The course of hematocrit value along the length of a dialyzer’s fiber: Hemoconcentration modeling and validation methods

2019 ◽  
Vol 42 (9) ◽  
pp. 482-489
Author(s):  
Ali Poorkhalil ◽  
Foivos Mouzakis ◽  
Ali Kashefi ◽  
Khosrow Mottaghy
Keyword(s):  
Experimental Data ◽  
Driving Forces ◽  
Semiempirical Model ◽  
Sequential Order ◽  
Filtration Process ◽  
Operational Conditions ◽  
Wide Range ◽  
Hemodynamic Characteristics ◽  
Good Agreement

Objectives:Contemporary therapies for chronic kidney disease patients encompass a wide range of hemodialysis treatments, most of which rely greatly on dialyzers and hemofilters. The filtration process taking place in these devices with respect to the hemodynamic characteristics of the flow, has not yet been fully investigated. This study aims at improving the understanding of hemodynamics in a dialyzer by employing experimental methods and mathematical models.Methods:A semiempirical model has been formulated based on the principles of hemodynamics, considering the dominant phenomena of filtration-backfiltration and the corresponding driving forces. An in vitro hemodialysis circuit was accordingly assembled for experimental data acquisition, and subsequently for model validation. The circuit consisted of two dialyzers arranged in sequential order, in pursuance of increasing the number of sampling points. Fresh, heparinized porcine blood was used throughout the course of this study. Pressure and flow data obtained from in vitro investigations with the hemodialysis circuit were used as an input for the semiempirical model.Findings:The model predicted a substantial divergence in the course of hematocrit value along the length of the hollow fibers, which is corroborated by the experimental data. Particularly in certain operational conditions, hematocrit rose from 25% at the inlet to 65% halfway along the dialyzers’ length, to end at 30% at the outlet.Conclusion:Validation of the model’s predictions with experimental data demonstrated a very good agreement, confirming the model’s accuracy. Potential implementation of the model in clinical practice in the future might contribute greatly to an improved hemodialysis experience.

Combustion Simulation of Propane/Oxygen (With Nitrogen/Argon) Mixtures Using Rate-Controlled Constrained-Equilibrium

2018 ◽  
Vol 141 (2) ◽  
Author(s):  
Guangying Yu ◽  
Hameed Metghalchi ◽  
Omid Askari ◽  
Ziyu Wang
Keyword(s):  
Experimental Data ◽  
Energy System ◽  
Kinetic Mechanism ◽  
Chemical Kinetic ◽  
Oxygen Mixture ◽  
Free Valence ◽  
Wide Range ◽  
Constrained Equilibrium ◽  
Rate Controlled ◽  
Good Agreement

The rate-controlled constrained-equilibrium (RCCE), a model order reduction method, has been further developed to simulate the combustion of propane/oxygen mixture diluted with nitrogen or argon. The RCCE method assumes that the nonequilibrium states of a system can be described by a sequence of constrained-equilibrium states subject to a small number of constraints. The developed new RCCE approach is applied to the oxidation of propane in a constant volume, constant internal energy system over a wide range of initial temperatures and pressures. The USC-Mech II (109 species and 781 reactions, without nitrogen chemistry) is chosen as chemical kinetic mechanism for propane oxidation for both detailed kinetic model (DKM) and RCCE method. The derivation for constraints of propane/oxygen mixture starts from the eight universal constraints for carbon-fuel oxidation. The universal constraints are the elements (C, H, O), number of moles, free valence, free oxygen, fuel, and fuel radicals. The full set of constraints contains eight universal constraints and seven additional constraints. The results of RCCE method are compared with the results of DKM to verify the effectiveness of constraints and the efficiency of RCCE. The RCCE results show good agreement with DKM results under different initial temperature and pressures, and RCCE also reduces at least 60% CPU time. Further validation is made by comparing the experimental data; RCCE shows good agreement with shock tube experimental data.

MAGNETIC BODY FORCE

2005 ◽  
Vol 19 (07n09) ◽  
pp. 1205-1208 ◽  
Author(s):  
A. F. BAKUZIS ◽  
KEZHENG CHEN ◽  
WEILI LUO ◽  
HONGZHANG ZHUANG
Keyword(s):  
Experimental Data ◽  
Magnetic Fluid ◽  
Magnetic Force ◽  
Body Force ◽  
Wide Range ◽  
Magnetic Body Force ◽  
Good Agreement

We have studied magnetic force on sperical magnetic fluid samples with a wide range of concentrations by pendulum method. The results demonstrate good agreement with Kelvin body force and show that other force expressions clearly deviate from experimental data for large sussceptibility values.

scholarly journals The Formation of Deposits on the Walls of the Pores in the Filtering Process

