Long-Term Developmental Outcomes of Prenatal Cocaine Exposure

1999 ◽  
Vol 17 (4) ◽  
pp. 343-353 ◽  
Author(s):  
LeAdelle Phelps ◽  
Jerome William Cottone
Keyword(s):  
Developmental Outcomes ◽  
Cocaine Exposure ◽  
Prenatal Cocaine Exposure ◽  
Prenatal Cocaine

scholarly journals Prenatal Cocaine Exposure and Cardiometabolic Disease Risk Factors in 18 to 20 Year Old African Americans

2015 ◽  
Vol 25 (4) ◽  
pp. 419
Author(s):  
Sarah E. Messiah ◽  
David A. Ludwig ◽  
Denise C. Vidot ◽  
Veronica H. Accornero ◽  
Steven E. Lipshultz ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Disease ◽  
Disease Risk ◽  
Cardiometabolic Disease ◽  
Cocaine Exposure ◽  
Prenatal Cocaine Exposure ◽  
The Metabolic Syndrome ◽  
Prenatal Cocaine ◽  
Cardiometabolic Disease Risk

<p class="Pa7"><strong>Objective: </strong>The long-term effects of prenatal cocaine exposure (PCE) on physical health are largely unknown. No human studies support or refute a relationship between PCE and the long-term risk for cardiovascu­lar and/or metabolic disease. We investi­gated the association of PCE on primary car­diometabolic disease risk factors in African Americans (AA) aged 18 to 20 years.</p><p class="Pa7"><strong>Design: </strong>Cohort, longitudinal, prospective.</p><p class="Pa7"><strong>Setting: </strong>Miami-Dade County, Florida, and the University of Miami Miller School of Medicine/Jackson Memorial Medical Center.</p><p class="Pa7"><strong>Participants: </strong>Healthy full-term inner-city AA adolescents (aged 18 to 20 years, <em>N</em>=350) previously enrolled at birth from 1990-1993.</p><p class="Pa7"><strong>Main Outcome Measures: </strong>Fasting serum insulin, glucose, lipids, and high-sensitivity C-reactive protein; systolic and diastolic blood pressures; and the components and prevalence of the metabolic syndrome.</p><p class="Pa7"><strong>Results: </strong>There were no PCE-associated differences in cardiometabolic disease risk factors including the metabolic syndrome and its individual components in AAs aged 18 to 20 years.</p><p><strong>Conclusions: </strong>The results of our study do not support an association between PCE and increased cardiometabolic disease risk in AAs aged 18 to 20 years. Whether PCE is associated with cardiovascular or metabolic disease in adulthood would require further investigation. <em>Ethn Dis. </em>2015;25(4):419- 426; doi:10.18865/ed.25.4.419</p><strong></strong>

Prenatal Cocaine Exposure Produces Long-Term Impairments in Brain Serotonin Function in Rat Offspringa

1998 ◽  
Vol 846 (1) ◽  
pp. 355-357 ◽  
Author(s):  
GEORGE BATTAGLIA ◽  
THERESA M. CABRERA-VERA ◽  
LOUIS D. VAN DE KAR ◽  
FRANCISCA GARCIA ◽  
ALEKSANDRA VICENTIC ◽  
...  
Keyword(s):  
Brain Serotonin ◽  
Cocaine Exposure ◽  
Prenatal Cocaine Exposure ◽  
Prenatal Cocaine
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