Rescue of Acute Refractory Hypercapnia and Acidosis Secondary to Life-Threatening Asthma with Extracorporeal Carbon Dioxide Removal (ECCO2R)

2011 ◽  
Vol 12 (2) ◽  
pp. 140-142 ◽  
Author(s):  
Steven Lobaz ◽  
Michelle Carey
Keyword(s):  
Carbon Dioxide ◽  
Carbon Dioxide Removal ◽  
Extracorporeal Carbon Dioxide Removal ◽  
Life Threatening

scholarly journals Extracorporeal carbon dioxide removal as a bridge to lung transplantation in life-threatening hypercapnia

Critical Care ◽  
2014 ◽  
Vol 18 (Suppl 1) ◽  
pp. P307
Author(s):  
K Riss ◽  
T Staudinger ◽  
R Ullrich ◽  
GG Krenn ◽  
C Sitzwohl ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Lung Transplantation ◽  
Carbon Dioxide Removal ◽  
Extracorporeal Carbon Dioxide Removal ◽  
Life Threatening

Pumpless extracorporeal carbon dioxide removal for life-threatening asthma

2007 ◽  
Vol 35 (3) ◽  
pp. 945-948 ◽  
Author(s):  
Stuart C. Elliot ◽  
Kumar Paramasivam ◽  
John Oram ◽  
Andrew R. Bodenham ◽  
Simon J. Howell ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Carbon Dioxide Removal ◽  
Extracorporeal Carbon Dioxide Removal ◽  
Life Threatening

scholarly journals A Proof of Concept Study, Demonstrating Extracorporeal Carbon Dioxide Removal Using Hemodialysis with a Low Bicarbonate Dialysate

ASAIO Journal ◽  
2019 ◽  
Vol 65 (6) ◽  
pp. 605-613 ◽  
Author(s):  
Matthew E. Cove ◽  
Lien Hong Vu ◽  
Troels Ring ◽  
Alexandra G. May ◽  
William J. Federspiel ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Carbon Dioxide Removal ◽  
Proof Of Concept ◽  
Extracorporeal Carbon Dioxide Removal ◽  
Concept Study

Extracorporeal carbon dioxide removal or ECCO2R

2017 ◽  
pp. 197-203
Author(s):  
Alain Vuylsteke ◽  
Daniel Brodie ◽  
Alain Combes ◽  
Jo-anne Fowles ◽  
Giles Peek
Keyword(s):  
Carbon Dioxide ◽  
Carbon Dioxide Removal ◽  
Extracorporeal Carbon Dioxide Removal

Carbon dioxide removal using low bicarbonate dialysis in rodents

Perfusion ◽  
2019 ◽  
Vol 34 (7) ◽  
pp. 578-583 ◽  
Author(s):  
Lien H Vu ◽  
John A Kellum ◽  
William J Federspiel ◽  
Matthew E Cove
Keyword(s):  
Carbon Dioxide ◽  
In Vitro Study ◽  
Blood Gases ◽  
Carbon Dioxide Removal ◽  
Low Flow ◽  
Sprague Dawley ◽  
Bicarbonate Concentration ◽  
Extracorporeal Carbon Dioxide Removal ◽  
Arterial Ph

Background: Extracorporeal carbon dioxide removal may be used to manage hypercapnia, but compared to dialysis, it’s not widely available. A recent in vitro study showed that dialysis with low bicarbonate dialysates removes CO2. Objective: To show that bicarbonate dialysis removes CO2 in an animal model to validate in-vitro findings and quantify the effect on arterial pH. Methods: Male Sprague-Dawley hypercapnic rats were dialyzed with either a conventional dialysate (PrismasolTM) or a bicarbonate-free dialysate (Bicarb0). The effect of dialysis on standard blood gases and electrolytes was measured. Results: Partial pressure of CO2 and bicarbonate concentration in blood decreased significantly after exposure to Bicarb0 compared to PrismasolTM (filter outflow values 12.8 vs 81.1 mmHg; p < 0.01 for CO2 and 3.5 vs 22.0 mmol/L; p < 0.01 for bicarbonate). Total CO2 content of blood was reduced by 459 mL/L during dialysis with Bicarb0 (filter inflow 546 ± 91 vs filter outflow 87 ± 52 mL/L; p < 0.01), but was not significantly reduced with PrismasolTM. Conclusions: Bicarbonate dialysis removes CO2 at rates comparable to existing low-flow ECCO2R.

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