scholarly journals The effect of Tuftsin on the nitrous blue tetrazolium reduction of normal human polymorphonuclear leukocytes.

1975 ◽  
Vol 55 (1) ◽  
pp. 198-200 ◽  
Author(s):  
Z Spirer ◽  
V Zakuth ◽  
A Golander ◽  
N Bogair ◽  
M Fridkin
Blood ◽  
1976 ◽  
Vol 48 (2) ◽  
pp. 309-313 ◽  
Author(s):  
RL Baehner ◽  
LA Boxer ◽  
J Davis

Normal human polymorphonuclear leukocytes (PMN) placed in anaerobic chambers reaching pO2's of less than 5 mm Hg fail to generate O2-, iodinate ingested particles, and stimulate glucose-1–14C oxidation through the hexose monophosphate shunt. The observation that anaerobic cells are incapable of generating O2- or reducing nitroblue tetrazolium (NBT) to formazan supports the idea that NBT reduction in phagocytizing PMN is due exclusively to oxygen-dependent O2- generating oxidase which is deficient in chronic granulomatous disease leukocytes, despite their hyperphagocytic capacity.


Blood ◽  
1976 ◽  
Vol 48 (2) ◽  
pp. 309-313 ◽  
Author(s):  
RL Baehner ◽  
LA Boxer ◽  
J Davis

Abstract Normal human polymorphonuclear leukocytes (PMN) placed in anaerobic chambers reaching pO2's of less than 5 mm Hg fail to generate O2-, iodinate ingested particles, and stimulate glucose-1–14C oxidation through the hexose monophosphate shunt. The observation that anaerobic cells are incapable of generating O2- or reducing nitroblue tetrazolium (NBT) to formazan supports the idea that NBT reduction in phagocytizing PMN is due exclusively to oxygen-dependent O2- generating oxidase which is deficient in chronic granulomatous disease leukocytes, despite their hyperphagocytic capacity.


Cytometry ◽  
1990 ◽  
Vol 11 (8) ◽  
pp. 907-912 ◽  
Author(s):  
Andrea Fattorossi ◽  
Roberto Nisini ◽  
Soccorsa Le Moli ◽  
Guido De Petrillo ◽  
Raffaele D'Amelio

1984 ◽  
Vol 43 (2) ◽  
pp. 744-752 ◽  
Author(s):  
P Robinson ◽  
D Wakefield ◽  
S N Breit ◽  
J F Easter ◽  
R Penny

1975 ◽  
Vol 131 (Supplement) ◽  
pp. S73-S80 ◽  
Author(s):  
K. R. Ratzan ◽  
C. Giraudo ◽  
C. Amado ◽  
I. Lauredo ◽  
G. Horowitz

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