scholarly journals Effect of Lipodystrophy on the Quality of Life among People Living with HIV (PLHIV) on Highly Active Antiretroviral Therapy

2013 ◽  
Vol 13 (5) ◽  
pp. 471-475 ◽  
Author(s):  
Archana Shenoy ◽  
John T. Ramapuram ◽  
Bhaskaran Unnikrishan ◽  
Basavaprabhu Achappa ◽  
Deepak Madi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
People Living With Hiv ◽  
Highly Active ◽  
Living With Hiv

scholarly journals Behavioral and Psychosocial Factors of Quality of Life Among Adult People Living With HIV on Highly Active Antiretroviral Therapy, in Public Hospitals of South West Ethiopia, 2018: a Case Control Study

2020 ◽  
Author(s):  
Abreha Addis Gesese ◽  
Yitages Getachew Desta ◽  
Endale zenebe Behire
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Poor Quality ◽  
Public Hospitals ◽  
People Living With Hiv ◽  
Khat Chewing ◽  
Highly Active ◽  
Living With Hiv

Abstract Background: Despite of the availability of Highly Active Antiretroviral Therapy, people living with HIV/AIDS suffer from socioeconomic, behavioral and psychosocial related factors affecting their quality of life. Previous studies assessed the magnitude of quality of life but the present one will identify behavioral and psychosocial factors associated with poor quality of live among adult PLWHIV on Antiretroviral therapy in the study setting.Objective: To identify behavioral and psychosocial determinants of Quality of life among Adult PLWHIV on HARRT, in Public Hospitals of Jimma Zone, South West, Ethiopia 2018.Method: Institution based unmatched case control study was employed. Simple random sampling technique was used to select cases and controls using screening criteria. Interviewer administered data collection method was used. Data were entered into Epi-Data and analyzed using SPSS version 20. Bivariate and multivariate logistic regressions were performed. The study was conducted from March 10-April 10- 2018.Results: A total of 75(25%) cases and 225(75%) of controls included in the study. Finally, the odds of poor quality of life among underweight (BMI kg/m2) 2.7 times [AOR 2.7 95%CI (1.0, 7.1)] more likely than normal /obese respondents, khat chewing 1-4 times/weak/month about 4.5 times [AOR 4.5 95%CI (1.85, 10.9)] and at daily intervals 4.7 times more [AOR 4.7 95% CI (1.18, 18.8)] likely than who never chew respectively. Being dissatisfied from support AOR 9.8 95% CI (1.9, 50), Stigmatized patients 8 times more likely than non-stigmatized AOR 8.0 95%CI (3.6, 18.1). Moreover, the odds of poor quality of life among severely depressed patients were 4 times AOR 4.0 95% CI (1.67, 9.83) more likely than mild depressed patients.Conclusion: Being underweight (BMI kg/m2), khat chewing 1-4 times/weak/month, khat chewing at daily interval, being dissatisfied from support, stigma and depression were independently associated. This may inform possible interventions to reduce comorbidities and disease exacerbation by improving on dietary and nutritional programs and support, reducing behavioral factors, improving social support, reducing stigma and depression by appropriate counseling and strengthening currently existing Information Education Communication to help develop life skills.

scholarly journals Behavioral and Psychosocial Factors of Quality of Life Among Adult People Living With HIV on Highly Active Antiretroviral Therapy, in Public Hospitals of South West Ethiopia, 2018: a Case Control Study

2020 ◽  
Author(s):  
Abreha Addis Gesese ◽  
Yitages Getachew Desta ◽  
Endale zenebe Behire
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Poor Quality ◽  
Public Hospitals ◽  
People Living With Hiv ◽  
Khat Chewing ◽  
Highly Active ◽  
Living With Hiv

Abstract Background: Despite of the availability of Highly Active Antiretroviral Therapy, people living with HIV/AIDS suffer from socioeconomic, behavioral and psychosocial related factors affecting their quality of life. Previous studies assessed the magnitude of quality of life but the present one will identify behavioral and psychosocial factors associated with poor quality of live among adult PLWHIV on Antiretroviral therapy in the study setting.Objective: To identify behavioral and psychosocial determinants of Quality of life among Adult PLWHIV on HARRT, in Public Hospitals of Jimma Zone, South West, Ethiopia 2018.Method: Institution based unmatched case control study was employed. Simple random sampling technique was used to select cases and controls using screening criteria. Interviewer administered data collection method was used. Data were entered into Epi-Data and analyzed using SPSS version 20. Bivariate and multivariate logistic regressions were performed. The study was conducted from March 10-April 10- 2018.Results: A total of 75(25%) cases and 225(75%) of controls included in the study. Finally, the odds of poor quality of life among underweight (BMI kg/m2) 2.7 times [AOR 2.7 95%CI (1.0, 7.1)] more likely than normal /obese respondents, khat chewing 1-4 times/weak/month about 4.5 times [AOR 4.5 95%CI (1.85, 10.9)] and at daily intervals 4.7 times more [AOR 4.7 95% CI (1.18, 18.8)] likely than who never chew respectively. Being dissatisfied from support AOR 9.8 95% CI (1.9, 50), Stigmatized patients 8 times more likely than non-stigmatized AOR 8.0 95%CI (3.6, 18.1). Moreover, the odds of poor quality of life among severely depressed patients were 4 times AOR 4.0 95% CI (1.67, 9.83) more likely than mild depressed patients.Conclusion: Being underweight (BMI kg/m2), khat chewing 1-4 times/weak/month, khat chewing at daily interval, being dissatisfied from support, stigma and depression were independently associated. This may inform possible interventions to reduce comorbidities and disease exacerbation by improving on dietary and nutritional programs and support, reducing behavioral factors, improving social support, reducing stigma and depression by appropriate counseling and strengthening currently existing Information Education Communication to help develop life skills.

