scholarly journals Update on male hormonal contraception

2019 ◽  
Vol 10 ◽  
pp. 204201881983484 ◽  
Author(s):  
Giulia Gava ◽  
Maria Cristina Meriggiola

Despite increases in female contraceptive options, 40–45% of pregnancies across the world are still unplanned. While several effective female contraceptive methods have been developed, contraceptive choices for men are still limited to the male condom with its high failure rates and to vasectomies, which are invasive and not reliably reversible. Several studies have demonstrated a great interest among men and women for effective, reversible, and safe male contraceptive methods. Over the years, numerous studies have been performed to develop male hormonal and nonhormonal safe and effective contraceptives. A variety of new molecules are under development as oral or transdermal hormonal contraceptives for men demonstrating few side effects. In our overpopulated world, the development and commercialization of a male contraceptive method that will allow both men and women to take an active role in family planning is mandatory and further research on this topic is required.

2021 ◽  
Vol 4 (4) ◽  
pp. 771-778
Author(s):  
Martina Bedho ◽  
Khrispina Owa ◽  
Yoseph Woge ◽  
Fitria Syafrudin Pua Sawa

ABSTRAK Peserta KB aktif dan akseptor KB baru di kabupaten Ende 53,2 %, lebih memilih menggunakan alat kontrasepsi hormonal sedangkan pemilihan alat kontrasepsi lain berada dibawah 20%. Alat kontrasepsi suntik yang paling banyak digunakan, berikutnya implant dan pil. Akseptor yang mengalami efek samping kenaikan berat badan dan hipertensi 32 orang (11,03%), dan akseptor terbanyak berada di Puskesmas pembantu Tanjung. Tujuan pengabdian masyarakat ini adalah pemberdayaan akseptor dan kader kesehatan mengenal efek samping penggunaan kontrasepsi hormonal, dimana sasarannya adalah kader dan akseptor. Metode yang digunakan adalah screening,ceramah, diskusi, simulasi dan praktikum oleh khalayak sasaran. Hasil pengabdian masyarakat menunjukan semua akseptor memiliki pengetahuan baik (83,33%) pada pretest sedangkan posttest (100%) namun belum tahu tentang lama penggunaan kontrasepsi hormonal baik secara suntik, implant dan pil. Keterampilan yang dicapai adalah semua kader dan akseptor 28 orang (100%) dapat mengukur tinggi badan, menimbang berat badan, dan mengukur tekanan darah. Diharapkan pengamatan yang intensif dari bidan Pustu Tanjung dan dapat diperdaya oleh kader KB untuk membantu mengawasi efek samping kontrasepsi hormonal. Kunci : Pemberdayaan akseptor dan kader, efek samping kontrasepsi hormonal.                                    ABSTRACT 53.2% of active family planning participants and new family planning acceptors in the Ende district prefer to use hormonal contraceptives while the choice of other contraceptives is below 20%. The most widely used injectable contraceptives are implants and pills. There were 32 acceptors who experienced side effects of weight gain and hypertension (11.03%), and the most acceptors were in the Tanjung auxiliary health center. Research in Kumasi sub-district, Ghana, India, because some acceptors experienced long and heavy menstruation, spotting, no menstruation, and vaginal discharge so they were afraid of modern contraceptive methods (Kimberly Daniels, 2015). The aim of this community service is to empower acceptors and health cadres to recognize the side effects of using hormonal contraceptives, where the targets are cadres and acceptors. The methods used are screening, lectures, discussions, simulations, and practicum by the target audience. The results of community service show that all acceptors have good knowledge (83.33%) at pretest while posttest (100%), but they do not know about the length of time using hormonal contraceptives both by injection, implant, and pill. The skill achieved is that all 28 cadres and acceptors (100%) can measure height, weight body weight, and measure blood pressure. It is hoped that intensive observation from the midwife of Pustu Tanjung and the family planning cadres can help to monitor the side effects of hormonal contraception. Keywords:  Empowerment of acceptors and cadres, side effects of hormonal contraception.


