scholarly journals Gender differences in regional fatty acid metabolism before and after meal ingestion.

1995 ◽  
Vol 96 (5) ◽  
pp. 2297-2303 ◽  
Author(s):  
M D Jensen
2011 ◽  
Vol 25 (S1) ◽  
Author(s):  
Katie M Lebold ◽  
Donald B Jump ◽  
Charlotte L Wright ◽  
Galen W Miller ◽  
Edwin M Labut ◽  
...  

2008 ◽  
Vol 22 (S1) ◽  
Author(s):  
Sylvia Santosa ◽  
Donald D Hensrud ◽  
Susanne B Votruba ◽  
Michael D Jensen

2008 ◽  
Vol 88 (4) ◽  
pp. 1134-1141 ◽  
Author(s):  
Sylvia Santosa ◽  
Donald D Hensrud ◽  
Susanne B Votruba ◽  
Michael D Jensen

1990 ◽  
Vol 29 (01) ◽  
pp. 28-34 ◽  
Author(s):  
F. C. Visser ◽  
M. J. van Eenige ◽  
G. Westera ◽  
J. P. Roos ◽  
C. M. B. Duwel

Changes in myocardial metabolism can be detected externally by registration of time-activity curves after administration of radioiodinated fatty acids. In this scintigraphic study the influence of lactate on fatty acid metabolism was investigated in the normal human myocardium, traced with 123l-17-iodoheptadecanoic acid (123l-17-HDA). In patients (paired, n = 7) lactate loading decreased the uptake of 123l-17-HDA significantly from 27 (control: 22-36) to 20 counts/min/pixel (16-31; p <0.05 Wilcoxon). The half-time value increased to more than 60 rriin (n = 5), oxidation decreased from 61 to 42%. Coronary vasodilatation, a well-known side effect of lactate loading, was studied separately in a dipyridamole study (paired, n = 6). Coronary vasodilatation did not influence the parameters of the time-activity curve. These results suggest that changes in plasma lactate level as occurring, among other effects, during exercise will influence the parameters of dynamic 123l-17-HDA scintigraphy of the heart.


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