scholarly journals Major Vascular Injury during Lumbar Laminectomy

1996 ◽  
Vol 89 (2) ◽  
pp. 108P-109P ◽  
Author(s):  
E Ezra ◽  
J L Richenberg ◽  
W A B Smellie
Keyword(s):  
Early Diagnosis ◽  
Vascular Injury ◽  
Surgical Procedures ◽  
Rare Complication ◽  
Morbidity And Mortality ◽  
High Morbidity ◽  
Early Stages ◽  
Major Vascular Injury

Major vascular injury during lumbar laminectomy is an extremely rare complication of one of the commonest surgical procedures performed in orthopaedic and neurosurgical units. Its occurrence may be associated with high morbidity and mortality, particularly if it is not diagnosed in the early stages. Early diagnosis and repair is associated with an improved prognosis in the long term. We illustrate these points with a description of two cases, and discuss the anatomical factors predisposing to these injuries and the importance of angiography in the management and early diagnosis of suspected cases.

scholarly journals Pneumocephalus Following Self-Inflicted Penetrating Brain Injury

2017 ◽  
Vol 2017 ◽  
pp. 1-3
Author(s):  
Che-Fang Ho ◽  
Yuan-Yun Tam ◽  
Chia-Chen Wu
Keyword(s):  
Rare Complication ◽  
Bed Rest ◽  
Morbidity And Mortality ◽  
High Morbidity ◽  
Adequate Treatment ◽  
Cerebrospinal Fluid Rhinorrhea ◽  
Intravenous Antibiotics ◽  
Computed Tomography Scans ◽  
Intravenous Hydration ◽  
Prompt Diagnosis

Objective. Pneumocephalus is a rare complication that often occurs after traumatic skull base injury, leading to morbidity and mortality. Material and Method. We present the case of a 42-year-old healthy man who injured himself when he stuck a metal stick into his left nasal cavity to relieve prolonged nasal obstruction. Immediate cerebrospinal fluid rhinorrhea and subsequent meningitis and pneumocephalus occurred later. He was presented at our hospital with fever and meningeal signs. Result. Computed tomography scans revealed left rhinosinusitis and air collection in the subarachnoid space. The patient received the conservative treatment of bed rest, intravenous hydration, head elevation, and broad-spectrum intravenous antibiotics. Pneumocephalus and meningitis resolved without any surgery, and he experienced no other sequela or complication. Conclusion. Pneumocephalus is a rare incidence and can lead to high morbidity and mortality. Prompt diagnosis and adequate treatment of pneumocephalus and meningitis proved beneficial for our patient who recovered without any complication or surgery.

scholarly journals The Diagnostic and Therapeutic Value of Multimarker Analysis in Heart Failure. An Approach to Biomarker-Targeted Therapy

2020 ◽  
Vol 7 ◽  
Author(s):  
Albert Topf ◽  
Moritz Mirna ◽  
Bernhard Ohnewein ◽  
Peter Jirak ◽  
Kristen Kopp ◽  
...  
Keyword(s):  
Heart Failure ◽  
Morbidity And Mortality ◽  
Therapeutic Interventions ◽  
Stress Axis ◽  
High Morbidity ◽  
Matrix Remodeling ◽  
Therapeutic Approaches ◽  
Therapeutic Setting ◽  
Therapeutic Value

Background: Heart failure is a pathophysiological state, which is still associated with high morbidity and mortality despite established therapies. Diverse well-known biomarkers fail to assess the variety of individual pathophysiology in the context of heart failure.Methods: An analysis of prospective, multimarker-specific therapeutic approaches to heart failure based on studies in current literature was performed. A total of 159 screened publications in the field of biomarkers in heart failure were hand-selected and found to be eligible for this study by a team of experts.Results: Established biomarkers of the inflammatory axis, matrix remodeling, fibrosis and oxidative stress axis, as well as potential therapeutic interventions were investigated. Interaction with end organs, such as cardio-hepatic, cardio-renal and cardio-gastrointestinal interactions show the complexity of the syndrome and could be of further therapeutic value. MicroRNAs are involved in a wide variety of physiologic and pathophysiologic processes in heart failure and could be useful in diagnostic as well as therapeutic setting.Conclusion: Based on our analysis by a biomarker-driven approach in heart failure therapy, patients could be treated more specifically in long term with a consideration of different aspects of heart failure. New studies evaluating a multimarker – based therapeutic approach could lead in a decrease in the morbidity and mortality of heart failure patients.

scholarly journals Cardiovascular and Metabolic Consequences of Liver Transplantation: A Review