Author(s):  
Eka R Gunardi ◽  
Arnold Soetarso ◽  
Putri Addina

Objective: To understand the modalities used for male hormonal contraception. Methods: Literature review Conclusion: Male contraceptive methods are still limited but hormonal contraceptive methods are being developed. The basic mechanism of male hormonal contraception is to inhibit spermatogenesis by suppression of the hypothalamic-pituitary-testicular axis function. Administration of testosterone or androgen derivative that is given in combination with progestin or GnRH antagonist shows that male hormonal contraceptive is reversible, effective, and acceptable as a male contraceptive method. However, no method of male hormonal contraceptive is ready for clinical use and marketed due to limited studies. [Indones J Obstet Gynecol 2015; 3-4: 239-243] Keywords: GnRH antagonist, male hormonal contraceptive, progestin, testosterone


2009 ◽  
Vol 29 (02) ◽  
pp. 193-196 ◽  
Author(s):  
H. Rott ◽  
A. Kruempel ◽  
G. Kappert ◽  
U. Nowak-Göttl ◽  
S. Halimeh

SummaryThe risk of thromboembolic events (TE) is increased by acquired or inherited thrombo -philias (IT). We know that some hormonal contraceptives also increase the risk of thrombosis, thus, the use of such contraceptives are discussed as contraindications in women with IT. TEs are infrequent events in children and adolescents and in the majority of cases are associated with secondary complications from underlying chronic illness. Although adolescents are not typically considered to be at high-risk for TE, this cohort is frequently using hormonal contraception, leading to an increased risk in cases with unknown IT. The risk of TE with pregnancy alone is higher than associated with combined hormonal contra -ception. Progestin-only methods have not been found to increase the risk of TE with only moderate changes of coagulation proteins compared to normal reference values. Conclusion: Thrombophilic women are good candidates for progestin-only contraceptive methods.


Author(s):  
Mahvish Qazi ◽  
Najmus Saqib ◽  
Sachin Gupta

Background: India with 1.35 billion people is the second most populated country in the world next to China. Total fertility rate of India is 2.2 and the current total fertility rate of Jammu and Kashmir is 1.7 which is still lagging behind various states. This study was conducted to investigate the knowledge, attitude and practices of contraception in women of reproductive age in this set up.Methods: The present cross-sectional study was carried out in patients attending OPD (outpatient department) of Obstetrics and Gynecology at ASCOMS, Jammu, Jammu and Kashmir, India from 1st September 2017 to 31st August 2018. 200 married women aged between 18-49 years were included in this study. Socio-demographic characteristics of the women, their knowledge, attitude and practices on contraception were evaluated with the help of predesigned questionnaire.Results: Out of 200 women, maximum respondents belong to age group of 21-25 years (75.6%). Most of the contraceptive non-users belongs to age below 20 years (62.5%). Majority of respondents were Hindu (70.37%), maximum studied up to secondary level education (84.61%), 70.30% were housewives and 56.58% belongs to middle class. In 45% of respondents, media was the main source of information. Preferred spacing method was condom in 85% of cases. 68% women had knowledge of female sterilization. According to most women, family planning methods are meant for limitations of birth (43%) and 36% meant for spacing of birth. 80% women had positive attitude towards contraceptive usage. 50% experienced side effects with the use of contraceptives. The most common side effect was menstrual irregularities in 25% of cases. Most common reason for not using contraceptive methods among non-respondents were lack of knowledge in 50% of cases.Conclusions: The study showed that inspite of having good knowledge, utilization of contraceptives were less because of large family norm, religious myth, cultural and political barriers. Ignorance regarding use and side effects of various contraceptive methods is another reason for inadequate practice of family planning methods.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hankiz Dolan ◽  
Mu Li ◽  
Deborah Bateson ◽  
Rachel Thompson ◽  
Chun Wah Michael Tam ◽  
...  

