Laryngeal Verrucous Carcinoma

Pariket M. Dubal; Peter F. Svider; David Kam; Rahul Dutta; Soly Baredes; Jean Anderson Eloy

doi:10.1177/0194599815591981

Multidisciplinary Approach of a Very Rare Infected Verrucous Carcinoma of the Scrotum

Revista de Chimie ◽

10.37358/rc.19.4.7153 ◽

2019 ◽

Vol 70 (4) ◽

pp. 1476-1478

Author(s):

Laura Raducu ◽

Adelaida Avino ◽

Cristina-Nicoleta Cozma ◽

Sorin Nedelea ◽

Andra-Elena Balcangiu-Stroescu ◽

...

Keyword(s):

Adjuvant Therapy ◽

Rare Disease ◽

Chronic Inflammation ◽

Male Patient ◽

Multidisciplinary Approach ◽

Verrucous Carcinoma ◽

Surgical Excision ◽

Diagnosis And Treatment ◽

Wide Surgical Excision ◽

The Right

Verrucous carcinoma of the scrotum is an extremely rare disease and most cases are thought to result from poor hygiene and chronic inflammation. Currently, it has not been well characterized, the etiology, diagnosis and treatment remaining poorly understood. We present the case of a 50-year-old male patient diagnosed with verrucous carcinoma of the right hemiscrotum. Wide surgical excision was performed. Favorable outcomes can be achieved by surgery, even without any adjuvant therapy, but patients should be carefully followed up.

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Oral Cancer: Raising Awareness of the Importance of Suspicion in Early Detection

Primary Dental Journal ◽

10.1177/2050168420980959 ◽

2021 ◽

Vol 10 (1) ◽

pp. 10-12

Author(s):

Farooq Ahmed ◽

Honieh Bolooki ◽

Senathrajah Ariyaratnam ◽

Michael N. Pemberton

Keyword(s):

Squamous Cell Carcinoma ◽

Oral Cancer ◽

Early Detection ◽

Cell Carcinoma ◽

Squamous Cell ◽

Verrucous Carcinoma ◽

Mucosal Lesion ◽

Morbidity And Mortality ◽

Raising Awareness ◽

Suspicious Lesions

Oral cancer is a significant cause of morbidity and mortality worldwide. In this article we present two cases of potentially innocuous looking lesions, initially thought to be traumatic in origin, but later diagnosed as cancer. The first patient presented with a persistent laceration thought to be caused by an accidental shaving injury, which was subsequently diagnosed as squamous cell carcinoma. The second patient presented with a hyperplastic mucosal lesion, suspected as forming due to denture-clasp irritation, which was subsequently diagnosed as proliferative verrucous carcinoma. The importance of early detection and palpation of suspicious lesions is emphasised in this article.

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Pseudoepitheliomatous keratotic and micaceous balanitis: low-risk human papilloma virus detection in two further cases

International Journal of STD & AIDS ◽

10.1177/0956462420961947 ◽

2020 ◽

pp. 095646242096194

Author(s):

Marialuisa Corbeddu ◽

Luca Pilloni ◽

Roberta Satta ◽

Laura Atzori ◽

Franco Rongioletti

Keyword(s):

Human Papillomavirus ◽

Verrucous Carcinoma ◽

Virus Detection ◽

Low Risk ◽

Hpv Testing ◽

Papilloma Virus ◽

Hpv Dna ◽

Proliferative Markers ◽

Male Patients ◽

Papillomavirus Dna

We report two cases of histologically documented pseudoepitheliomatous keratotic and micaceous balanitis in middle-aged male patients, which showed positivity for low-risk serotype human papillomavirus DNA. To our knowledge, only one other case has been documented. Further immunohistochemical proliferative markers were performed and compared to literature findings in penile epithelial proliferations. Evolution to invasive verrucous carcinoma has been associated with absence of HPV DNA. Thus, if confirmed by further studies, HPV testing should be included in pseudoepitheliomatous keratotic and micaceous balanitis assessment to address prognosis, and management.

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Research on miRNA-195 and target gene CDK6 in oral verrucous carcinoma

Cancer Gene Therapy ◽

10.1038/cgt.2017.18 ◽

2017 ◽

Vol 24 (7) ◽

pp. 282-288 ◽

Cited By ~ 7

Author(s):

Z Deng ◽

Y Wang ◽

X Fang ◽

F Yan ◽

H Pan ◽

...

Keyword(s):

Target Gene ◽

Verrucous Carcinoma

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Intra-Abdominal Localisation of a Buschke-Lowenstein Tumour: Case Presentation and Review of the Literature

Case Reports in Transplantation ◽

10.1155/2013/187682 ◽

2013 ◽

Vol 2013 ◽

pp. 1-6 ◽

Cited By ~ 2

Author(s):

N. E. Wester ◽

E. M. Hutten ◽

C. Krikke ◽

Robert A. Pol

Keyword(s):