2019 ◽  
Vol 14 (2) ◽  
pp. 15-22
Author(s):  
Yu. A. Taran ◽  
A. V. Kozlov ◽  
A. L. Taran
Keyword(s):  
Experimental Data ◽  
Pressure Drop ◽  
Driving Force ◽  
Nonequilibrium Thermodynamics ◽  
Driving Forces ◽  
Solid Particles ◽  
Original Structure ◽  
Small Particles ◽  
Filtration Process ◽  
Filter Unit

The aim of the work is to consider the mechanism of clogging the pores of the filter unit by small particles from the flow of filtrate inside them. Theoretical ideas about the process of filtering with the deposition of small particles from the filtrate on the pore walls and attribution of its fundamentals to restructuring from the original structure to the final structure allow to describe the process of clogging the pores using well studied concepts of known processes with phase transformations (in particular, crystallization). Based on this analogy and the approach to the description of the transformation of the "old" structure into a "new" one in time, using experimental data and their processing we calculated the rate of nucleation of the sediment centers (ωnucl), the linear (υlin) and volumetric rates of sediment plaques growth in the pores of the filter unit at different values of the process driving force, at different pressure difference in the system, and at different concentrations of solid particles in the suspension. Interpolation and extrapolation dependences were obtained for analyzing the mechanisms of sediments formation and growth for determining and calculating these (ωnucl, υlin) rates. Using the concepts of nonequilibrium thermodynamics to assess the influence of the driving forces we studied their influence (changes in the concentration of solid particles in the filtrate suspension and pressure drop across the filtering layer) on the dynamics of the filtration process. Using the data obtained it is possible to find the degree of clogging of through pores, which determines the filtration conditions, the filter septum type, and the filter overall dimensions.

Power–gap relationships in low consistency refining

2019 ◽  
Vol 34 (1) ◽  
pp. 36-45 ◽  
Author(s):  
Jorge Enrique Rubiano Berna ◽  
Mark Martinez ◽  
James Olson
Keyword(s):  
Experimental Data ◽  
Force Sensor ◽  
Pilot Scale ◽  
Mill Scale ◽  
Control Power ◽  
Wide Range ◽  
Theoretical Assumptions ◽  
Mechanical Pulps ◽  
The Relationship ◽  
Good Agreement

Abstract Distance between stationary and rotating refining plates, gap, has a direct and significant impact on refining power. Gap is almost universally used to control power in low consistency refining operations. The relationship between power and gap are affected by refiner size, pulp type, plate pattern and refining conditions. In this study, a correlation was developed to describe the power–gap relationships at a wide range of refining conditions and furnish. The correlation was developed using pilot-scale refining data of mechanical pulps. Results showed that a properly defined dimensionless power number is suitable to describe refining power as well as to compare different refiners under the same grounds. The developed correlation was also used to predict mill-scale refining data showing good agreement with between predicted and measured values. Finally, experimental data from force sensor measurements supports the correlation’s theoretical assumptions.

On the Minimum Film Boiling Conditions for Spherical Geometries

1980 ◽  
Vol 102 (2) ◽  
pp. 335-341 ◽  
Author(s):  
F. S. Gunnerson ◽  
A. W. Cronenberg
Keyword(s):  
Experimental Data ◽  
Heat Flux ◽  
Flat Plate ◽  
Analytical Method ◽  
Boiling Point ◽  
Film Boiling ◽  
Heater Surface ◽  
Wide Range ◽  
Minimum Heat ◽  
Good Agreement

An analytical method is presented for predicting the minimum heater temperature and the minimum heat flux at the onset of film boiling for spherical and flat plate heaters in saturated and subcooled liquids. Consideration is given to a variety of factors known to affect the minimum film boiling point, including transient liquid-heater contact, interfacial wettability, heater geometry, and liquid subcooling. The theoretical correlations developed are the first known predictions for spherical geometries. A comparison of theory with experimental data indicates good agreement for the minimum heat flux and the minimum film boiling temperature. Results indicate that the minimum conditions may span a wide range depending upon the thermophysical nature of the heater surface and the boiling liquid.

VLE Determination of Carbon Dioxide Loaded Aqueous Alkanolamine Mixtures Using Modified Kent Eisenberg Model

2017 ◽  
Vol 231 (11-12) ◽  
Author(s):  
Humbul Suleman ◽  
Abdulhalim Shah Maulud ◽  
Zakaria Man
Keyword(s):  
Experimental Data ◽  
Carbon Dioxide ◽  
Model Parameters ◽  
Thermodynamic Models ◽  
Carbon Dioxide Absorption ◽  
Proposed Model ◽  
Wide Range ◽  
Experimental Values ◽  
Good Agreement