Abstract Background In Australia, ethnic Chinese people are one of the largest, youngest and fastest growing overseas-born groups. Yet, little is known about their perceptions of contraceptive methods and their experiences with choosing one. Decisions about contraceptive methods are preference sensitive. Understanding the influencing factors of Chinese migrant women’s contraceptive method choice and practices will help cater to their decision-making needs in a culturally sensitive and responsive way. Methods A qualitative study design underpinned by critical realism approach was used to explore Chinese migrant women’s perceptions and experiences of choosing contraceptive methods. Semi-structured interviews were conducted with 22 women who self-identified as being ethnically Chinese and had been living in Australia for no more than 10 years. The interview guide was adapted from the Ottawa Decision Support Framework. Majority of the interviews were conducted in Mandarin Chinese. Transcribed data was analysed using thematic analysis method. Results Four major themes were identified, including: ‘every medicine is part poison: hormonal contraceptives cause harm to the body’; ‘intrauterine device, a device used in the past for married women’; ‘it takes two (or one) to decide, depending on the relationship dynamics and contraception preferences’; and ‘it is not necessary to seek medical advice in choosing contraceptive methods’. Conclusions Our findings suggest that Chinese migrant women’s perceptions and experiences of choosing contraceptive methods are influenced by complex personal, cultural, societal and inter-relational factors. Chinese migrant women were cautious of using hormonal methods due to fears of side-effects, including reduced or absent menstrual bleeding. Women were also reluctant to consider intrauterine devices as options due to associating them with past experiences of other women and themselves and also fears of potential complications. There was a reluctant attitude towards seeking medical advice regarding contraception due to beliefs that needing to use contraception is not an illness requiring treatment. Such findings are likely to be useful in increasing healthcare professionals’ and policy makers’ understanding of Chinese migrant women’s contraceptive method preferences, beliefs and behaviours. They also help to develop culturally and linguistically sensitive strategies, which goes beyond the provision of contraceptive counselling, in assisting Chinese migrant women’s decision-making needs.


2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
J Perrin ◽  
J Tcherdukian ◽  
A Netter ◽  
E Lechevalier ◽  
F Bretelle ◽  
...  

Abstract Study question Among health professionals involved in contraceptive prescribing, what are the knowledge, professional attitudes and training on male contraceptive methods? Summary answer The health professionals involved in prescribing contraception are not sufficiently trained in male contraception and almost all of them want more. What is known already The most recent large-scale studies show that 70% of couple contraception is provided by women and that the majority of men and women would be willing to adopt male contraception as couple contraception. The medicalization of contraception places the medical profession at the forefront of the acceptability of and information regarding a contraceptive method. However, only one study have evaluated health professionals’ knowledge of the various methods of male contraception (MC), including male hormonal contraception (MHC) and male thermal contraception (MTC). Study design, size, duration Between April 2020 and June 2020, we carried out a descriptive prospective multicentre study in a medical population of 2243 prescribers of couple contraception in France. Participants/materials, setting, methods The participants were obstetrician-gynaecologists, medical gynaecologists, general practitioners or midwives. They completed a three-part numerical questionnaire, including i) sociodemographic characteristics and personal experiences with contraception, ii) knowledge and professional attitudes about male contraception and iii) training on male contraception. Main results and the role of chance The overall participation rate was 19% (340/2243). Condoms and withdrawal were known by 98% and 89% of the population, respectively. Vasectomy was known by 75% of the population and significantly better known by obstetrician-gynaecologists than by medical gynaecologists and general practitioners (p = 0.026). Male hormonal contraception (MHC) and male thermal contraception (MTC) were known by 10% and 23% of the population, respectively, and were significantly better known by medical gynaecologists and general practitioners than by other specialties (p < 0.001). More than half (55%) of the population never or infrequently offered MC during a couple’s contraceptive request consultation. Female practitioners offered MC significantly more often than male practitioners (48% vs. 26%; p = 0.033). Only 14% of the population had ever participated in training on MC, 96% wished to be better trained on MC, and 86% expressed a willingness to participate in such a training. Limitations, reasons for caution The population was mainly representative of medical health practitioners of southeastern France. There was an over-representation of women in all medical specialties, except for midwives. Wider implications of the findings: Our study shows that health professionals involved in contraception have limited knowledge about MC and are eager to have more information about it. To advance the acceptability and dissemination of such contraceptive methods, it seems imperative to provide health professionals with an adapted training program on male contraception. Trial registration number 2020–01–23–03


