scholarly journals Influence of Cl- on organic anion transport in short-term cultured rat hepatocytes and isolated perfused rat liver.

1987 ◽  
Vol 79 (4) ◽  
pp. 1259-1268 ◽  
Author(s):  
A W Wolkoff ◽  
A C Samuelson ◽  
K L Johansen ◽  
R Nakata ◽  
D M Withers ◽  
...  
Keyword(s):  
Rat Liver ◽  
Organic Anion ◽  
Rat Hepatocytes ◽  
Anion Transport ◽  
Isolated Perfused Rat Liver ◽  
Perfused Rat Liver ◽  
Organic Anion Transport ◽  
Short Term ◽  
Cultured Rat Hepatocytes

Inhibition by extracellular ATP of organic anion transport in the perfused rat liver

2002 ◽  
Vol 454 (2-3) ◽  
pp. 225-234 ◽  
Author(s):  
Talma R.L Fernandes ◽  
Denise S de Oliveira ◽  
Fumie Suzuki-Kemmelmeier ◽  
Adelar Bracht
Keyword(s):  
Rat Liver ◽  
Organic Anion ◽  
Anion Transport ◽  
Extracellular Atp ◽  
Perfused Rat Liver ◽  
Organic Anion Transport

Redistribution of canalicular organic anion transport activity in isolated and cultured rat hepatocytes

Hepatology ◽  
1995 ◽  
Vol 21 (6) ◽  
pp. 1649-1657 ◽  
Author(s):  
Han Roelofsen ◽  
Conny T. M. Bakker ◽  
Berry Schoemaker ◽  
Marc Heijn ◽  
Peter L. M. Jansen ◽  
...  
Keyword(s):  
Organic Anion ◽  
Rat Hepatocytes ◽  
Anion Transport ◽  
Organic Anion Transport ◽  
Transport Activity ◽  
Cultured Rat Hepatocytes ◽  
Anion Transport Activity

A Comparison of Plasminogen Activators Derived from Rat Plasma, Primary Rat Hepatocytes and Isolated Perfused Rat Liver

1982 ◽  
Vol 47 (02) ◽  
pp. 166-172 ◽  
Author(s):  
Yoav Sharoni ◽  
Maria C Topal ◽  
Patricia R Tuttle ◽  
Henry Berger
Keyword(s):  
Rat Liver ◽  
Isoelectric Point ◽  
Rat Hepatocytes ◽  
Cell Types ◽  
Plasminogen Activators ◽  
Rat Plasma ◽  
Isolated Perfused Rat Liver ◽  
Perfused Rat Liver ◽  
Molecular Weights ◽  
Physiological Relevance

SummaryOf the two cell types it was possible to culture from the dissociated rat liver, hepatocytes and Kupffer cells, only the former were fibrinolytically active. Rat hepatocytes during the first 24 hr in culture secreted two plasminogen activators with molecular weights identical to those found in rat plasma, an 80,000-dalton form (PA-80) and a 45,000-dalton form (PA-45). Partially purified preparations of plasminogen activators from both sources were subjected to isoelectric focusing (IEF) to compare characteristics further. There were three distinct peaks of PA-45 in each preparation with isoelectric points of 7.1, 7.2 and 7.4; all electrophoretic forms had the same low affinity to fibrin. PA-80 from both sources displayed similar IEF profiles with forms ranging from pH values of 7 to 8, all with the same high affinity to fibrin. The major form of PA-80 in the plasma preparation had an isoelectric point of 7.9 whereas that in the hepatocyte preparation had an isoelectric point of 7.6. The isolated perfused rat liver was also shown to produce both PA-80 and PA-45 emphasizing the physiological relevance of the findings with hepatocytes. It is concluded that in the rat hepatocytes contribute to the plasma profile with regard to the plasminogen activator content.

scholarly journals Stable Inducible Expression of a Functional Rat Liver Organic Anion Transport Protein in HeLa Cells

1995 ◽  
Vol 270 (43) ◽  
pp. 25591-25595 ◽  
Author(s):  
Xiaoying Shi ◽  
Shuang Bai ◽  
Allison C. Ford ◽  
Robert D. Burk ◽  
Emmanuel Jacquemin ◽  
...  
Keyword(s):  
Rat Liver ◽  
Hela Cells ◽  
Organic Anion ◽  
Anion Transport ◽  
Inducible Expression ◽  
Transport Protein ◽  
Organic Anion Transport

Kupffer cells alter organic anion transport through multidrug resistance protein 2 in the post-cold ischemic rat liver

Hepatology ◽  
2004 ◽  
Vol 39 (4) ◽  
pp. 1099-1109 ◽  
Author(s):  
Atsushi Kudo ◽  
Satoshi Kashiwagi ◽  
Mayumi Kajimura ◽  
Yasunori Yoshimura ◽  
Koji Uchida ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Rat Liver ◽  
Kupffer Cells ◽  
Organic Anion ◽  
Anion Transport ◽  
Multidrug Resistance Protein ◽  
Organic Anion Transport ◽  
Multidrug Resistance Protein 2 ◽  
Resistance Protein
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