scholarly journals Gender Differences in Health Related Quality of Life among People Living with HIV on Highly Active Antiretroviral Therapy in Mekelle Town, Northern Ethiopia

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Amanuel Tesfay ◽  
Abebe Gebremariam ◽  
Mulusew Gerbaba ◽  
Hailay Abrha
Keyword(s):  
Quality Of Life ◽  
Gender Differences ◽  
Antiretroviral Therapy ◽  
People Living With Hiv ◽  
Health Related Quality ◽  
Highly Active ◽  
Related Quality ◽  
Health Related ◽  
Living With Hiv

Background. Health related quality of life (HRQOL) is an important outcome measure for highly active antiretroviral treatment program. In Ethiopia, studies revealed that there are improved qualities of life among adults living with the viruses taking antiretroviral therapy but there is no explicit data showing gender differences in health related quality of life.Aim. To assess gender differences in HRQOL and its associated factors among people living with HIV and on highly active antiretroviral therapy in public health institutions of Mekelle town, Northern Ethiopia.Methods. A comparative cross-sectional study was conducted among 494 adult people living with HIV taking ART services. Quality of life was measured using WHOQOL-HIV BREF.Result. There was a statistically significant gender difference (P<0.05) in HRQOL among PLHIV on HAART. Females had low score in all HRQOL domains. High perceived stigma was strongly associated with poor psychological quality of domain among both female and male groups with[AOR=2.89(1.69,4.96)]and[AOR=2.5(1.4,4.4)], respectively.Conclusion. There was statistically significant gender difference in all quality of life domains. Public health interventions to improve HRQOL of PLHIV should take in to account the physical, psychological, social, environmental, and spiritual health of PLHIV during treatment, care, and support.

scholarly journals Assessment of ART knowledge and adherence to ARVs among PLWHA accessing care in two Nigerian Military HIV/AIDS Treatment sites

2018 ◽  
Vol 4 (1) ◽  
pp. 43-52
Author(s):  
David Ufuoma Adje ◽  
Felicia Esemekiphorar Williams ◽  
Chukwuka Nicholas Bezugbe ◽  
Dauda Audi Dangiwa
Keyword(s):  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
People Living With Hiv ◽  
Systematic Random Sampling ◽  
Highly Active ◽  
Study Sites ◽  
Living With Hiv ◽  
Busy Schedule ◽  
Hiv Aids

Background:       Adherence to Highly Active Antiretroviral Therapy (HAART) is critical in achieving treatment goals, avoiding antimicrobial resistance, preventing treatment failure and improving the patient’s quality of life. Objectives: To assess the knowledge of antiretroviral therapy (ART) and adherence to antiretroviral (ARVs) medicines amongst People Living With HIV/AIDS (PLWHA) accessing care in two Nigerian Military HIV/AIDS Treatment sites. Methods: Four hundred patients on HAART who visited the study sites during the study period were recruited for the study using systematic random sampling method. A semi-structured, pretested, interviewer-administered questionnaire was used to obtain demographic details. Patients’ knowledge of HIV was assessed using an 8-item questionnaire while adherence was measured using the Simplified Medication Adherence Questionnaire (SMAQ). Results: The predominant age group was 31-40 years (46.4%). There were more females (69%) than males (31%). Only 45.5% answered knowledge questions correctly. The adherence level in this study was 64.0%. The major reasons cited for non-adherence included being away from home (23.6%), forgetfulness (17.1%), busy schedule (14%), need to conceal medication (12.7%) and feeling better (11.6%). Conclusion: Patients’ knowledge of ART and adherence to ARVs medicines were sub-optimal. Appropriate strategies to improve patients’ knowledge of ART and adherence to ARVs are recommended.

scholarly journals A cross-sectional study on caregivers’ perspective of the quality of life and adherence of paediatric HIV patients to Highly Active Antiretroviral Therapy 

