scholarly journals LOCALIZATION AND ONSET OF AMYLASE ACTIVITY IN MOUSE SALIVARY GLANDS DETERMINED BY A SUBSTRATE FILM METHOD

1971 ◽  
Vol 19 (5) ◽  
pp. 310-319 ◽  
Author(s):  
RICHARD J. SMITH ◽  
JACK FROMMER ◽  
ROBERT SCHIFF
Keyword(s):  
Parotid Gland ◽  
Salivary Glands ◽  
Amylase Activity ◽  
Submandibular Glands ◽  
Males And Females ◽  
Starch Substrate ◽  
Convoluted Tubules ◽  
Film Method ◽  
Positive Results ◽  
Substrate Film

A starch substrate film technique was used to determine the localization and onset of amylase activity in the major salivary glands of mice. The earliest activity occurred in the parotid gland of males and females at 8 days of age. The intensity of the reaction rapidly increased so that by day 16 the entire parotid gland was amylase-positive. The submandibular gland exhibited the sexual dimorphism that has been characterized for the adult gland. Amylase activity was observed in the male at 24 days of age, shortly after the first morphologic differences between the submandibular glands of males and females became apparent. The female showed positive results at 36 days of age. Amylase activity in the submandibular glands was localized to the convoluted tubules. As the gland developed, the amylase activity increased in correlation with the increasing concentration of these tubules. The sublingual gland was always amylase-negative.

scholarly journals IS THERE AN EARLY ULTRASONOGRAPHIC PATTERN IN SALIVARY GLANDS IN BOTH PRIMARY AND SECONDARY SJÖGREN SYNDROME?

2017 ◽  
Vol 26 (1) ◽  
pp. 30-37
Author(s):  
Vasilia Iorgoveanu ◽  
◽  
Violeta Bojinca ◽  
Madalina Gheorghe ◽  
Diana Mazilu ◽  
...  
Keyword(s):  
Parotid Gland ◽  
Salivary Glands ◽  
Early Period ◽  
Sjögren Syndrome ◽  
Biological Data ◽  
Inflammatory Disorder ◽  
Sjogren Syndrome ◽  
Parotid Glands ◽  
Submandibular Glands ◽  
Left And Right

Background. Sjögren syndrome (SS) is a systemic chronic inflammatory disorder characterized by lymphocytic infiltrates in exocrine organs. Ultrasonography (US) demonstrates specificity and sensibility in major salivary glands (SG) evaluation. Recent data confirm US might be used as primary evaluation technique for its ability to show structural alterations of parenchyma (1). Objective. To assess the gray scale (GS) parenchymal inhomogeneity of major SG in patients with established primary and secondary SS and correlate with clinical and biological data. Methods. Consecutive patients with SS were recruited and SG US was performed. Inhomogeneity of glandular parenchyma was quantified binary on each gland. ESSDAI and ESSPRI scores were calculated. Statistics was performed with SPSS. Results. Twenty one (42.85% primary SS, 90.47% female) consecutive patients were included. Mean age was 53.66+/-12.99 years and disease duration 5.33+/-3.74 years. Antibody SSA/SSB presence was found in 85.7% (18/21). ESSDAI mean was 8.67+/-8.9 (0-29), ESSPRI 10.13+/-5.59(0-20). There were no differences regarding ESSDAI and ESSPRI in the two groups (primary and secondary SS). Right parotid gland showed alterations in 71.4% patients (77% with primary SS, 66% with secondary SS). Frequently inhomogeneity was found in all major SG (33%, 22% left and right submandibular, 77%, 44.4% left and right parotid glands) in primary SS. Both submandibular glands were symmetrically involved (p<0.02). Duration of disease was negatively correlated to inhomogeneity of right parotid gland (p<0.02). Conclusion. Inhomogeneity in major SG in GS US was found in the majority of patients with primary and secondary SS. The symmetrical involvement of submandibular glands was significant. The inhomogeneity appears in the early period of diagnosis. No major differences were found between two groups.

scholarly journals Kallikrein localization in rodent salivary glands and kidney with the immunoglobulin-enzyme bridge technique.

1979 ◽  
Vol 27 (12) ◽  
pp. 1567-1576 ◽  
Author(s):  
J A Simson ◽  
S S Spicer ◽  
J Chao ◽  
L Grimm ◽  
H S Margolius
Keyword(s):  
Salivary Glands ◽  
Distal Tubule ◽  
Female Rats ◽  
Apical Region ◽  
Submandibular Glands ◽  
Granular Convoluted Tubule ◽  
Duct Cells ◽  
Male And Female Rats ◽  
Rats And Mice ◽  
Convoluted Tubules

Kallikrein has been localized in rodent kidney and salivary glands by means of an immunoglobulin-enzyme bridge technique. In sections of kidney, anti-kallikrein antibodies bound to the apical region of certain distal tubule segments in the cortex, to reabsorption droplets of proximal convoluted tubules, and to certain duct segments in the papilla. In salivary glands of both male and female rats and mice, and apical rim of most striated duct cells of submandibular, parotid and sublingual glands and granular tubules of submandibular glands exhibited immunoreactivity. Granular intercalated duct cells in female submandibular glands also displayed immunostaining for kallikrein. Phenylephrine administration resulted in loss of immunoreactive granules from the granular convoluted tubule cells of male mouse submandibular gland. This response was paralleled by a biochemically demonstrable decrease in kallikrein-like tosylarginine methyl ester (TAME) esterase activity.

scholarly journals Intraductal Carcinoma of the Parotid Gland Presenting as Parapharyngeal Mass