Author(s):  
Alex Eloho Umuerri ◽  
Ngozi Bibian Okeibunor

The study examined radio family planning messages with particular reference to the nature of the audience influence on communication content by using a chat program on radio in a developing society. The study adopted content analysis research method with a purposive sampling technique and used a radio script having six items for analyses. Results showed that there were more family planning segments for women than for men and, there were more family planning for drugs/pills and materials/implantation than for injection. In addition, there were side effects in the use of family planning just as there were quite a number of frequently asked questions except for condoms-fiesta/kiss. This paper concludes that radio scripts/messages for family planning programs should accommodate more topics/segments of family planning for men and women, specifically, natural methods should be included. Furthermore, radio family planning messages should focus more on the benefits of family planning and specifically the benefits of contraceptive pill and post pill emergency should be examined. Other formats of programs should be employed in the campaign for family planning messages on radio, and development communicators and content developers of radio family planning scripts should explore more areas to make radio messages more robust.


2017 ◽  
Vol 158 (46) ◽  
pp. 1819-1830 ◽  
Author(s):  
Norbert Pásztor ◽  
Borbála Eszter Hegyi ◽  
Attila Badó ◽  
Gábor Németh

Abstract: In certain regions of the world the enormous rate of population growth raises economic and public health concerns and widely accessible contraceptive methods would be desired. In contrast, in other countries the use of effective contraception is a question of individual preferences. Today, most of the reliable contraceptive methods are applied by women, while the options for male methods are quite limited. It is well known that significant portion of pregnancies are still unplanned and several data revealed men’s willingness to take part in family planning. Based on these needs, remarkable efforts have been made to develop a suitable hormonal contraceptive agent for men. With the exogenous suppression of follicle stimulating hormone and luteinizing hormone secretion, the inhibition of the testicular testosterone production and the spermatogenesis can be achieved. In the beginning, testosterone-derivatives, or testosterone-progestin combinations were administered, later synthetic androgen agents were developed. Despite of these efforts, unfortunately, there is no safe, widely feasible male hormonal contraception to date, but in the future this goal can be achieved by solving the key hurdles. Orv Hetil. 2017; 158(46): 1819–1830.


2021 ◽  
Vol 32 (6) ◽  
pp. 226-231
Author(s):  
Katie Boog

Side effects are the most common reason for the discontinuation of contraceptive methods. Dr Katie Boog summarises the available evidence on how to manage them Although often transient, side effects are the most common reason for individuals to discontinue contraception. The evidence to prove causality is limited, as is evidence-based guidance on how to manage these side effects. This article summarises the available evidence. For individuals who have new or worsening acne on progestogen-only contraception (POC), switching to combined hormonal contraception (CHC) is likely to improve their skin. Continuous or extended CHC use may be beneficial for individuals with premenstrual mood change, and for those who experience headaches in the hormone-free interval. Unpredictable bleeding patterns on POC are common. Injectable users can try reducing the interval between injections to 10 weeks. Implant, injectable or intrauterine system users can be offered a 3-month trial of a combined oral contraceptive pill (COC). CHC and POP users with unpredictable bleeding may benefit from switching to an alternative preparation.


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