scholarly journals High mixed venous oxygen saturation levels do not exclude fluid responsiveness in critically ill septic patients

Critical Care ◽  
10.1186/10326 ◽  
2011 ◽  
Vol 15 (4) ◽  
pp. R177 ◽  
Author(s):  
Dimitrios Velissaris ◽  
Charalampos Pierrakos ◽  
Sabino Scolletta ◽  
Daniel De Backer ◽  
Jean Vincent
1997 ◽  
Vol 6 (2) ◽  
pp. 132-140 ◽  
Author(s):  
P Lewis ◽  
E Nichols ◽  
G Mackey ◽  
A Fadol ◽  
L Sloane ◽  
...  

OBJECTIVE: To examine the effect of a change in body position (right or left lateral) and timing of backrub (immediate or delayed) on mixed venous oxygen saturation in surgical ICU patients. METHODS: A repeated-measures design was used to study 57 critically ill men. Mixed venous oxygen saturation was recorded at 1-minute intervals for 5 minutes in each of three periods: baseline, after turning, and after backrub. Subjects were randomly assigned to body position and timing of backrub. Subjects in the immediate-backrub group were turned and given a 1-minute backrub. Mixed venous oxygen saturation was measured at 1-minute intervals for 5 minutes at two points: after the backrub and then with the patient lying on his side. For subjects in the delayed-backrub group, saturation was measured at 1-minute intervals for 5 minutes at two different points: after the subject was turned to his side and after the backrub. RESULTS: Both position and timing of backrub had significant effects on mixed venous oxygen saturation across conditions over time. Subjects positioned on their left side had a significantly greater decrease in saturation when the backrub was started. At the end of the backrub, saturation was significantly lower in subjects lying on their left side than in subjects lying on their right side. The pattern of change differed according to the timing of the backrub, and return to baseline levels of saturation after intervention differed according to body position. CONCLUSIONS: Two consecutive interventions (change in body position and backrub) cause a greater decrease in mixed venous oxygen saturation than the two interventions separated by a 5-minute equilibration period. Turning to the left side decreases oxygen saturation more than turning to the ride side does. Oxygen saturation returns to clinically acceptable ranges within 5 minutes of an intervention. In patients with stable hemodynamic conditions, the standard practice of turning the patient and immediately giving a backrub is recommended. However, it is prudent to closely monitor individual patterns of mixed venous oxygen saturation, particularly in patients with unstable hemodynamic conditions.


1982 ◽  
Vol 61 (6) ◽  
pp. 513???517 ◽  
Author(s):  
Philippe L. Baele ◽  
John C. McMichan ◽  
H. Michael Marsh ◽  
J. Christopher Sill ◽  
Peter A. Southorn

Respiration ◽  
2001 ◽  
Vol 68 (3) ◽  
pp. 279-285 ◽  
Author(s):  
Charalambos Ladakis ◽  
Pavlos Myrianthefs ◽  
Andreas Karabinis ◽  
Gabriel Karatzas ◽  
Theodosios Dosios ◽  
...  

1992 ◽  
Vol 1 (3) ◽  
pp. 102-106 ◽  
Author(s):  
ML Noll ◽  
RL Fountain ◽  
CA Duncan ◽  
L Weaver ◽  
VP Osmanski ◽  
...  

OBJECTIVE: To determine fluctuation in mixed venous oxygen saturation in critically ill medical patients during a period of rest. DESIGN: Nonexperimental, descriptive. SETTING: The medical and coronary intensive care units in a large county hospital in south-central Texas. PATIENTS: Twenty critically ill patients, aged 19 to 85, who had placement of a pulmonary artery catheter capable of continuous monitoring of mixed venous oxygen saturation. The majority had a diagnosis of respiratory failure and required mechanical ventilation. METHODS: Mixed venous oxygen saturation was recorded each minute for a 2-hour period in either early morning or late afternoon hours. Minute-by-minute values obtained during a 30-minute period of rest were used to determine fluctuation. The lowest and highest mixed venous oxygen saturation values during the period were used to calculate percent changes from average values (fluctuation). RESULTS: The range of fluctuation was +/- 6% of the average mixed venous oxygen saturation value for 80% of the sample. Four patients had a greater range of fluctuation: however, their actual mixed venous oxygen saturation values were within a clinically acceptable range. No significant differences in percentage of low or high fluctuation were noted for the following variables: time of day, medication administration, oxygen delivery, oxygen consumption and average mixed venous oxygen saturation. The percentage of low fluctuation was significantly lower for four patients who were not mechanically ventilated. CONCLUSIONS: Knowledge of normal fluctuation enables the care giver to evaluate changes in mixed venous oxygen saturation in response to activities and/or treatments. Additional study of fluctuation in homogenous groups of critically ill patients is warranted.


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