scholarly journals Evaluation of severity score-guided approaches to macrolide use in community-acquired pneumonia

2017 ◽  
Vol 50 (3) ◽  
pp. 1602306 ◽  
Author(s):  
Aran Singanayagam ◽  
Stefano Aliberti ◽  
Catia Cillóniz ◽  
Antoni Torres ◽  
Francesco Blasi ◽  
...  
Keyword(s):  
Severity Score ◽  
Community Acquired Pneumonia

scholarly journals Expanded CURB-65: a new score system predicts severity of community-acquired pneumonia with superior efficiency

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Jin-liang Liu ◽  
Feng Xu ◽  
Hui Zhou ◽  
Xue-jie Wu ◽  
Ling-xian Shi ◽  
...  
Keyword(s):  
Severity Score ◽  
Community Acquired Pneumonia ◽  
Score System ◽  
Pneumonia Severity ◽  
Increased Risk ◽  
Severity Scores ◽  
Low Blood Pressure ◽  
Health Care Associated Pneumonia ◽  
Score Systems ◽  
Better Than

Abstract Aim of this study was to develop a new simpler and more effective severity score for community-acquired pneumonia (CAP) patients. A total of 1640 consecutive hospitalized CAP patients in Second Affiliated Hospital of Zhejiang University were included. The effectiveness of different pneumonia severity scores to predict mortality was compared, and the performance of the new score was validated on an external cohort of 1164 patients with pneumonia admitted to a teaching hospital in Italy. Using age ≥ 65 years, LDH > 230 u/L, albumin < 3.5 g/dL, platelet count < 100 × 109/L, confusion, urea > 7 mmol/L, respiratory rate ≥ 30/min, low blood pressure, we assembled a new severity score named as expanded-CURB-65. The 30-day mortality and length of stay were increased along with increased risk score. The AUCs in the prediction of 30-day mortality in the main cohort were 0.826 (95% CI, 0.807–0.844), 0.801 (95% CI, 0.781–0.820), 0.756 (95% CI, 0.735–0.777), 0.793 (95% CI, 0.773–0.813) and 0.759 (95% CI, 0.737–0.779) for the expanded-CURB-65, PSI, CURB-65, SMART-COP and A-DROP, respectively. The performance of this bedside score was confirmed in CAP patients of the validation cohort although calibration was not successful in patients with health care-associated pneumonia (HCAP). The expanded CURB-65 is objective, simpler and more accurate scoring system for evaluation of CAP severity, and the predictive efficiency was better than other score systems.

scholarly journals A new severity score for community-acquired pneumonia: PARB score

Critical Care ◽  
2010 ◽  
Vol 14 (Suppl 1) ◽  
pp. P253 ◽  
Author(s):  
N Uchiyama ◽  
R Suda ◽  
S Yamao ◽  
Y Tomishima ◽  
T Jinta ◽  
...  
Keyword(s):  
Severity Score ◽  
Community Acquired Pneumonia

Chest physiotherapy in paediatric patients hospitalised with community-acquired pneumonia: a randomised clinical trial

2012 ◽  
Vol 97 (11) ◽  
pp. 967-971 ◽  
Author(s):  
Janice Luisa Lukrafka ◽  
Sandra C Fuchs ◽  
Gilberto Bueno Fischer ◽  
José A Flores ◽  
Jandira M Fachel ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Respiratory Rate ◽  
Severity Score ◽  
Body Position ◽  
Community Acquired Pneumonia ◽  
Chest Physiotherapy ◽  
Secondary Outcome ◽  
Control Group ◽  
Breathing Exercises ◽  
Significant Difference

BackgroundChest physiotherapy has been used to treat children hospitalised with pneumonia with no clear scientific evidence to support a beneficial effect. The objective of the current study was to evaluate the efficacy of chest physiotherapy as an adjuvant treatment in children hospitalised with acute community-acquired pneumonia.MethodsChildren (aged 1–12 years) with a clinical and confirmed radiological diagnosis of pneumonia sequentially admitted to a tertiary children hospital were eligible for this study. Participants were randomly selected to receive a standardised respiratory physiotherapy (positioning, thoracic vibration, thoracic compression, positive expiratory pressure, breathing exercises and forced exhalation with the glottis open or ‘huffing’) three times daily in the ‘intervention group’ or a non-mandatory request to breathe deeply, expectorate the sputum and maintain a lateral body position once a day in the ‘control group’. The primary outcomes were reduction in respiratory rate and severity score (respiratory rate, recession, fever, oxygen saturation and chest x-ray) from baseline to discharge. Secondary outcome was duration of hospitalisation.ResultsIn all, 72 patients were randomly allocated to the intervention (n=35) or control (n=37) groups. There were no differences at admission on severity of pneumonia between groups. Respiratory rate and severity score significant decreased between admission to discharge within each group; however, there were no differences when comparing groups. Also, there was no significant difference in duration of hospitalisation between the control and intervention groups (6 vs 8 days, p=0.11, respectively).ConclusionsThis clinical trial suggests that, in children hospitalised with moderate community-acquired pneumonia, chest physiotherapy did not have clinical benefits in comparison to control group.

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