Migraine classification using somatosensory evoked potentials

Cephalalgia ◽  
2019 ◽  
Vol 39 (9) ◽  
pp. 1143-1155 ◽  
Author(s):  
Bingzhao Zhu ◽  
Gianluca Coppola ◽  
Mahsa Shoaran
Keyword(s):  
Machine Learning ◽  
Feature Selection ◽  
Evoked Potentials ◽  
Healthy Volunteers ◽  
Somatosensory Evoked Potentials ◽  
Evoked Potential ◽  
Machine Learning Algorithms ◽  
Somatosensory Evoked Potential ◽  
Support Vector ◽  
Extreme Gradient Boosting

Objective The automatic detection of migraine states using electrophysiological recordings may play a key role in migraine diagnosis and early treatment. Migraineurs are characterized by a deficit of habituation in cortical information processing, causing abnormal changes of somatosensory evoked potentials. Here, we propose a machine learning approach to utilize somatosensory evoked potential-based biomarkers for migraine classification in a noninvasive setting. Methods Forty-two migraine patients, including 29 interictal and 13 ictal, were recruited and compared with 15 healthy volunteers of similar age and gender distribution. The right median nerve somatosensory evoked potentials were collected from all subjects. State-of-the-art machine learning algorithms including random forest, extreme gradient-boosting trees, support vector machines, K-nearest neighbors, multilayer perceptron, linear discriminant analysis, and logistic regression were used for classification and were built upon somatosensory evoked potential features in time and frequency domains. A feature selection method was employed to assess the contribution of features and compare it with previous clinical findings, and to build an optimal feature set by removing redundant features. Results Using a set of relevant features and different machine learning models, accuracies ranging from 51.2% to 72.4% were achieved for the healthy volunteers-ictal-interictal classification task. Following model and feature selection, we successfully separated the three groups of subjects with an accuracy of 89.7% for the healthy volunteers-ictal, 88.7% for healthy volunteers-interictal, 80.2% for ictal-interictal, and 73.3% for healthy volunteers-ictal-interictal classification tasks, respectively. Conclusion Our proposed model suggests the potential use of somatosensory evoked potentials as a prominent and reliable signal in migraine classification. This non-invasive somatosensory evoked potential-based classification system offers the potential to reliably separate migraine patients in ictal and interictal states from healthy controls.

scholarly journals Techniques for Detecting Malware Traffic: A Comprehensive Approach to Feature Selection and Classification

2021 ◽  
Vol 9 (12) ◽  
pp. 1-10
Author(s):  
Harsha A K
Keyword(s):  
Machine Learning ◽  
Feature Selection ◽  
Random Forest ◽  
Learning Algorithms ◽  
Malware Detection ◽  
Machine Learning Algorithms ◽  
Gradient Boosting ◽  
Support Vector ◽  
Steady Increase ◽  
Extreme Gradient Boosting

Abstract: Since the advent of encryption, there has been a steady increase in malware being transmitted over encrypted networks. Traditional approaches to detect malware like packet content analysis are inefficient in dealing with encrypted data. In the absence of actual packet contents, we can make use of other features like packet size, arrival time, source and destination addresses and other such metadata to detect malware. Such information can be used to train machine learning classifiers in order to classify malicious and benign packets. In this paper, we offer an efficient malware detection approach using classification algorithms in machine learning such as support vector machine, random forest and extreme gradient boosting. We employ an extensive feature selection process to reduce the dimensionality of the chosen dataset. The dataset is then split into training and testing sets. Machine learning algorithms are trained using the training set. These models are then evaluated against the testing set in order to assess their respective performances. We further attempt to tune the hyper parameters of the algorithms, in order to achieve better results. Random forest and extreme gradient boosting algorithms performed exceptionally well in our experiments, resulting in area under the curve values of 0.9928 and 0.9998 respectively. Our work demonstrates that malware traffic can be effectively classified using conventional machine learning algorithms and also shows the importance of dimensionality reduction in such classification problems. Keywords: Malware Detection, Extreme Gradient Boosting, Random Forest, Feature Selection.

scholarly journals Evaluating Variable Selection and Machine Learning Algorithms for Estimating Forest Heights by Combining Lidar and Hyperspectral Data

2020 ◽  
Vol 9 (9) ◽  
pp. 507
Author(s):  
Sanjiwana Arjasakusuma ◽  
Sandiaga Swahyu Kusuma ◽  
Stuart Phinn
Keyword(s):  
Machine Learning ◽  
Feature Selection ◽  
Learning Algorithms ◽  
Principal Component ◽  
Hyperspectral Data ◽  
Machine Learning Algorithms ◽  
Gradient Boosting ◽  
Support Vector ◽  
Forest Height ◽  
Extreme Gradient Boosting

