scholarly journals Isolation of mycobacterium-reactive CD1-restricted T cells from patients with human immunodeficiency virus infection.

1998 ◽  
Vol 101 (2) ◽  
pp. 383-389 ◽  
Author(s):  
J Gong ◽  
S Stenger ◽  
J A Zack ◽  
B E Jones ◽  
G C Bristol ◽  
...  
Immunology ◽  
2003 ◽  
Vol 108 (1) ◽  
pp. 3-9 ◽  
Author(s):  
Richardson Fleuridor ◽  
Brian Wilson ◽  
Runhua Hou ◽  
Alan Landay ◽  
Harold Kessler ◽  
...  

2001 ◽  
Vol 183 (4) ◽  
pp. 555-562 ◽  
Author(s):  
Timothy Schacker ◽  
Susan Little ◽  
Elizabeth Connick ◽  
Kristin Gebhard ◽  
Zhi‐Qiang Zhang ◽  
...  

2009 ◽  
Vol 83 (7) ◽  
pp. 3374-3378 ◽  
Author(s):  
Dimitrios N. Vatakis ◽  
Christopher C. Nixon ◽  
Gregory Bristol ◽  
Jerome A. Zack

ABSTRACT The activation state of CD4+ T cells plays a crucial role in the establishment of a productive human immunodeficiency virus infection. Here, we show that T cells stimulated for 1 day demonstrated delayed kinetics of viral reverse transcription and integration compared to cells stimulated for 2 days prior to infection. As a result, the efficiency of reverse transcription and integration inhibitors differs in these differentially stimulated cells. These studies increase our understanding of how T cells support viral replication and provide insight regarding the efficiency of antiretroviral therapy in lymphoid compartments.


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