The Impact of IV Electrolyte Replacement on the Fluid Balance of Critically Ill Surgical Patients

2019 ◽  
Vol 85 (10) ◽  
pp. 1171-1174 ◽  
Author(s):  
Andrew S. Wang ◽  
Navpreet K. Dhillon ◽  
Nikhil T. Linaval ◽  
Nicholas Rottler ◽  
Audrey R. Yang ◽  
...  

Avoiding excess fluid administration is necessary when managing critically ill surgical patients. The aim of this study was to delineate the current practices of IVelectrolyte (IVE) replacement in a surgical ICU and quantify their contribution to the fluid balance (FB) status. Patients admitted to the surgical ICU over a six-month period were reviewed. Patients undergoing dialysis and those with ICU stay <72 hours were excluded. A total of 248 patients were included. The median age was 60 years, and 57 per cent were male. Overall, 1131 patient ICU days were analyzed. The median daily FB was 672 mL. IVEs were administered in 62 per cent of ICU days. In days that IVEs were used, negative FB was significantly less likely to be achieved (62% vs 69%, P = 0.02). The most commonly administered IVE was calcium (32% of ICU days); however, the largest volume of IVE was administered in the form of phosphorus (median 225 mL). Diuretics were administered in 17 per cent of ICU days. Patients who received diuretics were significantly more likely to receive IVE (70% vs 61%, P = 0.02). Administration of IVE may contribute to the daily positive FB of surgical ICU patients. Implementation of practices that can ameliorate this effect is encouraged.

2021 ◽  
Vol 10 (21) ◽  
pp. 4873
Author(s):  
Chieh-Liang Wu ◽  
Kai-Chih Pai ◽  
Li-Ting Wong ◽  
Min-Shian Wang ◽  
Wen-Cheng Chao

Fluid balance is an essential issue in critical care; however, the impact of early fluid balance on the long-term mortality in critically ill surgical patients remains unknown. This study aimed to address the impact of day 1–3 and day 4–7 fluid balance on the long-term mortality in critically ill surgical patients. We enrolled patients who were admitted to surgical intensive care units (ICUs) during 2015–2019 at a tertiary hospital in central Taiwan and retrieved date-of-death from the Taiwanese nationwide death registration profile. We used a Log-rank test and a multivariable Cox proportional hazards regression model to determine the independent mortality impact of early fluid balance. A total of 6978 patients were included for analyses (mean age: 60.9 ± 15.9 years; 63.9% of them were men). In-hospital mortality, 90-day mortality, 1-year and overall mortality was 10.3%, 15.8%, 23.8% and 31.7%, respectively. In a multivariable Cox proportional hazard regression model adjusted for relevant covariates, we found that positive cumulative day 4–7 fluid balance was independently associated with long-term mortality (aHR 1.083, 95% CI 1.062–1.105), and a similar trend was found on day 1–3 fluid balance, although to a lesser extent (aHR 1.027, 95% CI 1.011–1.043). In conclusion, the fluid balance in the first week of ICU stay, particularly day 4–7 fluid balance, may affect the long-term outcome in critically ill surgical patients.


2014 ◽  
Vol 29 (6) ◽  
pp. 936-941 ◽  
Author(s):  
Galinos Barmparas ◽  
Douglas Liou ◽  
Debora Lee ◽  
Nicole Fierro ◽  
Matthew Bloom ◽  
...  

2022 ◽  
pp. 000313482110697
Author(s):  
Bethany R. Shoulders ◽  
Sarah Elsabagh ◽  
Douglas J. Tam ◽  
Amanda M. Frantz ◽  
Kaitlin M. Alexander ◽  
...  

Background Delirium occurs frequently in critically ill and injured patients and is associated with significant morbidity and mortality. Limited data exists on the risk factors for developing delirium in critically ill trauma patients and the effect of antipsychotic (AP) medications on delirium progression. Objective The objective of this study is to determine the incidence of delirium in critically ill trauma versus non-trauma surgical patients and determine if the presence of trauma was associated with intensive care unit (ICU) delirium. Secondary outcomes included identifying risk factors for delirium and determining the impact of AP medication use on delirium progression in critically ill trauma patients. Methods This retrospective review studies adult trauma/surgical ICU patients admitted between May 2017-July 2018 to a level I trauma and tertiary referral center. Regression modeling was used to determine the impact of AP use on delirium-free days. Results Delirium was more common in critically ill trauma patients versus non-trauma surgical ICU patients [54/157 (34.4%) vs 42/270 (15.6%), P < .001]. Of the 54 trauma patients with delirium, 28 (52%) received an AP medication for delirium treatment and in the multiple linear regression analysis, AP use was significantly associated with fewer delirium-free days ( P = .02). Discussion Higher admission sequential organ failure assessment scores and increased length of stay were significantly associated with delirium onset in critically ill trauma patients. Use of AP medications for delirium treatment in this population had a negative impact on delirium-free days.


2012 ◽  
Vol 27 (1) ◽  
pp. 73-82 ◽  
Author(s):  
Christian P. Schneider ◽  
Jan Fertmann ◽  
Johannes Miesen ◽  
Hilde Wolf ◽  
Claudia Flexeder ◽  
...  

CHEST Journal ◽  
2015 ◽  
Vol 148 (4) ◽  
pp. 496A
Author(s):  
Adel Bassily Marcus ◽  
Jun Makino ◽  
Raja Singh ◽  
Ehizode Udevbulu ◽  
John Oropello ◽  
...  

2013 ◽  
Vol 184 (2) ◽  
pp. 966-972.e4 ◽  
Author(s):  
Jahan Porhomayon ◽  
Nader D. Nader ◽  
Ali A. El-Solh ◽  
Mindee Hite ◽  
Jonathan Scott ◽  
...  

1994 ◽  
Vol 22 (6) ◽  
pp. 956-959 ◽  
Author(s):  
JUHA M. GröNROOS ◽  
KARI KUTTILA ◽  
TIMO J. NEVALAJNEN

Sign in / Sign up

Export Citation Format

Share Document