation-mediated bone erosion. Interestingly, ICs can also directly activate osteoclasts by binding to FcγRs on their surface. Next to autoantibodies, high levels of alarmins, among which is S100A8/A9, are typical for RA and they can further activate the immune system but also directly promote osteoclast function. Therefore, IC-activated FcγRs and S100A8/A9 might act as partners in crime to stimulate inflammation and osteoclasts differentiation and function, thereby stimulating bone erosion. This review discusses the separate roles of ICs, FcγRs and alarmins in bone erosion and sheds new light on the possible interplay between them, which could fuel bone erosion.

Does methotrexate affect serum level of IgA-alpha-1 antitrypsin complex in early rheumatoid arthritis?

1995 ◽  
Vol 14 (5) ◽  
pp. 566-569 ◽  
Author(s):  
J. K. Lacki ◽  
T. Schochat ◽  
K. Klama ◽  
S. H. Mackiewicz ◽  
W. Müller
Keyword(s):  
Rheumatoid Arthritis ◽  
Serum Level ◽  
Early Rheumatoid Arthritis ◽  
Alpha 1 Antitrypsin
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