2020 ◽  
Vol 5 (3) ◽  
pp. 1-7
Author(s):  
Yamato Oki ◽  
Hiromitsu Hatakeyama ◽  
Masako Otani ◽  
Hidetaka Ikemiyagi ◽  
Masanori Komatsu ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Parotid Gland ◽  
Salivary Glands ◽  
Parapharyngeal Space ◽  
Malignant Tumors ◽  
Relevant Literature ◽  
Ct Scans ◽  
Intraductal Carcinoma ◽  
First Case

Intraductal carcinomas are rare, malignant tumors that arise from the salivary glands. They commonly grow from the parotid gland and no cases growing from the parapharyngeal space have been reported to date. We report a 76-year-old man who was inadvertently found to have a parapharyngeal lesion by CT scans and MR imaging. The tumor was resected through an upper neck approach and diagnosed histopathologically as intraductal carcinoma. As far as we are aware, this is the first case of intraductal carcinoma arising from the parapharyngeal space. Here, we describe the management of this disease together with a review of the relevant literature.

FUNCTIONAL DISORDERSOF THE SALIVARY GLANDS IN PATIENTS WITH COMPRESSION AND DISLOCATION DYSFUNCTION OF THE TEMPOROMANDIBULAR JOINT AND THEIR CORRECTION

2021 ◽  
Vol 74 (7) ◽  
pp. 1695-1698
Author(s):  
Oleg V. Rybalov ◽  
Pavel I. Yatsenko ◽  
Olga Yu. Andriyanova ◽  
Elena S. Ivanytska ◽  
Maria A. Korostashova
Keyword(s):  
Parotid Gland ◽  
Salivary Glands ◽  
Functional State ◽  
Oral Fluid ◽  
Healthy Individuals ◽  
Parotid Glands ◽  
Posterior Teeth ◽  
Fluid Content ◽  
Lower Jaw ◽  
Before And After

The aim: Is to assess the functional state of parotid glands and general secretion in patients with compression, dislocation dysfunction of TMJ, to correct the revealed disorders. Materials and methods: We examined 46 patients with dysfunction of TMJ. Examination included TMJ zonography and salivary glands sonography. We studied the general and parotid secretion, transparency, viscosity, pH of the oral fluid and the secretions of the parotid glands before and after treatment. The treatment of dysfunction and hyposialosis included the repositioning of the articular heads of the lower jaw in the correct anatomical position, the use of a repositioning plate on the posterior teeth at the compression side of the articular head, bougienage of the duct of the parotid gland, administration of 10% magnesium-mineral solution of bischofite into the gland. Results: In patients with TMJ dysfunction, a significant decrease in the oral fluid content was noted before treatment. The saliva transparency was reduced, the viscosity was increased, the pH was slightly acidic. A study, which was carried out a month after completion of the course of treatment showed that all the studied parameters corresponded to those in healthy individuals. Conclusions: The study confirmed that in compression and dislocation dysfunction of TMJ, there are disorders of the functional state of the salivary glands.

l-THYROXINE, CORTISOL AND DIET AFFECT THE LEVEL OF AMYLASE IN THE PAROTID GLAND OF DEVELOPING RATS

1980 ◽  
Vol 87 (1) ◽  
pp. 65-71 ◽  
Author(s):  
MASAYOSHI KUMEGAWA ◽  
NORIHIKO MAEDA ◽  
TOSHIHIKO YAJIMA ◽  
TAISHIN TAKUMA ◽  
EIKO IKEDA ◽  
...  
Keyword(s):  
Body Weight ◽  
Enzyme Activity ◽  
Parotid Gland ◽  
Amylase Activity ◽  
Synergistic Effects ◽  
Dietary Factors ◽  
Adult Rats ◽  
Early Increase ◽  
Adrenalectomized Rats ◽  
Intact Rats

The effects of cortisol (10 μg/g body weight) and l-thyroxine (T4; 0·2 μg/g body weight) on the activity of parotid gland amylase in young rats were investigated. Administration of cortisol or T4 for 5 consecutive days from day 5 after birth caused the precocious appearance of amylase, T4 having almost twice the effect of cortisol. Cortisol and T4 did not have synergistic effects. In thyroidectomized-adrenalectomized rats, T4 increased amylase activity but cortisol did not. The increase in enzyme activity after day 20 was much less in rats thyroidectomized on day 10 than in rats adrenalectomized on day 10. These results suggest that T4 has a direct effect on the early increase of amylase activity (days 15–25) and that the action of glucocorticoid requires the presence of endogenous thyroid hormones. The hormone-induced level of amylase in intact rats was less than that of normal adult rats. Forced weaning of intact rats resulted in a further increase in amylase activity, suggesting that further amylase accumulation (after day 25) may be due to dietary factors.

Terminal duct adenocarcinomas of the parotid gland

1995 ◽  
Vol 109 (5) ◽  
pp. 466-468 ◽  
Author(s):  
Bonnie L. Kemp ◽  
John G. Batsakis ◽  
Adel K. El-Naggar ◽  
Sophia N. Kotliar ◽  
Mario A. Luna
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Salivary Glands ◽  
Minor Salivary Gland ◽  
Low Grade ◽  
Minor Salivary Glands ◽  
Biological Behaviour ◽  
Parotid Neoplasms ◽  
Clinicopathological Study

AbstractThe major salivary glands are considered to rarely be the sites of primary terminal duct adenocarcinomas, a neoplasm with a considerable predilection for origin from intraoral minor salivary glands. We present a clinicopathological study of 22 terminal duct adenocarcinomas of the parotid gland, the largest single series to date. A comparison between the parotid neoplasms and over 200 minor salivary gland terminal duct adenocarcinomas indicates there is little difference in biological behaviour and confirms the low-grade quality of the carcinomas, regardless of site of origin.

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