scholarly journals Human monoclonal antibodies that recognize conserved epitopes in the core-lipid A region of lipopolysaccharides.

1987 ◽  
Vol 79 (5) ◽  
pp. 1421-1430 ◽  
Author(s):  
M Pollack ◽  
A A Raubitschek ◽  
J W Larrick
Keyword(s):  
Monoclonal Antibodies ◽  
Lipid A ◽  
Human Monoclonal Antibodies ◽  
The Core ◽  
Core Lipid

THE STRUCTURES OF THE CORE-LIPID A REGIONS OF LIPOPOLYSACCHARIDES FROM SERRATIA MARCESCENS

2002 ◽  
Author(s):  
Evgeny Vinogradov ◽  
Buko Lindner ◽  
Guntram Seltmann ◽  
Joanna Radziejewska-Lebrecht ◽  
Otto Holst
Keyword(s):  
Serratia Marcescens ◽  
Lipid A ◽  
The Core ◽  
Core Lipid

The structure of the carbohydrate backbone of the core–lipid A region of the lipopolysaccharide from Proteus vulgaris serotype O25

2000 ◽  
Vol 328 (4) ◽  
pp. 533-538 ◽  
Author(s):  
Evgeny Vinogradov ◽  
Maciej Cedzynski ◽  
Antoni Rozalski ◽  
Andrzej Ziolkowski ◽  
Anna Swierzko
Keyword(s):  
Lipid A ◽  
Proteus Vulgaris ◽  
The Core ◽  
Core Lipid

Identification of two core types in lipopolysaccharides ofActinobacillus pleuropneumoniaerepresenting serotypes 1 to 12

1996 ◽  
Vol 42 (8) ◽  
pp. 855-858 ◽  
Author(s):  
Mario Jacques ◽  
Stéphane Rioux ◽  
Sonia-Élaine Paradis ◽  
Caroline Bégin ◽  
Marcelo Gottschalk
Keyword(s):  
Western Blot ◽  
Salmonella Typhimurium ◽  
Gel Electrophoresis ◽  
Lipid A ◽  
Polyacrylamide Gel Electrophoresis ◽  
Actinobacillus Pleuropneumoniae ◽  
Type I ◽  
Type Ii ◽  
The Core ◽  
Core Lipid

Lipopolysaccharides (LPS) of Actinobacillus pleuropneumoniae were separated by Tricine–SDS–polyacrylamide gel electrophoresis, which has been shown to improve resolution of low-molecular-mass fast migrating bands. Strains representing the 12 serotypes of A. pleuropneumoniae can be divided in two groups according to the gel mobility of the core–lipid A region of their LPS. The first electromorphic core type (core type I), found in serotypes 1, 6, 9, and 11, had a migration slower than Salmonella typhimurium Ra LPS. The second electromorphic core type (core type II), found in the remaining serotypes (i.e., 2, 3, 4, 5, 7, 8, 10, and 12) had a migration similar to S. typhimurium Ra LPS. Furthermore, we observed that these two core types were antigenically different. Western blot analyses indicated that core – lipid A region of LPS from electromorphic core type I strains reacted when probed with serum from a pig experimentally infected with a core type I strain but not when probed with serum from a pig experimentally infected with a core type II strain. Conversely, core – lipid A region of LPS from electromorphic core type II strains reacted only when probed with serum from a pig experimentally infected with a core type II strain. Our results, based on both electrophoretic mobility and antigenicity, suggest the presence of two LPS core types in A. pleuropneumoniae.Key words: Actinobacillus pleuropneumoniae, lipopolysaccharides, core.

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