scholarly journals Treatments for Adolescents With Comorbid ADHD and Substance Use Disorder: A Systematic Review

2015 ◽  
Vol 24 (9) ◽  
pp. 1215-1226 ◽  
Author(s):  
Michelle J. Zaso ◽  
Aesoon Park ◽  
Kevin M. Antshel
Keyword(s):  
Systematic Review ◽  
Substance Use ◽  
Substance Use Disorder ◽  
Pharmacological Intervention ◽  
Psychotherapeutic Interventions ◽  
Effective Interventions ◽  
Potential Efficacy ◽  
Treatment Gains ◽  
Comorbid Adhd

Objective: Comorbid ADHD and substance use disorder (SUD) presents frequently in adolescence, a developmental period that may promote the emergence of substance misuse among individuals with ADHD. Comorbid ADHD and SUD in adolescence results in significant and unique treatment challenges, necessitating examination into effective interventions. Method: This systematic review examined existing research into the treatment of comorbid adolescent ADHD and SUD. Results: Findings from a small number of pharmacological intervention studies suggest potential efficacy of extended-release stimulant and nonstimulant medications. Efficacy of psychotherapeutic interventions has not been systematically examined. Conclusion: Current research on treatments for comorbid ADHD and SUD in adolescence is limited. Future placebo-controlled clinical trials using large samples are needed to examine the efficacy of psychotherapeutic interventions, the heightened risk of prescription stimulant misuse, and the long-term maintenance of treatment gains in this population. Clinical guidelines for the treatment of comorbid ADHD and SUD are discussed.

Try to Remember: Interplay between Memory and Substance Use Disorder

2018 ◽  
Vol 20 (2) ◽  
pp. 158-165 ◽  
Author(s):  
Rashidi Mohamed Pakri Mohamed ◽  
Jaya Kumar ◽  
Ernie Yap ◽  
Isa Naina Mohamed ◽  
Hatta Sidi ◽  
...  
Keyword(s):  
Substance Use ◽  
Substance Use Disorder ◽  
Pharmacological Intervention ◽  
Long Term Memory ◽  
Potential Candidate ◽  
Learning Disorder ◽  
Inhibitory Peptide ◽  
Term Memory ◽  
Biochemical Mechanisms

Memories associated with substance use disorders, or substance-associated cues increase the likelihood of craving and relapse during abstinence. There is a growing consensus that manipulation of synaptic plasticity may reduce the strength of substance abuse-related memories. On the biological front, there are new insights that suggest memories associated with substance use disorder may follow unique neurobiological pathways that render them more accessible to pharmacological intervention. In parallel to this, research in neurochemistry has identified several potential candidate molecules that could influence the formation and maintenance of long-term memory. Drugs that target these molecules (blebbistatin, isradipine and zeta inhibitory peptide) have shown promise at the preclinical stage. In this review, we shall provide an overview of the evolving understanding on the biochemical mechanisms involved in memory formation and expound on the premise that substance use disorder is a learning disorder.

scholarly journals Psychosocial factors associated with coping behaviour after inpatient treatment for substance use disorder: a systematic review study protocol

BMJ Open ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. e022673 ◽  
Author(s):  
Dagny Adriaenssen Johannessen ◽  
Trond Nordfjærn ◽  
Amy Østertun Geirdal
Keyword(s):  
Systematic Review ◽  
Substance Use ◽  
Psychosocial Factors ◽  
Substance Use Disorder ◽  
Inpatient Treatment ◽  
Cochrane Library ◽  
Stressful Situation ◽  
Coping Behaviour ◽  
Factors Associated

IntroductionMuch is known about factors associated with coping with abstinence from substance use. The planned systematic review aims to summarise available studies exploring the change in psychosocial factors associated with coping after long-term (≥3 months) inpatient treatment for substance use disorder (SUD). Examples ofpsychosocial factorsof interest are social support, housing, activity (eg, employment and education) mental health and quality of life.Coping behaviourcan be understood as responses or actions taken in a stressful situation, particularly how psychosocial factors affect a person’s coping behaviour with abstinence from substances in everyday life (characterised as a stressful situation).Methods and analysisA set of text words were developed based on the population (people with SUD), exposure (long-term inpatient SUD treatment), outcome (psychosocial factors) and study design (prospective cohort studies) of interest. A systematic search will be conducted in eight electronic databases: Campbell Collaboration Library, Cochrane Library, EMBASE, Epistemonikos, Medline, PsychINFO, Social Sciences Citation Index and SocINDEX. The titles and abstracts will be screened for relevance before a pre-piloted data collection form will be used to evaluate eligibility and extract data from the search results. The planned review will include peer-reviewed study reports published in English or Scandinavian language.Ethics and disseminationThe target group, people with SUD, might be considered as vulnerable. Based on this, the population will be the group of interest in the planned systematic review of studies that have already been conducted. Patients and the general public will not be involved in the development of this systematic review. The results will be summarised in a study report and submitted to a peer-reviewed international journal. Additionally, results will be disseminated in the mass media and at international research conferences.PROSPERO registration numberCRD42018087408.

Predicting attrition in long-term residential substance use disorder treatment: A modifiable risk factors perspective.