Machine learning has been employed for various mapping and modeling tasks using input variables from different sources of remote sensing data. For feature selection involving high- spatial and spectral dimensionality data, various methods have been developed and incorporated into the machine learning framework to ensure an efficient and optimal computational process. This research aims to assess the accuracy of various feature selection and machine learning methods for estimating forest height using AISA (airborne imaging spectrometer for applications) hyperspectral bands (479 bands) and airborne light detection and ranging (lidar) height metrics (36 metrics), alone and combined. Feature selection and dimensionality reduction using Boruta (BO), principal component analysis (PCA), simulated annealing (SA), and genetic algorithm (GA) in combination with machine learning algorithms such as multivariate adaptive regression spline (MARS), extra trees (ET), support vector regression (SVR) with radial basis function, and extreme gradient boosting (XGB) with trees (XGbtree and XGBdart) and linear (XGBlin) classifiers were evaluated. The results demonstrated that the combinations of BO-XGBdart and BO-SVR delivered the best model performance for estimating tropical forest height by combining lidar and hyperspectral data, with R2 = 0.53 and RMSE = 1.7 m (18.4% of nRMSE and 0.046 m of bias) for BO-XGBdart and R2 = 0.51 and RMSE = 1.8 m (15.8% of nRMSE and −0.244 m of bias) for BO-SVR. Our study also demonstrated the effectiveness of BO for variables selection; it could reduce 95% of the data to select the 29 most important variables from the initial 516 variables from lidar metrics and hyperspectral data.

scholarly journals Machine Learning-Enabled 30-Day Readmission Model for Stroke Patients

2021 ◽  
Vol 12 ◽  
Author(s):  
Negar Darabi ◽  
Niyousha Hosseinichimeh ◽  
Anthony Noto ◽  
Ramin Zand ◽  
Vida Abedi
Keyword(s):  
Machine Learning ◽  
Feature Selection ◽  
Ischemic Stroke ◽  
Machine Learning Algorithms ◽  
Gradient Boosting ◽  
Support Vector ◽  
Percutaneous Gastrostomy ◽  
Targeted Interventions ◽  
Clinical Variables ◽  
Extreme Gradient Boosting

Background and Purpose: Hospital readmissions impose a substantial burden on the healthcare system. Reducing readmissions after stroke could lead to improved quality of care especially since stroke is associated with a high rate of readmission. The goal of this study is to enhance our understanding of the predictors of 30-day readmission after ischemic stroke and develop models to identify high-risk individuals for targeted interventions.Methods: We used patient-level data from electronic health records (EHR), five machine learning algorithms (random forest, gradient boosting machine, extreme gradient boosting–XGBoost, support vector machine, and logistic regression-LR), data-driven feature selection strategy, and adaptive sampling to develop 15 models of 30-day readmission after ischemic stroke. We further identified important clinical variables.Results: We included 3,184 patients with ischemic stroke (mean age: 71 ± 13.90 years, men: 51.06%). Among the 61 clinical variables included in the model, the National Institutes of Health Stroke Scale score above 24, insert indwelling urinary catheter, hypercoagulable state, and percutaneous gastrostomy had the highest importance score. The Model's AUC (area under the curve) for predicting 30-day readmission was 0.74 (95%CI: 0.64–0.78) with PPV of 0.43 when the XGBoost algorithm was used with ROSE-sampling. The balance between specificity and sensitivity improved through the sampling strategy. The best sensitivity was achieved with LR when optimized with feature selection and ROSE-sampling (AUC: 0.64, sensitivity: 0.53, specificity: 0.69).Conclusions: Machine learning-based models can be designed to predict 30-day readmission after stroke using structured data from EHR. Among the algorithms analyzed, XGBoost with ROSE-sampling had the best performance in terms of AUC while LR with ROSE-sampling and feature selection had the best sensitivity. Clinical variables highly associated with 30-day readmission could be targeted for personalized interventions. Depending on healthcare systems' resources and criteria, models with optimized performance metrics can be implemented to improve outcomes.

