The Screening and Categorization of Patients: A Case for Natural Selection?

1987 ◽  
Vol 14 (3) ◽  
pp. 181-186 ◽  
Author(s):  
N. R. E. Robertson ◽  
M. L. Jones ◽  
S. Richmond ◽  
E. May

A preliminary study was performed on the feasibility and validity of objective categorization of patients into basic ‘treatment types’. The Reflex Metrograph was used for a three-dimensional cast analysis, and an H.P. 9874 A digitizer was used for a two-dimensional radiograph analysis. In both measurement techniques the method error was found to be acceptable. Using the Ricketts 10 Factor Analysis, it was found that by means of ‘Clinical deviators’ radiographs could be used to distinguish orthognathic cases from the other treatment groups. The three-dimensional study cast analysis showed promise, distinguishing a number of statistically significant factors within the lower arch and between simple and fixed appliance cases. A number of variables which might have been expected to be significant were confounded by their range of values within the groups. Further investigation is required with an improved technique of initial categorization of patients, perhaps by means of a panel of clinicians, and more sophisticated statistical techniques.

2021 ◽  
Vol 11 (4) ◽  
pp. 1670
Author(s):  
Tetsuya Mimura ◽  
Shinpei Okawa ◽  
Hiroshi Kawaguchi ◽  
Yukari Tanikawa ◽  
Yoko Hoshi

Thyroid cancer is usually diagnosed by ultrasound imaging and fine-needle aspiration biopsy. However, diagnosis of follicular thyroid carcinomas (FTC) is difficult because FTC lacks nuclear atypia and a consensus on histological interpretation. Diffuse optical tomography (DOT) offers the potential to diagnose FTC because it can measure tumor hypoxia, while image reconstruction of the thyroid is still challenging mainly due to the complex anatomical features of the neck. In this study, we attempted to solve this issue by creating a finite element model of the human neck excluding the trachea (a void region). By reconstruction of the absorption coefficients at three wavelengths, 3D tissue oxygen saturation maps of the human thyroid are obtained for the first time by DOT.


2011 ◽  
Vol 56 (3) ◽  
pp. 766-770 ◽  
Author(s):  
Delphine Tardivo ◽  
Julien Sastre ◽  
Michel Ruquet ◽  
Lionel Thollon ◽  
Pascal Adalian ◽  
...  

2006 ◽  
Vol 96 (3) ◽  
pp. 212-219 ◽  
Author(s):  
Simon K. Spooner ◽  
Kevin A. Kirby

A new clinical device, the subtalar joint axis locator, was created to track the three-dimensional location of the subtalar joint axis during weightbearing movements of the foot. The assumption was that if the anterior exit point of the subtalar joint axis is stationary relative to the dorsal aspect of the talar neck, then, by performing radiographs of the feet with the subtalar joint axis locator in place on the foot, the ability of the locator to track rotations and translations of the talar neck and thus the subtalar joint axis in space could be approximated. In this preliminary study of two adults, the subtalar joint axis locator accurately tracked the talar neck position during weightbearing rotational motions of the subtalar joint. The device was also used in a series of subjects to determine its dynamic capabilities. It is possible, then, that the subtalar joint axis locator can reliably track the spatial location of the subtalar joint axis during weightbearing movements of the foot. (J Am Podiatr Med Assoc 96(3): 212–219, 2006)


2010 ◽  
Vol 126-128 ◽  
pp. 690-695
Author(s):  
David Lee Butler

Surface measurement using three-dimensional stylus instruments is a relatively new technique that offers numerous advantages over more traditional profilometry methods. The information generated is, unlike profile measurement, less subjective and more statistical providing additional insight into the surface structure. One application of surface measurement that has encountered problems when using the profilometry method is that of grinding wheel characterisation. The wheel surface texture (topography) and the conditions under which it is generated have a profound effect upon the grinding performance as characterised by the grinding forces, power consumption, temperature, and surface integrity of components. A detailed knowledge of the nature of the topography of the grinding wheel would provide further insight into surface interactions between the wheel and workpiece as well as enabling improved control of the grinding process in general. In this paper four diamond grinding wheels of 91 and 181 micron grit size were subjected to differing dressing conditions to produce varying final wheel topographies. Three-dimensional surface measurement techniques were employed to quantitatively characterise the topographic change and provide an aerial estimation of the number of cutting grains. The results demonstrate that the techniques can distinguish between a worn and dressed wheel. In addition, the parametric values generated from the various surfaces can aid the user in determining when re-dressing is required.


