scholarly journals Isolation of a complementary DNA clone for thyroid microsomal antigen. Homology with the gene for thyroid peroxidase.

1987 ◽  
Vol 80 (4) ◽  
pp. 1205-1208 ◽  
Author(s):  
P Seto ◽  
H Hirayu ◽  
R P Magnusson ◽  
J Gestautas ◽  
L Portmann ◽  
...  
Keyword(s):  
Thyroid Peroxidase ◽  
Complementary Dna ◽  
Thyroid Microsomal Antigen ◽  
Microsomal Antigen

scholarly journals Characterization of the thyroid microsomal antigen, and its relationship to thyroid peroxidase, using monoclonal antibodies.

1988 ◽  
Vol 81 (4) ◽  
pp. 1217-1224 ◽  
Author(s):  
L Portmann ◽  
F W Fitch ◽  
W Havran ◽  
N Hamada ◽  
W A Franklin ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Thyroid Peroxidase ◽  
Thyroid Microsomal Antigen ◽  
Microsomal Antigen

Structure-activity analysis of microsomal antigen/thyroid peroxidase

1987 ◽  
Vol 53 (1-2) ◽  
pp. 15-23 ◽  
Author(s):  
Y. Nakajima ◽  
R.D. Howells ◽  
C. Pegg ◽  
E.Davies Jones ◽  
B.Rees Smith
Keyword(s):  
Activity Analysis ◽  
Thyroid Peroxidase ◽  
Structure Activity ◽  
Microsomal Antigen

Cellular localization of the microsomal antigen and the thyroid peroxidase antigen

1987 ◽  
Vol 116 (1_Suppl) ◽  
pp. S57-S62 ◽  
Author(s):  
A. Pinchera ◽  
S. Mariotti ◽  
L. Chiovato ◽  
P. Vitti ◽  
G. Lopez ◽  
...  
Keyword(s):  
Cellular Localization ◽  
Biochemical Characterization ◽  
Human Thyroid ◽  
Thyroid Peroxidase ◽  
Immunofluorescence Analysis ◽  
Thyroid Cells ◽  
Hla Dr ◽  
Microsomal Antigen ◽  
Dependent Mechanism

Abstract. Evidence has been accumulated that human thyroid microsomal/microvillar autoantigen (M) is expressed both in the cytoplasm and on the surface of thyroid follicular cells. The availability of this autoantigen to the immune system, possibly associated with abnormally expressed HLA-DR antigens may be relevant both to the triggering and to maintenance of thyroid autoimmune reactions. Preliminary biochemical characterization of M suggested that it was a glycoprotein with a mol. wt. of about 100–110 kD. recent studies carried out in our laboratories taking advantage of monoclonal antibodies provided evidence that the structure presently referred as M-Ag is represented by thyroid peroxidase (TPO). The identity between TPO and M is further supported by four-layer immunofluorescence analysis showing a complete overlap of the two antigens both in the surface and in the cytoplasm of thyroid cells and by the observation that the expression of M and TPO is similarly modulated by TSH, possibly through a cAMP-dependent mechanism.

Thyroid Peroxidase and the “Microsomal Antigen” Cannot be Distinguished by Immunofluorescence on Cultured Thyroid Cells

1987 ◽  
pp. 293-295
Author(s):  
L. Chiovato ◽  
P. Vitti ◽  
C. Mammoli ◽  
G. Lopez ◽  
P. Cucchi ◽  
...  
Keyword(s):  
Thyroid Peroxidase ◽  
Thyroid Cells ◽  
Microsomal Antigen

Solubilization of Human Thyroid Microsomal Antigen*

1979 ◽  
Vol 48 (2) ◽  
pp. 207-212 ◽  
Author(s):  
S. MARIOTTI ◽  
A. PINCHERA ◽  
C. MARCOCCI ◽  
P. VITTI ◽  
C. URBANO ◽  
...  
Keyword(s):  
Human Thyroid ◽  
Thyroid Microsomal Antigen ◽  
Microsomal Antigen

IMMUNOELECTRON MICROSCOPIC STUDY OF THYROID MICROSOMAL ANTIGEN

1988 ◽  
Vol 38 (9) ◽  
pp. 1141-1148
Author(s):  
Shigeo Yokoyama ◽  
Iwao Nakayama ◽  
Shiro Noguchi
Keyword(s):  
Microscopic Study ◽  
Thyroid Microsomal Antigen ◽  
Microsomal Antigen

scholarly journals Labelling and immunoprecipitation of thyroid microsomal antigen

FEBS Letters ◽  
1985 ◽  
Vol 187 (2) ◽  
pp. 334-338 ◽  
Author(s):  
Y. Kajita ◽  
D. Morgan ◽  
A.B. Parkes ◽  
B. Rees Smith
Keyword(s):  
Thyroid Microsomal Antigen ◽  
Microsomal Antigen
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