scholarly journals Osteopontin is produced by rat cardiac fibroblasts and mediates A(II)-induced DNA synthesis and collagen gel contraction.

1996 ◽  
Vol 98 (10) ◽  
pp. 2218-2227 ◽  
Author(s):  
N Ashizawa ◽  
K Graf ◽  
Y S Do ◽  
T Nunohiro ◽  
C M Giachelli ◽  
...  
Keyword(s):  
Dna Synthesis ◽  
Cardiac Fibroblasts ◽  
Collagen Gel ◽  
Collagen Gel Contraction

scholarly journals Angiotensin II Promotes Integrin-Mediated Collagen Gel Contraction by Adult Rat Cardiac Fibroblasts.

1999 ◽  
Vol 40 (4) ◽  
pp. 461-469 ◽  
Author(s):  
Tatsuya NUNOHIRO ◽  
Naoto ASHIZAWA ◽  
Kristof GRAF ◽  
Willa HSUEH ◽  
Katsusuke YANO
Keyword(s):  
Angiotensin Ii ◽  
Cardiac Fibroblasts ◽  
Collagen Gel ◽  
Adult Rat ◽  
Collagen Gel Contraction

Isotonic Biaxial Loading: An Economic, Versatile Method for the Study of Fibroblast-Populated Collagen Gels

1999 ◽  
Author(s):  
Jeffrey W. Holmes ◽  
Thomas K. Borg
Keyword(s):  
Biaxial Loading ◽  
Cardiac Fibroblasts ◽  
Collagen Gel ◽  
Simple System ◽  
Neonatal Rat ◽  
Collagen Gels ◽  
Maximal Contraction ◽  
Contraction Force ◽  
A Value ◽  
Collagen Gel Contraction

Abstract Studies of collagen gel contraction by embedded fibroblasts have characterized the response of free (unloaded) or isometric (maximally loaded) gels but not the response to intermediate loads. An inexpensive, simple system was devised to isotonically load fibroblast-populated collagen gels using freely hanging weights. This system provided excellent repeatability. Maximal contraction force was estimated at 1 mN per million cells in neonatal rat cardiac fibroblasts, a value that agreed well with reported isometric experiments in fibroblasts from other tissues. The ability to load uniaxially or biaxially and with variable loads will facilitate exploration of the regulation of fibroblast mechanics and biology by stress.

scholarly journals Stimulation of collagen gel contraction by angiotensin II and III in cardiac fibroblasts

2002 ◽  
Vol 3 (3) ◽  
pp. 160-166 ◽  
Author(s):  
Paul Lijnen ◽  
Victor Petrov ◽  
Kandelaria Rumilla ◽  
Robert Fagard
Keyword(s):  
Angiotensin Ii ◽  
Cardiac Fibroblasts ◽  
Collagen Gel ◽  
Collagen Gel Contraction ◽  
Stimulation Of
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