The antifungal antibiotic, clotrimazole, inhibits chloride secretion by human intestinal T84 cells via blockade of distinct basolateral K+ conductances. Demonstration of efficacy in intact rabbit colon and in an in vivo mouse model of cholera.

P A Rufo; D Merlin; M Riegler; M H Ferguson-Maltzman; B L Dickinson; C Brugnara; S L Alper; W I Lencer

doi:10.1172/jci119866

The antifungal antibiotic, clotrimazole, inhibits chloride secretion by human intestinal T84 cells via blockade of distinct basolateral K+ conductances. Demonstration of efficacy in intact rabbit colon and in an in vivo mouse model of cholera.

Journal of Clinical Investigation ◽

10.1172/jci119866 ◽

1997 ◽

Vol 100 (12) ◽

pp. 3111-3120 ◽

Cited By ~ 92

Author(s):

P A Rufo ◽

D Merlin ◽

M Riegler ◽

M H Ferguson-Maltzman ◽

B L Dickinson ◽

...

Keyword(s):

Mouse Model ◽

Chloride Secretion ◽

T84 Cells ◽

Antifungal Antibiotic ◽

Rabbit Colon ◽

Intact Rabbit

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Review for "Humanized CD22 transgenic mouse model for in vivo analysis of anti‐CD22‐based immunotherapy"

10.1002/eji.202048636/v2/review1 ◽

2020 ◽

Author(s):

Matthew Macauley

Keyword(s):

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model

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Review for "Humanized CD22 transgenic mouse model for in vivo analysis of anti‐CD22‐based immunotherapy"

10.1002/eji.202048636/v1/review1 ◽

2020 ◽

Keyword(s):

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model

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A Cre-loxP based mouse model for conditional somatic gene expression and knock-down in vivo using avian retroviral vectors

Zeitschrift für Gastroenterologie ◽

10.1055/s-0028-1089500 ◽

2008 ◽

Vol 46 (09) ◽

Author(s):

B Seidler ◽

A Schmidt ◽

U Mayr ◽

H Nakkhei ◽

RM Schmid ◽

...

Keyword(s):

Gene Expression ◽

Mouse Model ◽

Retroviral Vectors ◽

Knock Down ◽

Somatic Gene

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In Vivo Monitoring of Human Platelets in a Humanised Rag2−/− γ-chain−/− Mouse Model

The Thoracic and Cardiovascular Surgeon ◽

10.1055/s-0035-1544477 ◽

2015 ◽

Vol 63 (S 01) ◽

Author(s):

C. Heim ◽

S. Müller ◽

B. Weigmann ◽

M. Ramsperger-Gleixner ◽

N. Koch ◽

...

Keyword(s):

Mouse Model ◽

Human Platelets ◽

In Vivo Monitoring

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05 / Anti-inflammatory functionalized membrane for periodontal regeneration: in vivo evaluation in periodontitis-induced mouse model

10.26226/morressier.5ac3831b2afeeb00097a3ca4 ◽

2018 ◽

Author(s):

Fareeha Batool

Keyword(s):

Mouse Model ◽

Periodontal Regeneration ◽

In Vivo Evaluation ◽

Functionalized Membrane ◽

Anti Inflammatory

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Faculty Opinions recommendation of Interleukin-6 small interfering RNA improved the herpes simplex virus-induced systemic inflammation in vivo Behcet's disease-like mouse model.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1158441.618600 ◽

2009 ◽

Author(s):

Florence Apparailly ◽

Gabriel Courties

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Mouse Model ◽

Systemic Inflammation ◽

Interleukin 6 ◽

Small Interfering Rna ◽

Behcet’S Disease ◽

Simplex Virus ◽

Interfering Rna

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Faculty Opinions recommendation of In vivo genome editing restores haemostasis in a mouse model of haemophilia.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.12273956.14701094 ◽

2011 ◽

Author(s):

William H Colledge

Keyword(s):

Mouse Model ◽

Genome Editing

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Faculty Opinions recommendation of In vivo genome editing restores haemostasis in a mouse model of haemophilia.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.12273956.13449054 ◽

2011 ◽

Author(s):

Michel Sadelain ◽

Eirini Papapetrou

Keyword(s):

Mouse Model ◽

Genome Editing

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Faculty Opinions recommendation of Sirtuin 1 enzymatic activity is required for cartilage homeostasis in vivo in a mouse model.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717963530.793471854 ◽

2013 ◽

Author(s):

Johanne Martel-Pelletier ◽

Gladys Valverde-Franco

Keyword(s):

Mouse Model ◽

Enzymatic Activity ◽

Sirtuin 1 ◽

Cartilage Homeostasis

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Faculty Opinions recommendation of Cutting edge: retrobulbar inflammation, adipogenesis, and acute orbital congestion in a preclinical female mouse model of Graves' orbitopathy induced by thyrotropin receptor plasmid-in vivo electroporation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718052713.793485497 ◽

2013 ◽

Author(s):

Luigi Bartalena

Keyword(s):

Mouse Model ◽

Female Mouse ◽

Cutting Edge ◽

Thyrotropin Receptor ◽

In Vivo Electroporation ◽

Graves Orbitopathy

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