Machine Learning Approach for Predicting Lane-Change Maneuvers using the SHRP2 Naturalistic Driving Study Data

2021 ◽  
pp. 036119812110035
Author(s):  
Anik Das ◽  
Mohamed M. Ahmed
Keyword(s):  
Machine Learning ◽  
Prediction Accuracy ◽  
Machine Learning Algorithms ◽  
Support Vector ◽  
Lane Change ◽  
Adaptive Boosting ◽  
Extreme Gradient Boosting ◽  
Naturalistic Driving Study ◽  
Naturalistic Driving ◽  
Change Prediction

Accurate lane-change prediction information in real time is essential to safely operate Autonomous Vehicles (AVs) on the roadways, especially at the early stage of AVs deployment, where there will be an interaction between AVs and human-driven vehicles. This study proposed reliable lane-change prediction models considering features from vehicle kinematics, machine vision, driver, and roadway geometric characteristics using the trajectory-level SHRP2 Naturalistic Driving Study and Roadway Information Database. Several machine learning algorithms were trained, validated, tested, and comparatively analyzed including, Classification And Regression Trees (CART), Random Forest (RF), eXtreme Gradient Boosting (XGBoost), Adaptive Boosting (AdaBoost), Support Vector Machine (SVM), K Nearest Neighbor (KNN), and Naïve Bayes (NB) based on six different sets of features. In each feature set, relevant features were extracted through a wrapper-based algorithm named Boruta. The results showed that the XGBoost model outperformed all other models in relation to its highest overall prediction accuracy (97%) and F1-score (95.5%) considering all features. However, the highest overall prediction accuracy of 97.3% and F1-score of 95.9% were observed in the XGBoost model based on vehicle kinematics features. Moreover, it was found that XGBoost was the only model that achieved a reliable and balanced prediction performance across all six feature sets. Furthermore, a simplified XGBoost model was developed for each feature set considering the practical implementation of the model. The proposed prediction model could help in trajectory planning for AVs and could be used to develop more reliable advanced driver assistance systems (ADAS) in a cooperative connected and automated vehicle environment.

scholarly journals Recognition Technology of Athlete’s Limb Movement Combined Based on the Integrated Learning Algorithm

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Fei Tan ◽  
Xiaoqing Xie
Keyword(s):  
Machine Learning ◽  
Feature Selection ◽  
Learning Algorithm ◽  
Human Motion ◽  
Machine Learning Algorithms ◽  
Support Vector ◽  
Recording Device ◽  
Table Tennis ◽  
Movement Recognition ◽  
Random Forest Tree

Human motion recognition based on inertial sensor is a new research direction in the field of pattern recognition. It carries out preprocessing, feature selection, and feature selection by placing inertial sensors on the surface of the human body. Finally, it mainly classifies and recognizes the extracted features of human action. There are many kinds of swing movements in table tennis. Accurately identifying these movement modes is of great significance for swing movement analysis. With the development of artificial intelligence technology, human movement recognition has made many breakthroughs in recent years, from machine learning to deep learning, from wearable sensors to visual sensors. However, there is not much work on movement recognition for table tennis, and the methods are still mainly integrated into the traditional field of machine learning. Therefore, this paper uses an acceleration sensor as a motion recording device for a table tennis disc and explores the three-axis acceleration data of four common swing motions. Traditional machine learning algorithms (decision tree, random forest tree, and support vector) are used to classify the swing motion, and a classification algorithm based on the idea of integration is designed. Experimental results show that the ensemble learning algorithm developed in this paper is better than the traditional machine learning algorithm, and the average recognition accuracy is 91%.

Abstract 15895: Machine Learning Algorithms to Predict Major Adverse Cardiovascular Events in Patients Undergoing Orthotopic Liver Transplantation: A Retrospective Cohort Study

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
vardhmaan jain ◽  
Vikram Sharma ◽  
Agam Bansal ◽  
Cerise Kleb ◽  
Chirag Sheth ◽  
...  
Keyword(s):  
Machine Learning ◽  
Random Forest ◽  
Cardiovascular Events ◽  
Learning Algorithms ◽  
Machine Learning Algorithms ◽  
Major Adverse Cardiovascular Events ◽  
Support Vector ◽  
Post Transplant ◽  
Extreme Gradient Boosting ◽  
All Cause Mortality