Medicina ◽  
2019 ◽  
Vol 55 (8) ◽  
pp. 489
Author(s):  
Plotogea ◽  
Ilie ◽  
Sandru ◽  
Chiotoroiu ◽  
Bratu ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Liver Transplantation ◽  
De Novo ◽  
Current Knowledge ◽  
Morbidity And Mortality ◽  
High Morbidity ◽  
Term Survival ◽  
The Metabolic Syndrome ◽  
Acute Liver Disease

Liver transplantation (LT) is considered the curative treatment option for selected patients who suffer from end-stage or acute liver disease or hepatic malignancy (primary). After LT, patients should be carefully monitored for complications that may appear, partially due to immunosuppressive therapy, but not entirely. Cardiovascular diseases are frequently encountered in patients with LT, being responsible for high morbidity and mortality. Patients with underlying cardiovascular and metabolic pathologies are prone to complications after the transplant, but these complications can also appear de novo, mostly associated with immunosuppressants. Metabolic syndrome, defined by obesity, hypertension, dyslipidemia, and hyperglycemia, is diagnosed among LT recipients and is aggravated after LT, influencing the long-term survival. In this review, our purpose was to summarize the current knowledge regarding cardiovascular (CV) diseases and the metabolic syndrome associated with LT and to assess their impact on short and long-term morbidity and mortality.

Subcapsular hepatic haematoma after endoscopic retrograde cholangiopancreatography. A rare complication with high morbidity and mortality

2019 ◽  
Vol 42 (1) ◽  
pp. 23-27
Author(s):  
Jon de la Maza Ortiz ◽  
Seila García Mulas ◽  
Juan Carlos Ávila Alegría ◽  
Javier García Lledó ◽  
Leticia Pérez Carazo ◽  
...  
Keyword(s):  
Endoscopic Retrograde Cholangiopancreatography ◽  
Rare Complication ◽  
Morbidity And Mortality ◽  
High Morbidity ◽  
Endoscopic Retrograde ◽  
Hepatic Haematoma

Morbidity and Mortality of C2 Fractures in the Elderly

Neurosurgery ◽  
2011 ◽  
Vol 70 (5) ◽  
pp. 1055-1059 ◽  
Author(s):  
Yi-Ren Chen ◽  
Maxwell Boakye ◽  
Robert T. Arrigo ◽  
Paul S. A. Kalanithi ◽  
Ivan Cheng ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Hospital Stay ◽  
Treatment Modality ◽  
The Elderly ◽  
Morbidity And Mortality ◽  
High Morbidity ◽  
Complication Rates ◽  
Term Survival ◽  
Cord Injury

Abstract BACKGROUND: Closed C2 fractures commonly occur after falls or other trauma in the elderly and are associated with significant morbidity and mortality. Controversy exists as to best treatment practices for these patients. OBJECTIVE: To compare outcomes for elderly patients with closed C2 fractures by treatment modality. METHODS: We retrospectively reviewed 28 surgically and 28 nonsurgically treated cases of closed C2 fractures without spinal cord injury in patients aged 65 years of age or older treated at Stanford Hospital between January 2000 and July 2010. Comorbidities, fracture characteristics, and treatment details were recorded; primary outcomes were 30-day mortality and complication rates; secondary outcomes were length of hospital stay and long-term survival. RESULTS: Surgically treated patients tended to have more severe fractures with larger displacement. Charlson comorbidity scores were similar in both groups. Thirty-day mortality was 3.6% in the surgical group and 7.1% in the nonsurgical group, and the 30-day complication rates were 17.9% and 25.0%, respectively; these differences were not statistically significant. Surgical patients had significantly longer lengths of hospital stay than nonsurgical patients (11.8 days vs 4.4 days). Long-term median survival was not significantly different between groups. CONCLUSION: The 30-day mortality and complication rates in surgically and nonsurgically treated patients were comparable. Elderly patients faced relatively high morbidity and mortality regardless of treatment modality; thus, age alone does not appear to be a contraindication to surgical fixation of C2 fractures.

scholarly journals Tetanus: A Rare Complication of Black Tar Heroin Use

2021 ◽  
Author(s):  
Elisa Pichlinski ◽  
Emily Hoff ◽  
Lindsey Claire Epperson ◽  
Elizabeth Morley ◽  
James Dazhe Cao ◽  
...  
Keyword(s):  
Harm Reduction ◽  
Rare Complication ◽  
High Income ◽  
Morbidity And Mortality ◽  
High Morbidity ◽  
Heroin Use ◽  
Tetanus Vaccination ◽  
Vaccination Campaigns

