scholarly journals The incidence of tuberculosis among adolescents and young adults: a global estimate

2018 ◽  
Vol 51 (2) ◽  
pp. 1702352 ◽  
Author(s):  
Kathryn J. Snow ◽  
Charalambos Sismanidis ◽  
Justin Denholm ◽  
Susan M. Sawyer ◽  
Stephen M. Graham

Historical data show that the risk of tuberculosis increases dramatically during adolescence, and young people face unique challenges in terms of case detection and effective treatment. However, little is known about the burden of tuberculosis among young people in the modern era. This study aimed to provide the first estimates of the global and regional incidence of tuberculosis among young people aged 10–24 years.Using the World Health Organization (WHO) database of tuberculosis notifications for 2012, we estimated the burden of tuberculosis among young people by WHO region. Adjustments were made for incomplete age disaggregation and underreporting, using supplementary data from several countries representing diverse tuberculosis epidemics.We estimate that 1.78 million (uncertainty interval (UI) 1.23–3.00 million) young people developed tuberculosis in 2012, accounting for 17% of all new tuberculosis cases globally. Young people in the WHO South East Asian Region (721 000, UI 473 000–1.35 million) and the WHO African Region (534 000, UI 359 000–912 000) experienced the greatest number of tuberculosis episodes.Young people suffer a considerable burden of tuberculosis. Age-specific burden of disease estimation for this age group is complicated by incomplete age disaggregation of tuberculosis data, highlighting the importance of continued surveillance system strengthening.

2016 ◽  
Vol 3 (3) ◽  
Author(s):  
Prof. C. G. Venkatesha Murthy

Education is a process of accelerating the rate of maturation among children and adolescence. Both the childhood and adolescence are crucial stages of development, which will have to be channelized healthily in order to create a rich human resource. World Health Organization (WHO) defines individuals in the age group of 10-19 as adolescents, in the age group of 10-24 as young people and in the age group of 15-24 as youth (WHO 2007).


Blood ◽  
2012 ◽  
Vol 120 (4) ◽  
pp. 748-760 ◽  
Author(s):  
Cassandra D. Josephson ◽  
Suzanne Granger ◽  
Susan F. Assmann ◽  
Marta-Inés Castillejo ◽  
Ronald G. Strauss ◽  
...  

Age-group analyses were conducted of patients in the prophylactic platelet dose trial (PLADO), which evaluated the relation between platelet dose per transfusion and bleeding. Hospitalized patients with treatment-induced hypoproliferative thrombocytopenia were randomly assigned to 1 of 3 platelet doses: 1.1 × 1011, 2.2 × 1011, or 4.4 × 1011 platelets/m2 per transfusion, given for morning counts of ≤ 10 000 platelets/μL. Daily hemostatic assessments were performed. The primary end point (percentage of patients who developed grade 2 or higher World Health Organization bleeding) was evaluated in 198 children (0-18 years) and 1044 adults. Although platelet dose did not predict bleeding for any age group, children overall had a significantly higher risk of grade 2 or higher bleeding than adults (86%, 88%, 77% vs 67% of patients aged 0-5 years, 6-12 years, 13-18 years, vs adults, respectively) and more days with grade 2 or higher bleeding (median, 3 days in each pediatric group vs 1 day in adults; P < .001). The effect of age on bleeding differed by disease treatment category and was most pronounced among autologous transplant recipients. Pediatric subjects were at higher risk of bleeding over a wide range of platelet counts, indicating that their excess bleeding risk may be because of factors other than platelet counts. This trial was registered at www.clinicaltrials.gov as #NCT00128713.


PEDIATRICS ◽  
1966 ◽  
Vol 37 (2) ◽  
pp. 392-392
Author(s):  
THOMAS E. CONE

This is a timely, concise, eminently practical, thoughtfully, even tenderly, written 28 page report of a recent WHO Expert Committee meeting on the health problems of adolescence. The members and the consultants to the Committee deftly summarize the major worldwide trends affecting our adolescent population. The size of this population is staggering; in the age group 15-19 years alone there are already 300 million adolescents in the world, and there seems every likelihood that these numbers will increase rapidly during the next decade.


2021 ◽  
Vol 17 ◽  
Author(s):  
Sumel Ashique ◽  
Navjot K Sandhu

: The whole world is facing the current potential life-threatening virus nCOVID-19, the most severe health crisis in the modern era. The World Health Organization (WHO) has announced the nCOVID-19 as a pandemic in global concern. People with diabetes are not more likely to get nCOVID-19 than the general population. However, nCOVID-19 can cause more severe symptoms and complications in some people living with Diabetes. Older individuals and individuals with previous ailments, (such as diabetes, coronary illness, and asthma) have all the earmarks of being more susceptible to nCOVID-19 infection. People having diabetic condition becomes more challenging to treat against nCOVID-19 due to firstly, the insusceptible systemic undermined, making it harder to battle the infection and likely prompting a more drawn out recuperation period and secondly the infection may flourish in a situation of raised blood glucose. Various therapeutic (anti-diabetic drugs) approaches are available to treat diabetic patients from having nCOVID-19. This review mainly focused on the effect of this virus on type diabetic patients, mortality rate, the mechanism involved, associated complications, and the role of vitamin D, Zn, therapeutics, and prevention procedure.


