scholarly journals HLA-DQ gene complementation and other histocompatibility relationships in man with the anti-Ro/SSA autoantibody response of systemic lupus erythematosus.

1990 ◽  
Vol 86 (2) ◽  
pp. 606-611 ◽  
Author(s):  
A Fujisaku ◽  
M B Frank ◽  
B Neas ◽  
M Reichlin ◽  
J B Harley
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Gene Complementation ◽  
Autoantibody Response ◽  
Hla Dq

scholarly journals Autoantibody response to adjuvant and nonadjuvant H1N1 vaccination in systemic lupus erythematosus

2011 ◽  
Vol 63 (11) ◽  
pp. 1517-1520 ◽  
Author(s):  
Murray B. Urowitz ◽  
Anoja Anton ◽  
Dominique Ibanez ◽  
Dafna D. Gladman
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Autoantibody Response

HLA-DQ, DR AND COMPLEMENT C4 VARIANTS IN SYSTEMIC LUPUS ERYTHEMATOSUS

Rheumatology ◽  
1993 ◽  
Vol 32 (10) ◽  
pp. 870-875 ◽  
Author(s):  
E. J. DAVIES ◽  
M. C. HILLARBY ◽  
R. G. COOPER ◽  
E. M. HAY ◽  
J. R. GREEN ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Complement C4 ◽  
Hla Dq

Development of the anti-Ro autoantibody response in a patient with systemic lupus erythematosus

1996 ◽  
Vol 39 (10) ◽  
pp. 1664-1668 ◽  
Author(s):  
R. Hal Scofield ◽  
Fenchung Zhang ◽  
Biji T. Kurien ◽  
Camille J. Anderson ◽  
Morris Reichlin ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Autoantibody Response

scholarly journals Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes.

1994 ◽  
Vol 179 (4) ◽  
pp. 1317-1330 ◽  
Author(s):  
L A Casciola-Rosen ◽  
G Anhalt ◽  
A Rosen
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Subcellular Location ◽  
Oxidative Modification ◽  
Apoptotic Cells ◽  
Systemic Lupus ◽  
Nucleosomal Dna ◽  
Autoantibody Response ◽  
Two Populations ◽  
Small Nuclear Ribonucleoproteins

Systemic lupus erythematosus is a multisystem autoimmune disease in which the autoantibody response targets a variety of autoantigens of diverse subcellular location. We show here that these autoantigens are clustered in two distinct populations of blebs at the surface of apoptotic cells. The population of smaller blebs contains fragmented endoplasmic reticulum (ER) and ribosomes, as well as the ribonucleoprotein, Ro. The larger blebs (apoptotic bodies) contain nucleosomal DNA, Ro, La, and the small nuclear ribonucleoproteins. These autoantigen clusters have in common their proximity to the ER and nuclear membranes, sites of increased generation of reactive oxygen species in apoptotic cells. Oxidative modification at these sites may be a mechanism that unites this diverse group of molecules together as autoantigens.

Cooperative Association of T Cell β Receptor and HLA-DQ Alleles in the Production of Anti-Ro in Systemic Lupus Erythematosus

1994 ◽  
Vol 72 (3) ◽  
pp. 335-341 ◽  
Author(s):  
R.Hal Scofield ◽  
Mark Barton Frank ◽  
Barbara R. Neas ◽  
Robert M. Horowitz ◽  
Kathy L. Hardgrave ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
T Cell ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Hla Dq ◽  
Β Receptor ◽  
Cooperative Association

Differential contribution of C4 and HLA-DQ genes to systemic lupus erythematosus susceptibility

1993 ◽  
Vol 91 (6) ◽  
pp. 579-584 ◽  
Author(s):  
Dolores De Juan ◽  
José M. Martín-Villa ◽  
Juan J. Gómez-Reino ◽  
José L. Vicario ◽  
Alfredo Corell ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Systemic Lupus Erythematosus Susceptibility ◽  
Hla Dq ◽  
Differential Contribution
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