2021 ◽  
Author(s):  
Xiu-Heng Zhang ◽  
Heng Zhang ◽  
Zhen Li ◽  
Gui-Bin Bian

Abstract Three-dimensional force perception is critically important in the enhancement of human force perception to minimize brain injuries resulting from excessive forces applied by surgical instruments in robot-assisted brain tumor resection. And surgeons are not responsive enough to interpret tool-tissue interaction forces. In previous studies, various force measurement techniques have been published. In neurosurgical scenarios, there are still some drawbacks to these presented approaches to forces perception. Because of the narrow, and slim configuration of bipolar forceps, three-dimensional contact forces on forceps tips is not easy to be traced in real-time. Five fundamental acts of handling bipolar forceps are poking, opposing, pressing, opening, and closing. The first three acts independently correspond to the axial force of z, x, y. So, in this paper, typical interactions between bipolar forceps and brain tissues have been analyzed. A three-dimensional force perception technique to collect force data on bipolar forceps tips by installing three Fiber Bragg Grating Sensors (FBGs) on each prong of bipolar forceps in real-time is proposed. Experiments using a tele-neurosurgical robot were performed on an in-vitro pig brain. In the experiments, three-dimensional forces were tracked in real-time. It is possible to experience forces at a minimum of 0.01 N. The three-dimensional force perception range is 0-4 N. The calibrating resolution on x, y, and z, is 0.01, 0.03, 0.1 N, separately. According to our observation, the measurement accuracy precision is over 95%.


2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
Joshua Burke ◽  
Jack Helliwell ◽  
Mikolaj Kowal ◽  
David Jayne

Abstract Aim Platelet-rich fibrin (PRF) is a three-dimensional fibrin scaffold with associated platelets and leukocytes which releases high quantities of growth factors over a sustained period of time. PRF has shown promising clinical results in promoting wound healing and tissue regeneration. The aims of this feasibility study were to establish optimal spinning methods for production of PRF, to quantify the production of vascular endothelial growth factor (VEGF) by PRF and to explore new vehicles of clinical PRF delivery. Method Assessment of optimal production involved comparisons between Protocol 1 (EDTA bottle) and Protocol 2 (no additive) at three different centrifugation forces: 400g, 1000g and 1700g. VEGF production was analysed using ELISA with varied incubation periods and PRF plug segments. Novel methods for PRF delivery were explored using surgical sutures and a Zimmer® Skin Graft Mesher. Results Protocol 2 demonstrated shorter average time to blood draw (9.8s compared to 13.6s) and to centrifuge (25.5s compared to 33.1s) with a decreased range of values. All PRF segments exhibited a positive correlation between incubation time and amount of VEGF produced with the bottom segments producing on average more VEGF. A segment of the fibrin plug was successfully secured on a suture and meshed in a 1:1.5 ratio. Conclusions PRF production can be optimised using blood bottles with no additive and high centrifugation forces. VEGF production by PRF peaks at 120 hours with the bottom PRF segment exhibiting the highest rate of production. The first description of a PRF mesh enables new clinical applications.


2018 ◽  
Vol 35 ◽  
pp. 03002 ◽  
Author(s):  
Sławomir Porzucek ◽  
Monika Łój ◽  
Karolina Matwij ◽  
Wojciech Matwij

In the region of Siesławice (near Busko-Zdrój, Poland) there are unique phenomena of gypsum karst. Atmospheric factors caused numerous gypsum outcrops, canals and underground voids. The article presents the possibility of using non-invasive gravimetric surveys supplemented with geodetic measurements to illustrate karst changes occurring around the void. The use of modern geodetic measurement techniques including terrestrial and airborne laser scanning enables to generate a digital terrain model and a three-dimensional model of voids. Gravimetric field studies allowed to map the anomalies of the gravitational field of the near-surface zone. Geodetic measurement results have made it possible to accurately determine the terrain correction that supplemented the gravimetric anomaly information. Geophysical interpretation indicate the presence of weathered rocks in the near surface zone and fractures and loosened zones located surround the karst cave.


Sign in / Sign up

Export Citation Format

Share Document