2021 ◽  
Vol 32 (3) ◽  
pp. 1320-1338
Author(s):  
Jose Luis Hernandez Caceres ◽  
Graham Wright ◽  
Berhanu Dibaba Kumma ◽  
Frank Verbeke ◽  
Yury Nechipurenko

Author(s):  
Shazia Ali ◽  
Amat Us Samie ◽  
Asma Ali ◽  
Aashiq Hussain Bhat ◽  
Tariq Mir ◽  
...  

Global health issues are a global burden and are relatively common in industrialized societies. The World Health Organization and researchers have developed and rebuilt tools to report the burden of disease affecting mortality and health of the people. Apart from America and Europe, which are at an average of global burden for mental health disease, in some regions it is a major priority to be addressed globally. In South East Asia, one of the affected regions is Kashmir, Northern Indian. Disasters have manifested in various forms encompassing the natural calamities of earthquake, flood, landslides and manmade calamities of violence. Trauma due to manmade calamities has taken over as a leading cause of morbidity and mortality among the most productive working age group of 12-35 years. The chapter aims to understand the patterns of resilience in people surviving war and conflict in Kashmir over last 60 years. The focus is on the young population of society. Generations in Kashmir have faced the psychosocial impact of ongoing political conflict since the 1980's.


Author(s):  
Andreas Wölfl

The prevention of youth violence is one of the major challenges of our time. Based on important key concepts on youth violence from the report of the World Health Organization, opportunities are presented for music therapy with youth to prevent violence. As music in its various forms reaches a very large number of young people all around the world on an emotional level, it is important to note its special ability to promote aggressive emotions as well as to regulate these same emotions. Integrated with more mainstream approaches, music therapy can have preventive potential at different levels: in individual settings, group programmes, and community approaches. Different music therapy approaches for the challenges of violence prevention are presented and developmental tasks for the future are discussed.


2018 ◽  
Vol 10 (12) ◽  
pp. 4789 ◽  
Author(s):  
Stephanie James ◽  
Karen Tountas

After years of success in reducing the global malaria burden, the World Health Organization (WHO) recently reported that progress has stalled. Over 90% of malaria deaths world-wide occurred in the WHO African Region. New tools are needed to regain momentum and further decrease the burden of malaria. Gene drive, an emerging technology that can enhance the inheritance of beneficial genes, offers potentially transformative solutions for overcoming these challenges. Gene drives may decrease disease transmission by interfering with the growth of the malaria parasite in the mosquito vector or reducing mosquito reproductive capacity. Like other emerging technologies, development of gene drive products faces technical and non-technical challenges and uncertainties. In 2018, to begin addressing such challenges, a multidisciplinary group of international experts published comprehensive recommendations for responsible testing and implementation of gene drive-modified mosquitoes to combat malaria in Sub-Saharan Africa. Considering requirements for containment, efficacy and safety testing, monitoring, stakeholder engagement and authorization, as well as policy and regulatory issues, the group concluded that gene drive products for malaria can be tested safely and ethically, but that this will require substantial coordination, planning, and capacity development. The group emphasized the importance of co-development and co-ownership of products by in-country scientists.


Author(s):  
Shazia Ali ◽  
Amat Us Samie ◽  
Asma Ali ◽  
Aashiq Hussain Bhat ◽  
Tariq Mir ◽  
...  

Global health issues are a global burden and are relatively common in industrialized societies. The World Health Organization and researchers have developed and rebuilt tools to report the burden of disease affecting mortality and health of the people. Apart from America and Europe, which are at an average of global burden for mental health disease, in some regions it is a major priority to be addressed globally. In South East Asia, one of the affected regions is Kashmir, Northern Indian. Disasters have manifested in various forms encompassing the natural calamities of earthquake, flood, landslides and manmade calamities of violence. Trauma due to manmade calamities has taken over as a leading cause of morbidity and mortality among the most productive working age group of 12-35 years. The chapter aims to understand the patterns of resilience in people surviving war and conflict in Kashmir over last 60 years. The focus is on the young population of society. Generations in Kashmir have faced the psychosocial impact of ongoing political conflict since the 1980's.


2019 ◽  
Vol 4 (2) ◽  
pp. 222-237
Author(s):  
Aruni Wijayath

Female genital mutilation (FGM) is a ritual and religious and cultural practice among the Moor, Malay and Dawoodi Bohra ethnic communities in Sri Lanka. The process of FGM is ensconced from the general public in Sri Lanka; therefore, few pieces of research pertaining to the practice of FGM are available. A considerable number of international organizations profess that the percentage of FGM/cutting is zero in Sri Lanka through their reports, although newspaper articles and country reports disclose that FGM actually exists among the Muslim community in Sri Lanka. The knowledge regarding the process of FGM is in the backwater in Sri Lanka, even though a considerable number of feminism activists have created a platform to discuss the bad consequences emerging from this harmful practice. According to the World Health Organization (WHO), 30 countries of African Region, selected countries in the Middle East, and countries of Asian Region practice this custom among the female community in some ethnic and religious groups. Through this practice, the female community has not gained any advantage or benefit. The purpose of this research is to explore the municipal laws and human rights regarding FGM in the Sri Lankan context. Furthermore, international conventions which are ratified by Sri Lanka will be analysed in this manner. This research is mainly based on the normative method and retrieved Internet documentary analysis in a qualitative manner.


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