scholarly journals THE REDUCTION OF TETRAZOLIUM SALTS BY ASCITES TUMOR CELLS IN THE PRESENCE OF GLUCOSE

1958 ◽  
Vol 6 (3) ◽  
pp. 174-180 ◽  
Author(s):  
T. BARKA ◽  
G. DALLNER
Keyword(s):  
Tumor Cells ◽  
Ehrlich Ascites Tumor ◽  
Ehrlich Ascites Tumor Cells ◽  
Ascites Tumor ◽  
Electron Carrier ◽  
Tetrazolium Salts ◽  
Qualitative And Quantitative ◽  
Ehrlich Ascites

The Ehrlich ascites tumor cells reduce tetrazolium salts intensely in the presence of glucose. The analysis of this glucose staining indicates the role of an electron-carrier in the glycolysis, probably of glycerolaldehyde-dehydrogenase. The qualitative and quantitative aspects of glucose-staining were investigated and discussed.

Role of orthophosphate concentration in the regulation of ribose phosphate synthesis and purine metabolism in Ehrlich ascites tumor cells

1977 ◽  
Vol 55 (8) ◽  
pp. 834-840 ◽  
Author(s):  
Jerzy Barankiewicz ◽  
Mary L. Battell ◽  
J. Frank Henderson
Keyword(s):  
Tumor Cells ◽  
Purine Metabolism ◽  
Ehrlich Ascites Tumor ◽  
Ehrlich Ascites Tumor Cells ◽  
Ascites Tumor ◽  
Phosphoribosyl Pyrophosphate ◽  
Ribose Phosphate ◽  
Ehrlich Ascites ◽  
In Cells

Concentrations of intracellular orthophosphate were determined in Ehrlich ascites tumor cells incubated with glucose, inosine, or uridine in media of different orthophosphate concentration. The effects of orthophosphate concentration on the accumulation of lactate and of phosphoribosyl pyrophosphate and on concentrations of ribose 1-phosphate and ribose 5-phosphate in tumor cells incubated with glucose were also determined. Both the phosphorolysis of inosine and the rate of catabolism of ATP in cells incubated with 2-deoxyglucose were also influenced by the orthophosphate concentration of the medium.

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