Background: Post-transplant major adverse cardiovascular events (MACE) are amongst the leading cause of death amongst orthotopic liver transplant(OLT) recipients. Despite years of guideline directed therapy, there are limited data on predictors of post-OLT MACE. We assessed if machine learning algorithms (MLA) can predict MACE and all-cause mortality in patients undergoing OLT. Methods: We tested three MLA: support vector machine, extreme gradient boosting(XG-Boost) and random forest with traditional logistic regression for prediction of MACE and all-cause mortality on a cohort of consecutive patients undergoing OLT at our center between 2008-2019. The cohort was randomly split into a training (80%) and testing (20%) cohort. Model performance was assessed using c-statistic or AUC. Results: We included 1,459 consecutive patients with mean ± SD age 54.2 ± 13.8 years, 32% female who underwent OLT. There were 199 (13.6%) MACE and 289 (20%) deaths at a mean follow up of 4.56 ± 3.3 years. The random forest MLA was the best performing model for predicting MACE [AUC:0.78, 95% CI: 0.70-0.85] as well as mortality [AUC:0.69, 95% CI: 0.61-0.76], with all models performing better when predicting MACE vs mortality. See Table and Figure. Conclusion: Random forest machine learning algorithms were more predictive and discriminative than traditional regression models for predicting major adverse cardiovascular events and all-cause mortality in patients undergoing OLT. Validation and subsequent incorporation of MLA in clinical decision making for OLT candidacy could help risk stratify patients for post-transplant adverse cardiovascular events.

scholarly journals Diagnostic Performance of 2D and 3D T2WI-Based Radiomics Features With Machine Learning Algorithms to Distinguish Solid Solitary Pulmonary Lesion

2021 ◽  
Vol 11 ◽  
Author(s):  
Qi Wan ◽  
Jiaxuan Zhou ◽  
Xiaoying Xia ◽  
Jianfeng Hu ◽  
Peng Wang ◽  
...  
Keyword(s):  
Machine Learning ◽  
Feature Selection ◽  
Diagnostic Performance ◽  
Feature Selection Method ◽  
Machine Learning Algorithms ◽  
Support Vector ◽  
Learning Approaches ◽  
Selection Methods ◽  
Linear Discriminant ◽  
2D And 3D

ObjectiveTo evaluate the performance of 2D and 3D radiomics features with different machine learning approaches to classify SPLs based on magnetic resonance(MR) T2 weighted imaging (T2WI).Material and MethodsA total of 132 patients with pathologically confirmed SPLs were examined and randomly divided into training (n = 92) and test datasets (n = 40). A total of 1692 3D and 1231 2D radiomics features per patient were extracted. Both radiomics features and clinical data were evaluated. A total of 1260 classification models, comprising 3 normalization methods, 2 dimension reduction algorithms, 3 feature selection methods, and 10 classifiers with 7 different feature numbers (confined to 3–9), were compared. The ten-fold cross-validation on the training dataset was applied to choose the candidate final model. The area under the receiver operating characteristic curve (AUC), precision-recall plot, and Matthews Correlation Coefficient were used to evaluate the performance of machine learning approaches.ResultsThe 3D features were significantly superior to 2D features, showing much more machine learning combinations with AUC greater than 0.7 in both validation and test groups (129 vs. 11). The feature selection method Analysis of Variance(ANOVA), Recursive Feature Elimination(RFE) and the classifier Logistic Regression(LR), Linear Discriminant Analysis(LDA), Support Vector Machine(SVM), Gaussian Process(GP) had relatively better performance. The best performance of 3D radiomics features in the test dataset (AUC = 0.824, AUC-PR = 0.927, MCC = 0.514) was higher than that of 2D features (AUC = 0.740, AUC-PR = 0.846, MCC = 0.404). The joint 3D and 2D features (AUC=0.813, AUC-PR = 0.926, MCC = 0.563) showed similar results as 3D features. Incorporating clinical features with 3D and 2D radiomics features slightly improved the AUC to 0.836 (AUC-PR = 0.918, MCC = 0.620) and 0.780 (AUC-PR = 0.900, MCC = 0.574), respectively.ConclusionsAfter algorithm optimization, 2D feature-based radiomics models yield favorable results in differentiating malignant and benign SPLs, but 3D features are still preferred because of the availability of more machine learning algorithmic combinations with better performance. Feature selection methods ANOVA and RFE, and classifier LR, LDA, SVM and GP are more likely to demonstrate better diagnostic performance for 3D features in the current study.

scholarly journals A Hybrid Feature Selection Method for Improve the Accuracy of Medical Classification Process

2021 ◽  
Vol 11 (1) ◽  
pp. 50-55
Author(s):  
Maria Mohammad Yousef ◽  
Keyword(s):  
Machine Learning ◽  
Feature Selection ◽  
Dimensionality Reduction ◽  
Classification Accuracy ◽  
Fitness Function ◽  
Machine Learning Algorithms ◽  
Feature Subset Selection ◽  
High Dimensionality ◽  
Support Vector ◽  
Feature Subset