AbstractA computationally simple thermodynamic framework has been presented to correlate the vapour-liquid equilibria of carbon dioxide absorption in five representative types of alkanolamine mixtures. The proposed model is an extension of modified Kent Eisenberg model for the carbon dioxide loaded aqueous alkanolamine mixtures. The model parameters are regressed on a large experimental data pool of carbon dioxide solubility in aqueous alkanolamine mixtures. The model is applicable to a wide range of temperature (298–393 K), pressure (0.1–6000 kPa) and alkanolamine concentration (0.3–5 M). The correlated results are compared to the experimental values and found to be in good agreement with the average deviations ranging between 6% and 20%. The model results are comparable to other thermodynamic models.

scholarly journals CALCULATION OF PRESSURE DROP IN NARROW ROTATING ANNULAR CLEARANCES

2008 ◽  
Vol 7 (2) ◽  
pp. 27
Author(s):  
C. Y. Nakashima ◽  
S. Oliveira Jr ◽  
E. F. Caetano
Keyword(s):  
Experimental Data ◽  
Pressure Drop ◽  
Flow Regimes ◽  
Volumetric Efficiency ◽  
Taylor Vortex ◽  
General Correlation ◽  
Operational Conditions ◽  
Twin Screw ◽  
Annular Clearance ◽  
Good Agreement

This paper presents a review of correlations used for pressure drop calculation in narrow annular clearances with rotation of inner cylinder. Based on these review, a new general correlation is proposed to calculate pressure drop through such clearances. Results are compared with experimental data for different flow regimes: laminar, laminar with Taylor vortex, smooth and rough turbulent, with good agreement. The main objective is to develop a simple and general correlation that could be used for backflow calculation in twin-screw multiphase pumps. In this kind of pump, the volumetric efficiency is defined mainly by the backflow rate which occurs in the annular clearance between screw and casing. Usually, the backflow is calculated ignoring the influence of shaft rotation over pressure drop and does not consider the several possible flow regimes. Depending on operational conditions, this simplification can lead to significant errors.

Establishment of a High Quality Database for the Acoustic Modeling of Perforated Liners

2011 ◽  
Vol 133 (9) ◽  
Author(s):  
Claus Lahiri ◽  
Lars Enghardt ◽  
Friedrich Bake ◽  
Sermed Sadig ◽  
Miklós Gerendás
Keyword(s):  
Experimental Data ◽  
Acoustic Modeling ◽  
Acoustic Model ◽  
Acoustic Parameters ◽  
High Quality ◽  
Wide Range ◽  
Bias Flow ◽  
Acoustic Instabilities ◽  
Parameter Influence ◽  
Good Agreement

Perforated liners, especially in combination with a bias flow, are very effective sound absorbers. When appplied to gas turbine combustors, they can suppress thermo-acoustic instabilities and thus allow the application of new combustion concepts concerning higher efficiency and lower emissions. While the successful application of such a damping concept has been shown, it is still not possible to accurately predict the damping performance of a given configuration. This paper provides a comprehensive database of high quality experimental data. Variations of geometric, fluid mechanic, and acoustic parameters have been studied, including realistic engine configurations. The results demonstrate each parameter influence on the damping performance. A low order thermo-acoustic model is used to simulate the test configurations numerically. The model shows a good agreement with the measurements for a wide range of geometries and Strouhal and bias flow Mach numbers.

scholarly journals Simulation of laser ablation of metals for nanoparticles production

2016 ◽  
Vol 41 ◽  
pp. 1660143 ◽  
Author(s):  
R. V. Davydov ◽  
V. I. Antonov ◽  
T. I. Davydova
Keyword(s):  
Experimental Data ◽  
Laser Ablation ◽  
Femtosecond Laser Ablation ◽  
Hydrodynamic Equations ◽  
Temperature Model ◽  
Wide Range ◽  
Simulation Results ◽  
Range Equation ◽  
Two Temperature ◽  
Good Agreement

In this paper a mathematical model for femtosecond laser ablation of metals is proposed, based on standard two-temperature model connected with 1D hydrodynamic equations. Wide-range equation of state has been developed. The simulation results are compared with experimental data for aluminium and copper. A good agreement for both metals with numerical results and experiment shows that this model can be employed for choosing laser parameters to better accuracy in nanoparticles production by ablation of metals.

Correction for Streamline Curvature and Coriolis Force in a Boundary Layer Integral Method

1981 ◽  
Author(s):  
R. A. Van Den Braembussche ◽  
P. Zunino
Keyword(s):  
Experimental Data ◽  
Integral Method ◽  
Theoretical Calculations ◽  
Correction Term ◽  
Dissipation Factor ◽  
Coriolis Forces ◽  
Streamline Curvature ◽  
Rotation Numbers ◽  
Wide Range ◽  
Good Agreement

The influence of Coriolis forces and streamwise curvature on boundary layers has been introduced into an integral method by adding a correction term to the dissipation factor. This correction term is related to Coriolis forces and streamline curvature in terms of a parameter 13 which was determined using existing experimental data. Theoretical calculations using this value of show good agreement with experimental results for a wide range of curvature and rotation numbers representing realistic conditions for turbomachinery applications.

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