scholarly journals Evidence for a catabolic role of glucagon during an amino acid load.

1996 ◽  
Vol 98 (1) ◽  
pp. 90-99 ◽  
Author(s):  
M R Charlton ◽  
D B Adey ◽  
K S Nair
Keyword(s):  
Amino Acid ◽  
Amino Acid Load ◽  
Acid Load

THE CONTROL OF ARGININE-INDUCED INSULIN SECRETION IN THE RAT: THE ROLE OF CATECHOLAMINES

1973 ◽  
Vol 58 (1) ◽  
pp. 111-122 ◽  
Author(s):  
R. A. BACCHUS ◽  
L. MEADE ◽  
J. S. M. HUTCHINSON ◽  
D. R. LONDON
Keyword(s):  
Insulin Secretion ◽  
Blood Glucose ◽  
Amino Acid ◽  
Insulin Response ◽  
Catecholamine Metabolism ◽  
Catecholamine Synthesis ◽  
Amino Acid Load ◽  
Acid Load ◽  
Anaesthetized Rat

SUMMARY The effect of alterations in catecholamine metabolism on arginine-induced insulin release was studied in the anaesthetized rat. Alpha-methyl-p-tyrosine, which inhibits catecholamine synthesis, guanethidine, which prevents catecholamine release, and reserpine, which depletes catecholamine stores, all enhanced the secretion of insulin and reduced the rise in blood glucose after the amino acid load. Adrenalectomy, with or without corticosterone replacement, had a similar effect. Adrenaline inhibited the insulin response to arginine. It was concluded that in the rat, adrenergic mechanisms modulate the insulin response to arginine.

The disposal of an intravenously administered amino acid load across the human forearm

Metabolism ◽  
1982 ◽  
Vol 31 (5) ◽  
pp. 463-470 ◽  
Author(s):  
Naji N. Abumrad ◽  
David Rabin ◽  
Kendall L. Wise ◽  
W.W. Lacy
Keyword(s):  
Amino Acid ◽  
Amino Acid Load ◽  
Human Forearm ◽  
Acid Load

Biochemical and behavioural effects of acute tryptophan depletion in abstinent bulimic subjects: a pilot study

1995 ◽  
Vol 25 (5) ◽  
pp. 995-1001 ◽  
Author(s):  
A. Oldman ◽  
A. Walsh ◽  
P. Salkovskis ◽  
C. G. Fairburn ◽  
P. J. Cowen
Keyword(s):  
Amino Acid ◽  
Food Intake ◽  
Free Amino ◽  
Acute Tryptophan Depletion ◽  
Tryptophan Depletion ◽  
Healthy Controls ◽  
Behavioural Effects ◽  
Amino Acid Load ◽  
Healthy Female ◽  
Acid Load

SYNOPSISWe studied the effect of acute tryptophan (TRP) depletion in a group of eight abstinent bulimic (BN) subjects and in 12 healthy female controls. Despite being free of episodes of bingeeating and vomiting for a prolonged period, the abstinent BN subjects still appeared to practice dietary restraint as judged by their food intake in a test meal. In addition, their plasma TRP concentrations were significantly lower than those of the controls. Administration of a TRP-free amino acid load (52 g) significantly lowered plasma total and free TRP. However, compared to a balanced amino acid load, this procedure did not have significant effects on mood, appetite or food intake in either the abstinent BN subjects or the healthy controls.

scholarly journals Is hyperammonemia really the true cause of altered neuropsychology, brain MR spectroscopy and magnetization transfer after an oral amino acid load in cirrhosis?

Hepatology ◽  
2003 ◽  
Vol 38 (3) ◽  
pp. 777-777 ◽  
Author(s):  
Oliviero Riggio ◽  
Cesare Efrati ◽  
Andrea Masini ◽  
Stefania Angeloni ◽  
Manuela Merli
Keyword(s):  
Amino Acid ◽  
Mr Spectroscopy ◽  
Magnetization Transfer ◽  
Amino Acid Load ◽  
Acid Load

scholarly journals Taste aversion induced by an histidine-free amino acid load

1974 ◽  
Vol 2 (3) ◽  
pp. 349-351 ◽  
Author(s):  
D. A. Booth ◽  
P. C. Simson
Keyword(s):  
Amino Acid ◽  
Free Amino Acid ◽  
Taste Aversion ◽  
Free Amino ◽  
Amino Acid Load ◽  
Acid Load

Valine-Toxic Intermittent Maple Syrup Urine Disease: A Previously Unrecognized Variant

PEDIATRICS ◽  
1979 ◽  
Vol 63 (2) ◽  
pp. 286-294
Author(s):  
William B. Zipf ◽  
Virginia C. Hieber ◽  
Richard J. Allen
Keyword(s):  
Amino Acid ◽  
Maple Syrup Urine Disease ◽  
Cultured Cells ◽  
Variant Form ◽  
Maximum Serum ◽  
Maple Syrup ◽  
Amino Acid Load ◽  
Acid Load ◽  
Urine Disease ◽  
Load Tests

An 18-month-old boy with repeated episodes of vomiting, lethargy, irritability, acidosis, and hypoglycemia from the age of 2 months was proved to have a variant form of maple syrup urine disease (MSUD). Amino acid load tests for leucine, isoleucine, valine, and phenylalanine were performed and compared to similar tests in a child with classic MSUD; maximum serum concentrations during tolerance studies in our patient were 24, 16, 26, and 18 mg/dl, respectively. All amino acid challenges were tolerated well except for valine. Within one hour after valine administration the child developed symptoms of lethargy, vomiting, ataxia, irritability, and hypoglycemia. Cortisol, growth hormone, insulin, and glucagon response to hypoglycemia were normal. Filbroblasts studies on cultured cells from our patient demonstrated abnormally low rates of 14CO2 production from both 14C-labeled leucine and 14C-labeled valine. Decarboxylation with valine as substrate was significantly less than the decarboxylation with leucine. A proteinrestricted diet was started but he continued to have occasional symptomatic episodes of hyperaminoacidemia and at the age of 4 years died during one of these episodes. Results of neuropathologic studies differed from those reported in the literature for classic MSUD disease.

scholarly journals L-Amino acid load to enhance PET differentiation between tumor and inflammation: anin vitro study on18F-FET uptake

2006 ◽  
Vol 1 (5) ◽  
pp. 212-220 ◽  
Author(s):  
S. Laïque ◽  
D. Egrise ◽  
M. Monclus ◽  
F. Schmitz ◽  
C. Garcia ◽  
...  
Keyword(s):  
Amino Acid ◽  
Vitro Study ◽  
Amino Acid Load ◽  
Acid Load
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