Generally, medical dataset classification has become one of the biggest problems in data mining research. Every database has a given number of features but it is observed that some of these features can be redundant and can be harmful as well as disrupt the process of classification and this problem is known as a high dimensionality problem. Dimensionality reduction in data preprocessing is critical for increasing the performance of machine learning algorithms. Besides the contribution of feature subset selection in dimensionality reduction gives a significant improvement in classification accuracy. In this paper, we proposed a new hybrid feature selection approach based on (GA assisted by KNN) to deal with issues of high dimensionality in biomedical data classification. The proposed method first applies the combination between GA and KNN for feature selection to find the optimal subset of features where the classification accuracy of the k-Nearest Neighbor (kNN) method is used as the fitness function for GA. After selecting the best-suggested subset of features, Support Vector Machine (SVM) are used as the classifiers. The proposed method experiments on five medical datasets of the UCI Machine Learning Repository. It is noted that the suggested technique performs admirably on these databases, achieving higher classification accuracy while using fewer features.

scholarly journals Application of machine learning algorithms for flood susceptibility assessment and risk management

2021 ◽  
Author(s):  
R. Madhuri ◽  
S. Sistla ◽  
K. Srinivasa Raju
Keyword(s):  
Climate Change ◽  
Machine Learning ◽  
Influencing Factors ◽  
Machine Learning Algorithms ◽  
Gradient Boosting ◽  
Support Vector ◽  
Climate Change Scenarios ◽  
Adaptive Boosting ◽  
Extreme Gradient Boosting ◽  
Normalised Difference Vegetation Index

Abstract Assessing floods and their likely impact in climate change scenarios will enable the facilitation of sustainable management strategies. In this study, five machine learning (ML) algorithms, namely (i) Logistic Regression, (ii) Support Vector Machine, (iii) K-nearest neighbor, (iv) Adaptive Boosting (AdaBoost) and (v) Extreme Gradient Boosting (XGBoost), were tested for Greater Hyderabad Municipal Corporation (GHMC), India, to evaluate their clustering abilities to classify locations (flooded or non-flooded) for climate change scenarios. A geo-spatial database, with eight flood influencing factors, namely, rainfall, elevation, slope, distance from nearest stream, evapotranspiration, land surface temperature, normalised difference vegetation index and curve number, was developed for 2000, 2006 and 2016. XGBoost performed the best, with the highest mean area under curve score of 0.83. Hence, XGBoost was adopted to simulate the future flood locations corresponding to probable highest rainfall events under four Representative Concentration Pathways (RCPs), namely, 2.6, 4.5, 6.0 and 8.5 along with other flood influencing factors for 2040, 2056, 2050 and 2064, respectively. The resulting ranges of flood risk probabilities are predicted as 39–77%, 16–39%, 42–63% and 39–77% for the respective years.

scholarly journals Systematic Evaluation of Machine Learning Algorithms for Neuroanatomically-Based Age Prediction in Youth

2021 ◽  
Author(s):  
Mandana Modabbernia ◽  
Heather C Whalley ◽  
David Glahn ◽  
Paul M. Thompson ◽  
Rene S. Kahn ◽  
...  
Keyword(s):  
Machine Learning ◽  
Computational Efficiency ◽  
Learning Algorithms ◽  
Machine Learning Algorithms ◽  
Sensitivity Analyses ◽  
Gradient Boosting ◽  
Support Vector ◽  
Age Related ◽  
Extreme Gradient Boosting ◽  
Brain Age

Application of machine learning algorithms to structural magnetic resonance imaging (sMRI) data has yielded behaviorally meaningful estimates of the biological age of the brain (brain-age). The choice of the machine learning approach in estimating brain-age in children and adolescents is important because age-related brain changes in these age-groups are dynamic. However, the comparative performance of the multiple machine learning algorithms available has not been systematically appraised. To address this gap, the present study evaluated the accuracy (Mean Absolute Error; MAE) and computational efficiency of 21 machine learning algorithms using sMRI data from 2,105 typically developing individuals aged 5 to 22 years from five cohorts. The trained models were then tested in an independent holdout datasets, comprising 4,078 pre-adolescents (aged 9-10 years). The algorithms encompassed parametric and nonparametric, Bayesian, linear and nonlinear, tree-based, and kernel-based models. Sensitivity analyses were performed for parcellation scheme, number of neuroimaging input features, number of cross-validation folds, and sample size. The best performing algorithms were Extreme Gradient Boosting (MAE of 1.25 years for females and 1.57 years for males), Random Forest Regression (MAE of 1.23 years for females and 1.65 years for males) and Support Vector Regression with Radial Basis Function Kernel (MAE of 1.47 years for females and 1.72 years for males) which had acceptable and comparable computational efficiency. Findings of the present study could be used as a guide for optimizing methodology when quantifying age-related changes during development.

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