2020 ◽  
Author(s):  
Michael Lahai ◽  
Peter Bai. James ◽  
Noel N. Wannang ◽  
Haja R. Wurie ◽  
Sorie Conteh ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Nuclear Family ◽  
Strong Association ◽  
Hiv Positive ◽  
Cross Sectional ◽  
Highly Active ◽  
Health Domains

Abstract Background: Poor compliance to highly active antiretroviral therapy (HAART) can result in the poor quality of life in children living with HIV/AIDS because of low plasma drug concentration and the possibility of drug resistance. This study evaluates the response of caregivers for determination of adherence and the four quality of life domains in children (aged 14 years and under) on HAART.Methods: We conducted a cross-sectional study of 188 children, each accompanied by their caregivers at Ola During Children's Hospital and Makeni Government Hospital between September and November 2016. Adherence to HAART and Quality of life was assessed using the WHO Quality of life summary questionnaire (WHOQOL-BREF). We obtained ethical approval from the Sierra Leone Ethics and Scientific Review Committee. Results: The study revealed 5.9% adherence amongst paediatric patients, and a strong association of adherent patients(p=0.019*) to the physical health domain (mean=64.61 SD=8.1).Caregiver HIV status showed a strong association with the physical (mean=58.3, SD=11.7 and p=0.024*), and psychological health domains (mean=68.2, SD=14.7 and p=0.001). Caregiver type (mother/father/sibling) accompanying child to hospital also showed strong associated with the physical (mean=58.0, SD=10.6, p <0.001), psychological (mean 68.2 SD=14.81 p <0.001) and environmental health domains (mean=59.7, SD=13.47, p <0.001). Further regression analysis showed a strong association with physical health domain for HIV positive caregivers (p=0.014) and adherent paediatric patients (p=0.005). Nuclear family also showed a strong association with psychological (p<0.001) and environmental (p=0.001) health domains. Conclusion: This study showed a strong association between the quality of life domains and the involvement of nuclear family caregiver, HIV-positive caregiver and adherence to HAART. Our study suggests that the involvement of any member of the nuclear family, HIV positive parents and patient adherence to therapy can improve the quality of life of paediatric HIV/AIDS patients on highly active antiretroviral therapy in the two hospitals.

scholarly journals Adherence to Highly Active Antiretroviral Therapy and Its Association with Serostatus Disclosure among People Living with HIV in Ethiopia:  A Systematic Review and Meta-Analysis.

2020 ◽  
Author(s):  
Abere Woretaw Azagew ◽  
Chilot Kassa Mekonnen ◽  
Abebaw Jember Ferede ◽  
Kassahun Gebeyehu Yazew ◽  
Zewdu Baye Tezera
Keyword(s):  
Systematic Review ◽  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Assessment Tool ◽  
Meta Analysis ◽  
People Living With Hiv ◽  
Serostatus Disclosure ◽  
Highly Active ◽  
Pooled Prevalence ◽  
Living With Hiv

Abstract Background: Adherence to highly active antiretroviral therapy (HAART) is a public health challenge worldwide. Non-adherence to HAART leads to treatment, immunologic, and virological failure. Despite different interventions made, adherence to HAART among adult people living with HIV (PLWHIV) is still inconsistent across studies, and the effect of serostatus disclosure on adherence to HAART was not studied in Ethiopia. Therefore, the study is aimed to determine the pooled prevalence of adherence to HAART and its relationship with serostatus disclosure among adult PLWHIV in Ethiopia.Methods: We searched 3247 original articles, both published and unpublished on Ethiopia dated from January 2016 to November 2019 by using different search engines. Data were extracted using Microsoft excel. New Castle Ottawa Scale quality assessment tool was used. STATA software version 11 was used for analysis. A random-effects model for meta-analysis was computed. Cochran Q statistics and I2 were used to estimate heterogeneity. Egger’s and Begg’s test was used to assess the publication bias.Results: A total of fifteen articles for systematic review and four articles for meta-analysis were used. The pooled prevalence of adherence to HAART is found to be 81.19% (80.1, 82.3). In the subgroup analysis, the pooled prevalence of adherence to HAART was 79.82% (73.19, 86.45) in the Oromia region, 82.51 %( 73.14, 91.87) in the Amhara region, and 72.7% (63.78, 81.61) in the Southern Nations Nationalities and Peoples’ Region (SNNPR). The serostatus disclosure improves adherence to HAART by nearly three times compared to non-serostatus disclosed PLWHIV (AOR=2.99, 95 %CI: 1.88, 4.77).Conclusions: The pooled prevalence of adherence to HAART among adult PLWHIV in Ethiopia was found to be low compared to WHO antiretroviral treatment recommendations. Having serostatus disclosure improved adherence to HAART.

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