Interferon Therapy ◽

Verrucous Carcinoma ◽

Treatment Options ◽

Condyloma Acuminata ◽

Review Of The Literature ◽

Case Presentation ◽

Advantages And Disadvantages ◽

Literature Overview ◽

Mucosal Surfaces ◽

Tumour Reduction

Giant condyloma acuminatum or Buschke-Lowenstein tumour is a very rare disease which usually is located in the genital, anorectal, and perianal regions. It is regarded as a type of verrucous carcinoma occurring on anogenital mucosal surfaces where it is locally invasive but displays a benign cytology. We describe a case of a 24-year-old woman with persisting condyloma acuminata progressing to a large intra-abdominal Buschke-Lowenstein tumour. To our knowledge such an advanced stage has only been reported once before. The severity and extent of the tumour both determine the treatment and patient outcome. Treatment was impeded by cachexia, an immunosuppressive state after kidney transplantation and difficulties in establishing a reliable diagnose. Interferon treatment was started which initially led to tumour reduction but was complicated by an interferon-induced pancreatitis, pneumonia, and fasciitis necroticans resulting in death. We present a literature overview on the treatment options for a Buschke-Lowenstein tumour, with emphasis on interferon therapy, with all the advantages and disadvantages.

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Effective eradication of oral verrucous carcinoma with continuous intraarterial infusion chemotherapy

Head & Neck ◽

10.1002/hed.20751 ◽

2008 ◽

Vol 30 (5) ◽

pp. 611-617 ◽

Cited By ~ 26

Author(s):

Chih-Fung Wu ◽

Chung-Ming Chen ◽

Yee-Shyong Shen ◽

I-Yueh Huang ◽

Chung-Ho Chen ◽

...

Keyword(s):

Verrucous Carcinoma ◽

Intraarterial Infusion ◽

Infusion Chemotherapy

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Verrucous carcinoma of the mouth

Journal of Oral and Maxillofacial Surgery ◽

10.1016/s0278-2391(96)90774-0 ◽

1996 ◽

Vol 54 (3) ◽

pp. 375

Author(s):

G.H Sperber

Keyword(s):

Verrucous Carcinoma

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Aggressive verrucous carcinoma of the paranasal sinuses invading the orbit: case report and literature review

The Journal of Laryngology & Otology ◽

10.1017/s0022215109990648 ◽

2009 ◽

Vol 123 (11) ◽

Cited By ~ 6

Author(s):

J Yiotakis ◽

T Vamvakidis ◽

E Iakovou ◽

L Manolopoulos

Keyword(s):

Case Report ◽

Paranasal Sinuses ◽

Verrucous Carcinoma ◽

Transnasal Approach ◽

Early Management ◽

Combined Radiochemotherapy ◽

Endoscopic Transnasal Approach ◽

Well Differentiated ◽

Orbital Invasion ◽

Histological Result

AbstractIntroduction:Verrucous carcinoma is a variant of well differentiated squamous cell carcinoma characterised by an exophytic, warty growth which is slowly but locally invasive and which can cause extensive local destruction if left untreated.Case report:We report the first known case of veruccous carcinoma of the paranasal sinuses with rapid orbital invasion. A 58-year-old man presented with right-sided nasal obstruction, a huge right intranasal lesion, intractable dacryocystitis and cutaneous involvement of the nasolacrimal sac region. The tumour was partially removed using an endoscopic transnasal approach. Post-operatively, and while waiting for the histological result, the patient developed signs of rapid invasion of the orbit, with uniocular visual acuity deficit. He underwent combined radiochemotherapy, with a moderate response.Conclusion:Knowledge of the potentially aggressive nature of verrucous carcinoma may be helpful in early management of intraorbital invasion and salvaging of the eye.

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Verrucous carcinoma of the esophagus – a case report and literature review

Zeitschrift für Gastroenterologie ◽

10.1055/a-1231-5820 ◽

2020 ◽

Vol 58 (10) ◽

pp. 971-974

Author(s):

Thomas Frieling ◽

Christian Kreysel ◽

Michael Blank ◽

Dorothee Müller ◽

P. Euler ◽

...

Keyword(s):

Case Report ◽

Literature Review ◽

Verrucous Carcinoma ◽

Tumor Stage ◽

Esophageal Resection ◽

Middle Part ◽

Herpes Simplex Virus 1 ◽

Carcinoma Of The Esophagus ◽

Tissue Specimens ◽

Simplex Virus

Abstract Background Verrucous carcinoma of the esophagus is a rare disease leading to dysphagia, chest pain, and weight loss. The diagnosis is difficult because even repeated biopsies are often without tumor evidence. We present a patient with verrucous carcinoma of the esophagus and a literature review. Case report A 64-year-old patient with dysphagia and sore throat received esophagogastroduodenoscopy illustrating segmental circumferential verrucous inflammation and Candida esophagitis in the middle part of the esophagus. Repeated mucosal biopsies revealed reactive hyperkeratosis of the squamous epithelium with minimal atypia but without ulcera, eosinophilic esophagitis, or suspicion of cancer. Mucosal infection with adenovirus, herpes simplex virus 1, human papilloma virus types, and cytomegaly virus was ruled out. Veruccous carcinoma was detected finally by endoscopic mucosal resection. The patient was successfully treated by esophageal resection. Tumor stage was G1, pT1b, pN0, L0, V0, Pn0, R0. Conclusion The results suggest that macroscopic suspicion of verrucous esophageal carcinoma should lead to resections of larger tissue specimens by EMR to confirm the diagnosis.

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