2020 ◽  
Vol 17 (4) ◽  
pp. 472-482
Author(s):  
Danielle E. Baker ◽  
Keith A. Edmonds ◽  
Maegan L. Calvert ◽  
Sarah M. Sanders ◽  
Ana J. Bridges ◽  
...  
Keyword(s):  
Risk Factors ◽  
Substance Use ◽  
Substance Use Disorder ◽  
Modifiable Risk Factors ◽  
Substance Use Disorder Treatment ◽  
Disorder Treatment

scholarly journals Recovery-informed Theory: Situating the Subjective in the Science of Substance Use Disorder Recovery

2019 ◽  
Vol 1 (3) ◽  
pp. 1-15 ◽  
Author(s):  
Austin M Brown ◽  
Robert D Ashford
Keyword(s):  
Substance Use ◽  
Substance Use Disorders ◽  
Substance Use Disorder ◽  
Systems Of Care ◽  
Grand Theory ◽  
Recovery Strategies ◽  
Recovery Capital ◽  
New Ideas

As recovery from substance use disorder becomes more than a mere quantifiable outcome, there exists a need to discuss and propose the underlying theoretical constructs that ultimately describe and identify the science of recovery. In this abstract undertaking, we propose an initial formulation of a grand theory of recovery science, built upon the seminal theories of recovery capital, recovery-oriented systems of care, and socioecological theory. This grand theory - labeled recovery-informed theory (RIT) - states that successful long-term recovery is self-evident and is a fundamentally emancipatory set of processes. This paper will discuss, analyze, and explore this theory as it is situated within the larger substance use, misuse, and disorder contexts. The uses, implications, and benefits of RIT as an organizing point of inquiry for recovery science are also discussed. By promoting the role of subjective recovery experience in the formulation of the study of recovery, it may be possible to summon new ideas, metrics, and strategies that can directly address substance use disorders in society. Adopting a recovery-informed understanding as follows from this grand theory may allow individual recovery and wellness trajectories to be explored, adapted, and modified to exemplify person-centered and individualized recovery strategies.

scholarly journals Long-term clinical effectiveness of lithium maintenance treatment in types I and II bipolar disorders

2001 ◽  
Vol 178 (S41) ◽  
pp. s184-s190 ◽  
Author(s):  
Leonardo Tondo ◽  
Ross J. Baldessarini ◽  
Gianfranco Floris
Keyword(s):  
Substance Use ◽  
Substance Use Disorder ◽  
Lithium Treatment ◽  
Bipolar Disorders ◽  
Clinical Effectiveness ◽  
Type I ◽  
Rapid Cycling ◽  
Single Episode ◽  
Episode Frequency

BackgroundThe effectiveness of lithium is being questioned increasingly and requires clarification.AimsTo assess the effectiveness of lithium treatment in depression and mania, syndromal types I and II, with predominantly mixed or psychotic episodes or rapid cycling, during treatment resumed following discontinuation, and across three decades.MethodThe longitudinal course of 360 patients with bipolar disorder compliant with lithium treatment for at least 1 year and without comorbidity for substance use disorder was reviewed.ResultsRisk of single-episode recurrences, a common index of treatment failure, was similar to that in other reports. Both episode frequency and ‘time ill’ improved more in type II than type I cases. Reduced morbidity during treatment was similar in patients with mixed or psychotic episodes, or rapid cycling, and in less complex cases. Retreatment yielded minor decrements in response, and there was no tendency for lesser responses in more recent years.ConclusionsBased on overall affective morbidity, long-term lithium treatment in compliant patients without comorbid substance use disorder, though imperfect, remains effective, even in subgroups of supposedly poor prognosis.

Substance Use Disorder Treatments

2017 ◽  
pp. 96-118 ◽  
Author(s):  
Liliane Cambraia Windsor ◽  
Douglas C. Smith ◽  
Kyle M. Bennett ◽  
Frederick X. Gibbons
Keyword(s):  
Substance Use ◽  
Emerging Adults ◽  
Substance Use Disorder ◽  
The United States ◽  
Drug Misuse ◽  
Future Research ◽  
Cultural Groups ◽  
Treatment Access ◽  
Effective Interventions ◽  
Diverse Groups

Today’s emerging adults belong to one of the most diverse generations in the United States and show the highest rates of alcohol and illicit drug misuse, facing significant health risks. Thus it is critical to develop effective interventions to reduce alcohol and illicit substance misuse and its related harms among this diverse group. This chapter examines the current literature on the development and effectiveness of existing culturally relevant substance use disorder treatments and makes recommendations for future research and best practices. We argue that given their unique needs, the severity of their substance use, and the low rates of treatment engagement among this population, it is critical that treatment efforts focus on increasing effective treatment access to all emerging adults. We further encourage substance use disorder treatment researchers and practitioners to move beyond addressing culture-bound intervention targets focused on specific cultural groups. The chapter advocates for the development, testing, and adoption of interventions that are responsive to cultural contexts and that (1) target social determinants of health, (2) are equally effective with privileged and marginalized emerging adults, and (3) prepare therapists to effectively deliver interventions to diverse groups and demonstrate cultural competence.

Insight in substance use disorder: A systematic review of the literature

2020 ◽  
Vol 111 ◽  
pp. 106549
Author(s):  
Dayle Raftery ◽  
Peter J. Kelly ◽  
Frank P. Deane ◽  
Amanda L. Baker ◽  
Isabella Ingram ◽  
...  
Keyword(s):  
Systematic Review ◽  
Substance Use ◽  
Substance Use Disorder ◽  
Review Of The Literature
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