Abstract Tetanus is associated with high morbidity and mortality, though rarely encountered in high-income countries. We present a case of tetanus in an unvaccinated patient secondary to black tar heroin use that highlights the importance of consideration of tetanus in appropriate clinical contexts, harm reduction interventions and universal tetanus vaccination campaigns.

scholarly journals Multivalvular Endocarditis Involving 3 Valves in a Nonsurgical Candidate

2020 ◽  
Vol 8 ◽  
pp. 232470962093685
Author(s):  
Robin Boyer ◽  
Sundeep Grandhe ◽  
Theingi Win ◽  
Alan Ragland ◽  
Arash Heidari
Keyword(s):  
Surgical Treatment ◽  
Infective Endocarditis ◽  
Early Diagnosis ◽  
Morbidity And Mortality ◽  
High Morbidity ◽  
Healthy Male ◽  
Septic Emboli ◽  
Best Management ◽  
Nonsurgical Patients

Infective endocarditis is associated with high morbidity and mortality. Hence, early diagnosis and prompt intervention is crucial. Multivalvular endocarditis involving 3 or more valves is rarely reported with little information regarding best management or prognosis, particularly in nonsurgical patients. Conflicting guidelines regarding medical versus surgical treatment in multivalvular endocarditis exist with few studies describing the outcome of medically managed patients. We report the case of a previously healthy male presenting with infective endocarditis involving 3 valves further complicated by multiple septic emboli and deemed a nonsurgical candidate.

scholarly journals COVID-19 and Ontario’s Long-Term Care Homes

2020 ◽  
Author(s):  
Nathan M. Stall ◽  
Kevin A. Brown ◽  
Aaron Jones ◽  
Andrew P. Costa ◽  
Vanessa Allen ◽  
...  
Keyword(s):  
Working Conditions ◽  
Long Term Care ◽  
Morbidity And Mortality ◽  
High Morbidity ◽  
Temporary Housing ◽  
Term Care ◽  
High Burden ◽  
Second Homes ◽  
Temporary Staffing

Ontario long-term care (LTC) home residents have experienced disproportionately high morbidity and mortality, both from COVID-19 and from the conditions associated with the COVID-19 pandemic. There are several measures that could be effective in preventing COVID-19 outbreaks, hospitalizations, and deaths in Ontario’s LTC homes, if implemented. First, temporary staffing could be minimized by improving staff working conditions. Second, homes could be further decrowded by a continued disallowance of three- and four-resident rooms and additional temporary housing for the most crowded homes. Third, the risk of SARS-CoV-2 infection in staff could be minimized by approaches that reduce the risk of transmission in communities with a high burden of COVID-19.

scholarly journals COVID-19 and Ontario’s Long-Term Care Homes

2021 ◽  
Vol 1 (3) ◽  
Author(s):  
Nathan M. Stall
Keyword(s):  
Long Term Care ◽  
Morbidity And Mortality ◽  
Care Homes ◽  
High Morbidity ◽  
Term Care

Ontario long-term care (LTC) home residents have experienced disproportionately high morbidity and mortality, both from COVID-19 and from the conditions associated with the COVID-19 pandemic. As of July 10, 2021, a total of 3,975 LTC home residents have died of COVID-19, totaling 43.0% of all 9,245 COVID-19 deaths in Ontario.

Endovascular treatment of mycotic pseudoaneurysms

VASA ◽  
2010 ◽  
Vol 39 (3) ◽  
pp. 256-261 ◽  
Author(s):  
Vávrova ◽  
Jonszta ◽  
Czerný ◽  
Hrbac ◽  
Lipina ◽  
...  
Keyword(s):  
Coil Embolization ◽  
Pediatric Patients ◽  
Artery Occlusion ◽  
Morbidity And Mortality ◽  
Parent Artery ◽  
High Morbidity ◽  
Prolonged Administration ◽  
Parent Artery Occlusion ◽  
Lower Morbidity

The surgical correction of ruptured intracranial infectious pseudoaneurysms is associated with high morbidity and mortality. An endovascular therapeutic approach has been introduced recently. This treatment is, compared to surgical intervention, less invasive, faster, more effective and safer, thus making it a gentler option, particularly for pediatric patients. Lower morbidity and mortality have been achieved thanks to the combination of prolonged administration of antibiotics, coil embolization, and parent artery occlusion. Two pediatric cases of bleeding mycotic pseudoaneurysm treated successfully with fibered coil embolization and long-term antibiotics are dealt with in this manuscript.

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